Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:carbonyl reductase (NADPH) activity
go back to main search page
Accession:GO:0004090 term browser browse the term
Definition:Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.
Synonyms:narrow_synonym: prostaglandin 9-ketoreductase activity;   xenobiotic ketone reductase activity
 related_synonym: ALR3;   NADPH-dependent carbonyl reductase activity;   NADPH2-dependent carbonyl reductase activity;   aldehyde reductase 1;   aldehyde reductase I activity;   carbonyl reductase activity;   nonspecific NADPH-dependent carbonyl reductase activity;   secondary-alcohol:NADP+ oxidoreductase activity
 xref: EC:1.1.1.184;   MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN;   RHEA:19257;   reactome:R-HSA-8937419 "CBR3 reduces DOX to DOXOL"


show annotations for term's descendants           Sort by:
carbonyl reductase (NADPH) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 enables IDA
ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:18449627), (PMID:1921984)
GO_REF:0000033
GO_REF:0000104		 UniProt
RGD
GO_Central		 PMID:1921984 PMID:18449627 PMID:12396270 PMID:7705364 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104, RGD:634703, RGD:69801 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cbr1l1 carbonyl reductase 1 like 1 enables IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr11:32,876,563...32,884,234
Ensembl chr11:32,857,991...32,895,275 		JBrowse link
G Cbr1l2 carbonyl reductase 1 like 2 enables IBA
IEA		 GO_REF:0000033
GO_REF:0000104		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275 		JBrowse link
G Cbr1l3 carbonyl reductase 1 like 3 enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr11:32,985,136...32,992,000
Ensembl chr11:32,985,707...32,992,000 		JBrowse link
G Cbr2 carbonyl reductase 2 enables IBA
ISO		 GO_REF:0000033
(PMID:7705352)		 GO_Central
RGD		 PMID:7705352 GO_REF:0000033 NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001 		JBrowse link
G Cbr2l1 carbonyl reductase 2 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,033,250...106,036,852
Ensembl chr10:106,033,255...106,036,919 		JBrowse link
G Cbr3 carbonyl reductase 3 enables IDA
ISO
IBA		 (PMID:18493841)
GO_REF:0000033		 RGD
GO_Central		 PMID:18493841 PMID:18983987 GO_REF:0000033, RGD:2316293 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs1 dehydrogenase/reductase 1 enables ISO (PMID:30031147) RGD PMID:30031147 NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 enables ISO
IBA		 (PMID:16685466)
GO_REF:0000033		 RGD
GO_Central		 PMID:16685466 GO_REF:0000033 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs2l1 dehydrogenase/reductase member 2 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:28,635,197...28,638,087
Ensembl chr15:28,635,197...28,638,087 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 enables ISO
IBA		 (PMID:18571493), (PMID:19056333)
(PMID:23128527)
GO_REF:0000033		 RGD
GO_Central		 PMID:18571493 PMID:19056333 PMID:23128527 GO_REF:0000033 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 enables ISO (PMID:24246760), (PMID:26466768), (PMID:28457967), (PMID:28687384) RGD PMID:24246760 PMID:26466768 PMID:28457967 PMID:28687384 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20626
    catalytic activity 6028
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            alcohol dehydrogenase [NAD(P)+] activity 63
              aldo-keto reductase (NADPH) activity 45
                alcohol dehydrogenase (NADP+) activity 41
                  carbonyl reductase (NADPH) activity 14
paths to the root