3-hydroxybutyrate dehydrogenase activity - Ontology Report

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Term:	3-hydroxybutyrate dehydrogenase activity	go back to main search page
Accession:	GO:0003858	browse the term
Definition:	Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + H+ + NADH.
Synonyms:	related_synonym:	D-beta-hydroxybutyrate dehydrogenase activity
	xref:	EC:1.1.1.30; KEGG_REACTION:R01361; MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN; RHEA:20521; reactome:R-HSA-5696457 "BDH2 dehydrogenates 3HBA"; reactome:R-HSA-73912 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+"; reactome:R-HSA-73920 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+"

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Genes (2)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bdh1

3-hydroxybutyrate dehydrogenase 1

enables

(PMID:8679568)
GO_REF:0000033

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

3-hydroxybutyrate dehydrogenase 2

enables

(PMID:16380372)
GO_REF:0000107
GO_REF:0000033

GO_REF:0000033 GO_REF:0000107

NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072

Term paths to the root

Path 1
Term	Annotations
molecular_function	20633
catalytic activity	6032
oxidoreductase activity	854
oxidoreductase activity, acting on CH-OH group of donors	161
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	152
3-hydroxybutyrate dehydrogenase activity	2

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