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ONTOLOGY REPORT - ANNOTATIONS

Term:methylated-DNA-[protein]-cysteine S-methyltransferase activity
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Accession:GO:0003908 term browser browse the term
Definition:Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
Synonyms:exact_synonym: MGMT
 broad_synonym: O6-alkylguanine-DNA alkyltransferase
 related_synonym: 6-O-methylguanine-DNA methyltransferase activity;   DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity;   O-6-methylguanine-DNA-alkyltransferase activity
 xref: EC:2.1.1.63;   MetaCyc:2.1.1.63-RXN;   RHEA:24000;   reactome:R-HSA-73892 "MGMT/hAGT mediated DNA Damage Reversal"


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methylated-DNA-[protein]-cysteine S-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:15025514 GO_REF:0000002 GO_REF:0000033, RGD:2316914 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 105
          methylated-DNA-[protein]-cysteine S-methyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21091
    catalytic activity 6174
      transferase activity 2443
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            S-methyltransferase activity 10
              methylated-DNA-[protein]-cysteine S-methyltransferase activity 1
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