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ONTOLOGY REPORT - ANNOTATIONS

Term:isocitrate dehydrogenase [NAD(P)+] activity
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Accession:GO:0004448 term browser browse the term
Definition:Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.
Synonyms:exact_synonym: isocitrate dehydrogenase activity;   oxalosuccinic decarboxylase activity
 related_synonym: IDH activity;   IDP activity;   isocitric acid dehydrogenase activity;   isocitric dehydrogenase activity;   oxalosuccinate carboxylase activity;   oxalosuccinate decarboxylase activity


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isocitrate dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:14555658), (PMID:16737955), (PMID:17432878), (PMID:28098230), (PMID:33349631), (PMID:4336621)
(PMID:2252888), (PMID:6853513)		 GO_Central
RGD		 PMID:2252888 PMID:4336621 PMID:6853513 PMID:14555658 PMID:16737955 More... GO_REF:0000033, RGD:70770 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma enables ISS
ISO		 GO_REF:0000024
(PMID:2605193)		 UniProt
RGD		 PMID:2605193 GO_REF:0000024 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171 		JBrowse link
isocitrate dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 enables TAS
IDA
ISO
ISS
IEA
IBA		 (PMID:10521434), (PMID:19935646), (PMID:20171178)
GO_REF:0000024
GO_REF:0000117
GO_REF:0000033
(PMID:1180875), (PMID:12031902), (PMID:18275837), (PMID:1914521)		 RGD
UniProt
GO_Central		 PMID:1180875 PMID:1914521 PMID:10521434 PMID:12031902 PMID:18275837 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000117, RGD:633072, RGD:1624966 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 enables IDA
IEA
ISS
ISO
IBA		 GO_REF:0000116
GO_REF:0000003
GO_REF:0000024
GO_REF:0000117
GO_REF:0000002
(PMID:22416140), (PMID:23226729)
GO_REF:0000033
(PMID:18275837), (PMID:7323947), (PMID:8867815)		 RHEA
UniProt
InterPro
RGD
GO_Central		 PMID:7323947 PMID:8867815 PMID:18275837 PMID:22416140 PMID:23226729 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 GO_REF:0000117, RGD:11522739 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            isocitrate dehydrogenase [NAD(P)+] activity 4
              isocitrate dehydrogenase (NAD+) activity 2
              isocitrate dehydrogenase (NADP+) activity 2
paths to the root