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ONTOLOGY REPORT - ANNOTATIONS

Term:damaged DNA binding
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Accession:GO:0003684 term browser browse the term
Definition:Binding to damaged DNA.
Synonyms:related_synonym: DNA repair enzyme;   DNA repair protein


show annotations for term's descendants           Sort by:
damaged DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO
ISS		 (PMID:12524539), (PMID:14706345), (PMID:24703901)
GO_REF:0000024		 RGD
UniProt		 PMID:12524539 PMID:14706345 PMID:24703901 GO_REF:0000024 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aptx aprataxin enables ISO
IEA		 (PMID:14755728)
GO_REF:0000107		 RGD
Ensembl		 PMID:14755728 GO_REF:0000107 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855 		JBrowse link
G Aunip aurora kinase A and ninein interacting protein enables ISO
IEA
ISS		 (PMID:29042561)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29042561 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:146,722,329...146,734,924
Ensembl chr 5:146,722,337...146,736,501 		JBrowse link
G Brca1 BRCA1, DNA repair associated enables IEA
ISO		 GO_REF:0000107
(PMID:11934988)		 Ensembl
RGD		 PMID:11934988 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brme1 break repair meiotic recombinase recruitment factor 1 enables ISO (PMID:32345962), (PMID:32460033), (PMID:32463460) RGD PMID:32345962 PMID:32460033 PMID:32463460 NCBI chr19:23,990,049...24,011,774
Ensembl chr19:23,990,045...24,011,850 		JBrowse link
G Crebbp CREB binding protein enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:24939902)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24939902 GO_REF:0000024 GO_REF:0000107 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 enables ISO
IEA		 (PMID:12627958)
GO_REF:0000107		 RGD
Ensembl		 PMID:12627958 GO_REF:0000107 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965 		JBrowse link
G Cul4b cullin 4B contributes_to ISO (PMID:22334663) RGD PMID:22334663 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688 		JBrowse link
G Cyren cell cycle regulator of NHEJ enables IEA
ISO		 GO_REF:0000107
(PMID:30017584)		 Ensembl
RGD		 PMID:30017584 GO_REF:0000107 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602 		JBrowse link
G Dclre1a DNA cross-link repair 1A enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:255,569,911...255,589,815
Ensembl chr 1:255,569,919...255,589,678 		JBrowse link
G Dclre1b DNA cross-link repair 1B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Dclre1c DNA cross-link repair 1C enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 enables
contributes_to		 IMP
IEA
ISO		 GO_REF:0000107
(PMID:22334663)		 Ensembl
RGD		 PMID:22334663 PMID:12145536 GO_REF:0000107, RGD:632554 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 contributes_to ISO
IBA		 (PMID:22334663)
GO_REF:0000033		 RGD
GO_Central		 PMID:22334663 GO_REF:0000033 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ep300 E1A binding protein p300 enables ISO (PMID:24939902) RGD PMID:24939902 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit enables ISO
IBA		 (PMID:17720715)
GO_REF:0000033		 RGD
GO_Central		 PMID:17720715 GO_REF:0000033 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit enables ISO
IBA		 (PMID:11790111)
GO_REF:0000033		 RGD
GO_Central		 PMID:11790111 GO_REF:0000033 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease enables ISO (PMID:32821917) RGD PMID:32821917 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G H2ax H2A.X variant histone enables ISO (PMID:11934988) RGD PMID:11934988 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hmgb1 high mobility group box 1 enables ISO (PMID:17803946) RGD PMID:17803946 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 enables ISO (PMID:8226934) RGD PMID:8226934 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO (PMID:24550317) RGD PMID:24550317 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Msh2 mutS homolog 2 enables ISO MGI:1858055 (PMID:10545954), (PMID:7628020) RGD PMID:7628020 PMID:10545954 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 enables ISO MGI:1343961 (PMID:10545954) RGD PMID:10545954 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 enables ISO MGI:109519|MGI:2151803 (PMID:10545954) RGD PMID:10545954 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Nbn nibrin enables IEA
ISO
IBA		 GO_REF:0000107
(PMID:11934988)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:11934988 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Neil1 nei-like DNA glycosylase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
G Neil2 nei-like DNA glycosylase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:37,444,676...37,454,863
Ensembl chr15:37,445,381...37,454,863 		JBrowse link
G Neil3 nei-like DNA glycosylase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527 		JBrowse link
G Nthl1 nth-like DNA glycosylase 1 enables ISO (PMID:9927729) RGD PMID:9927729 NCBI chr10:13,655,791...13,661,958
Ensembl chr10:13,655,785...13,661,957 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase enables IDA
ISO		 (PMID:14706345) RGD PMID:14706345 PMID:9801319 RGD:729091 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 enables ISS
ISO		 GO_REF:0000024
(PMID:22683995), (PMID:26626479), (PMID:26626480), (PMID:27568560), (PMID:30675909), (PMID:32241924), (PMID:32358582), (PMID:37823600)		 UniProt
RGD		 PMID:22683995 PMID:26626479 PMID:26626480 PMID:27568560 PMID:30675909 More... GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 enables ISO (PMID:34108479) RGD PMID:34108479 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Pcna proliferating cell nuclear antigen enables ISO
ISS		 (PMID:24939902)
GO_REF:0000024		 RGD
UniProt		 PMID:24939902 GO_REF:0000024 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Polb DNA polymerase beta IDA RGD PMID:12388548 RGD:633643 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24939902)		 UniProt
