ONTOLOGY REPORT - ANNOTATIONS
Term: aldose reductase (NADPH) activity
Accession: GO:0004032
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Definition: Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
Synonyms: exact_synonym: alditol:NADP+ 1-oxidoreductase activity
related_synonym: aldehyde reductase activity; aldose reductase activity; polyol dehydrogenase (NADP(+)) activity
xref: KEGG_REACTION:R02820; RHEA:12789; reactome:R-HSA-196060 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol"; reactome:R-HSA-5652172 "AKR1B1 reduces Glc to D-sorbitol"
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ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr32:21,282,526...21,299,387
Ensembl chr32:21,282,890...21,299,328
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AKR1A1
aldo-keto reductase family 1 member A1
enables
ISO
(PMID:14667815), (PMID:15769935)
MGI
PMID:14667815 PMID:15769935
NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592
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AKR1B1
aldo-keto reductase family 1 member B
enables
ISO
(PMID:7851421) (PMID:1420136), (PMID:2112546), (PMID:8645003) (PMID:17727625) (PMID:8435445)
MGI Reactome RGD UniProt
PMID:1420136 PMID:2112546 PMID:2114645 PMID:7851421 PMID:8435445 PMID:8645003 PMID:17727625 More...
RGD:1626085
NCBI chr14:2,991,888...3,006,941
Ensembl chr14:2,991,888...3,006,940
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AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
enables
ISO
(PMID:21232532)
RGD UniProt
PMID:8977402 PMID:21232532
RGD:10053609
NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043
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AKR7A2
aldo-keto reductase family 7 member A2
ISO
RGD
PMID:12071861
RGD:625492
NCBI chr 2:79,334,179...79,343,880
Ensembl chr 2:79,334,205...79,343,007
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