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ONTOLOGY REPORT - ANNOTATIONS

Term:IMP dehydrogenase activity
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Accession:GO:0003938 term browser browse the term
Definition:Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
Synonyms:related_synonym: IMP oxidoreductase activity;   IMP:NAD+ oxidoreductase activity;   inosinate dehydrogenase activity;   inosine 5'-monophosphate dehydrogenase activity;   inosine monophosphate dehydrogenase activity;   inosine monophosphate oxidoreductase activity;   inosine-5'-phosphate dehydrogenase activity;   inosinic acid dehydrogenase activity
 xref: EC:1.1.1.205;   MetaCyc:IMP-DEHYDROG-RXN;   RHEA:11708;   Reactome:R-HSA-9748945 "IMPDH tetramers dehydrogenate 6TIMP to 6TXMP";   reactome:R-HSA-73794 "IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2]"


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IMP dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Impdh1 inosine monophosphate dehydrogenase 1 enables IEA
IBA
ISO		 GO_REF:0000003
GO_REF:0000104
GO_REF:0000033
(PMID:12944494), (PMID:31838626)		 UniProt
GO_Central
RGD		 PMID:12944494 PMID:31838626 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:57,801,842...57,817,434
Ensembl chr 4:57,801,831...57,819,076 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 enables IDA
ISO
IEA
IBA		 (PMID:7903306)
GO_REF:0000104
GO_REF:0000033
(PMID:12944494), (PMID:1671845)		 RGD
UniProt
GO_Central		 PMID:1671845 PMID:7903306 PMID:12944494 PMID:2897864 GO_REF:0000033 GO_REF:0000104, RGD:5147398 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            IMP dehydrogenase activity 2
paths to the root