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ONTOLOGY REPORT - ANNOTATIONS

Term:isocitrate dehydrogenase (NAD+) activity
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Accession:GO:0004449 term browser browse the term
Definition:Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.
Synonyms:related_synonym: NAD dependent isocitrate dehydrogenase activity;   NAD isocitric dehydrogenase activity;   NAD-linked isocitrate dehydrogenase activity;   NAD-specific isocitrate dehydrogenase activity;   isocitrate:NAD+ oxidoreductase (decarboxylating);   nicotinamide adenine dinucleotide isocitrate dehydrogenase activity
 xref: EC:1.1.1.41;   RHEA:23632;   Reactome:R-HSA-70967 "IDH3 complex decarboxylates isocitrate"


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isocitrate dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha enables IDA
ISO
IBA
IEA 		(PMID:2252888), (PMID:6853513)
(PMID:14555658), (PMID:16737955), (PMID:17432878), (PMID:28098230), (PMID:33349631), (PMID:4336621)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000003
GO_REF:0000116 		RGD
GO_Central
Ensembl
UniProt
RHEA		 PMID:2252888 PMID:4336621 PMID:6853513 PMID:14555658 PMID:16737955 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116, RGD:70770 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma enables ISS
ISO 		GO_REF:0000024
(PMID:2605193) 		UniProt
RGD		 PMID:2605193 GO_REF:0000024 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21102
    catalytic activity 6213
      oxidoreductase activity 865
        oxidoreductase activity, acting on CH-OH group of donors 163
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 154
            isocitrate dehydrogenase [NAD(P)+] activity 4
              isocitrate dehydrogenase (NAD+) activity 2
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