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ONTOLOGY REPORT - ANNOTATIONS

Term:L-iditol 2-dehydrogenase (NAD+) activity
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Accession:GO:0003939 term browser browse the term
Definition:Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.
Synonyms:broad_synonym: polyol dehydrogenase activity
 related_synonym: L-iditol (sorbitol) dehydrogenase activity;   L-iditol:NAD oxidoreductase activity;   L-iditol:NAD+ 5-oxidoreductase activity;   NAD-dependent sorbitol dehydrogenase activity;   NAD-sorbitol dehydrogenase;   glucitol dehydrogenase activity;   sorbitol dehydrogenase activity
 xref: EC:1.1.1.14;   MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN;   reactome:R-HSA-5652195 "SORD oxidizes D-sorbitol to Fru"


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L-iditol 2-dehydrogenase (NAD+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sord sorbitol dehydrogenase enables ISO
IEA
IBA		 (PMID:32367058), (PMID:3365415), (PMID:6870831), (PMID:8487505)
GO_REF:0000104
GO_REF:0000107
MGI:3616090 (PMID:1914521), (PMID:6626150), (PMID:7171128), (PMID:722274), (PMID:9403062), (PMID:9604875)
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:722274 PMID:1914521 PMID:3365415 PMID:6626150 PMID:6870831 More... GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
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Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      oxidoreductase activity 868
        oxidoreductase activity, acting on CH-OH group of donors 165
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 156
            alcohol dehydrogenase [NAD(P)+] activity 67
              alcohol dehydrogenase (NAD+) activity 25
                L-iditol 2-dehydrogenase (NAD+) activity 1
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