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ONTOLOGY REPORT - ANNOTATIONS

Term:methionyl-tRNA formyltransferase activity
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Accession:GO:0004479 term browser browse the term
Definition:Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.
Synonyms:related_synonym: 10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity;   N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity;   N-terminal peptidyl-methionine N-formylation;   N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity;   conversion of met-tRNAf to fmet-tRNA;   conversion of mitochondrial met-tRNAf to fmet-tRNA;   formylmethionyl-transfer ribonucleic synthetase activity;   methionyl ribonucleic formyltransferase activity;   methionyl-tRNA Met formyltransferase activity;   methionyl-tRNA transformylase activity;   methionyl-transfer RNA transformylase activity;   methionyl-transfer ribonucleate methyltransferase activity;   methionyl-transfer ribonucleic transformylase activity;   mitochondrial N-terminal peptidyl-methionine N-formylation
 alt_id: GO:0001718;   GO:0070128
 xref: EC:2.1.2.9;   MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN;   RHEA:24380;   reactome:R-HSA-5389841 "MTFMT formylates methionyl-tRNA"


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methionyl-tRNA formyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:123,166,630...123,244,257
Ensembl chr 3:130,484,862...130,562,934 		JBrowse link
G MTFMT mitochondrial methionyl-tRNA formyltransferase enables IEA UniProt
Ensembl
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr15:43,942,227...43,969,182
Ensembl chr15:62,225,620...62,253,612 		JBrowse link
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  molecular_function 19298
    catalytic activity 6350
      catalytic activity, acting on a nucleic acid 627
        catalytic activity, acting on RNA 388
          catalytic activity, acting on a tRNA 134
            methionyl-tRNA formyltransferase activity 2
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