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ONTOLOGY REPORT - ANNOTATIONS

Term:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
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Accession:GO:0004316 term browser browse the term
Definition:Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.
Synonyms:exact_synonym: 3-oxoacyl-ACP reductase activity
 related_synonym: (3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity;   3-ketoacyl acyl carrier protein reductase activity;   3-oxoacyl-ACPreductase activity;   3-oxoacyl-acyl-carrier-protein reductase activity;   NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity;   beta-ketoacyl reductase activity;   beta-ketoacyl thioester reductase activity;   beta-ketoacyl-ACP reductase activity;   beta-ketoacyl-acyl carrier protein reductase activity;   beta-ketoacyl-acyl-carrier protein(ACP) reductase activity
 xref: EC:1.1.1.100;   MetaCyc:3-OXOACYL-ACP-REDUCT-RXN;   RHEA:17397;   reactome:R-HSA-8862152 "2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP"


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3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr4 carbonyl reductase 4 enables ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:Q92506 (PMID:19571038), (PMID:25203508)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19571038 PMID:25203508 GO_REF:0000024 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Fasn fatty acid synthase enables IEA GO_REF:0000116
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 2
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