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ONTOLOGY REPORT - ANNOTATIONS

Term:aminomethyltransferase activity
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Accession:GO:0004047 term browser browse the term
Definition:Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
Synonyms:related_synonym: S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity;   T-protein;   glycine synthase activity;   glycine-cleavage system T-protein activity;   protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity;   protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity;   tetrahydrofolate aminomethyltransferase activity
 xref: EC:2.1.2.10;   MetaCyc:GCVT-RXN;   RHEA:16945;   reactome:R-HSA-5693977 "AMT transfers NH2CH2 from GCSH:SAMDLL to THF"


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aminomethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMT aminomethyltransferase enables IEA UniProt
Ensembl
InterPro
RHEA		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 3:49,344,590...49,350,383
Ensembl chr 3:50,589,193...50,594,968 		JBrowse link
G GCSH glycine cleavage system protein H ISO RGD PMID:6402507 RGD:1598699 NCBI chr16:61,688,959...61,702,364 JBrowse link
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  molecular_function 19294
    catalytic activity 5411
      transferase activity 2148
        transferase activity, transferring one-carbon groups 204
          hydroxymethyl-, formyl- and related transferase activity 9
            aminomethyltransferase activity 2
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