Ensembl
RGD		 PMID:24939902 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Polh DNA polymerase eta enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723 		JBrowse link
G Poli DNA polymerase iota enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:64,116,774...64,134,373
Ensembl chr18:64,116,774...64,163,418 		JBrowse link
G Polk DNA polymerase kappa enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,313,563...23,320,702
Ensembl chr19:23,314,797...23,320,695 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein enables IEA GO_REF:0000002
GO_REF:0000104		 InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease enables ISO
IBA		 (PMID:18716619)
GO_REF:0000033		 RGD
GO_Central		 PMID:18716619 GO_REF:0000033 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rev1 REV1, DNA directed polymerase enables IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576 		JBrowse link
G Rpa1 replication protein A1 enables ISO
IBA		 (PMID:27723717), (PMID:27723720), (PMID:7700386)
GO_REF:0000033		 RGD
GO_Central		 PMID:7700386 PMID:27723717 PMID:27723720 GO_REF:0000033 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 enables ISO
ISS		 (PMID:27723717), (PMID:27723720), (PMID:7700386)
GO_REF:0000024		 RGD
UniProt		 PMID:7700386 PMID:27723717 PMID:27723720 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 enables ISO
IBA		 (PMID:7700386)
GO_REF:0000033		 RGD
GO_Central		 PMID:7700386 GO_REF:0000033 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpa3l1 replication protein A3 like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G Rps3 ribosomal protein S3 enables ISO (PMID:14706345), (PMID:15518571), (PMID:16737853), (PMID:17560175), (PMID:18610840) RGD PMID:14706345 PMID:15518571 PMID:16737853 PMID:17560175 PMID:18610840 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Sde2 SDE2 telomere maintenance homolog enables ISO
IEA		 (PMID:27906959)
GO_REF:0000107		 RGD
Ensembl		 PMID:27906959 GO_REF:0000107 NCBI chr13:92,578,843...92,595,142
Ensembl chr13:92,578,874...92,595,140 		JBrowse link
G Sirt6 sirtuin 6 enables ISO (PMID:31995034), (PMID:32538779) RGD PMID:31995034 PMID:32538779 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 enables ISO (PMID:11934988) RGD PMID:11934988 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Tp63 tumor protein p63 enables ISO (PMID:17122775) RGD PMID:17122775 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Trpc2 transient receptor potential cation channel subfamily C member 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,460,009...156,473,039
Ensembl chr 1:156,440,305...156,473,073 		JBrowse link
G Ung uracil-DNA glycosylase enables ISO (PMID:18973764) RGD PMID:18973764 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Xndc1 Xrcc1 N-terminal domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:156,440,284...156,460,609 JBrowse link
G Xpa XPA, DNA damage recognition and repair factor enables ISO
IBA		 (PMID:7700386)
GO_REF:0000033		 RGD
GO_Central		 PMID:7700386 GO_REF:0000033 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor enables ISO
IBA		 (PMID:12509299)
(PMID:22431748)
GO_REF:0000033		 RGD
GO_Central		 PMID:12509299 PMID:22431748 GO_REF:0000033 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
8-hydroxy-2'-deoxyguanosine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase enables ISO (PMID:19734539) RGD PMID:19734539 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Pot1 protection of telomeres 1 enables ISO (PMID:19734539) RGD PMID:19734539 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Wrn WRN RecQ like helicase enables ISO (PMID:19734539) RGD PMID:19734539 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
DNA-(abasic site) binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 enables ISO
ISS
IEA		 (PMID:9804798)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:9804798 GO_REF:0000024 GO_REF:0000107 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific enables ISO (PMID:30554877), (PMID:31235913), (PMID:32492421), (PMID:35450882), (PMID:36608669) RGD PMID:30554877 PMID:31235913 PMID:32492421 PMID:35450882 PMID:36608669 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
oxidized DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xrcc1 X-ray repair cross complementing 1 enables ISO (PMID:28002403) RGD PMID:28002403 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
oxidized purine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msh2 mutS homolog 2 contributes_to
enables		 ISO
IEA		 (PMID:11756455), (PMID:11801590)
GO_REF:0000107		 RGD
Ensembl		 PMID:11756455 PMID:11801590 GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 NOT|contributes_to ISO (PMID:11756455) RGD PMID:11756455 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 contributes_to ISO (PMID:11756455), (PMID:11801590) RGD PMID:11756455 PMID:11801590 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Mutyh mutY DNA glycosylase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase enables ISO (PMID:14706345) RGD PMID:14706345 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Recql4 RecQ like helicase 4 enables ISO (PMID:22039056) RGD PMID:22039056 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Rps3 ribosomal protein S3 enables ISO (PMID:14706345) RGD PMID:14706345 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
oxidized pyrimidine DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rps3 ribosomal protein S3 enables ISO (PMID:19656744) RGD PMID:19656744 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
single-strand break-containing DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aptx aprataxin enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:55,798,896...55,822,963
Ensembl chr 5:55,800,248...55,822,855 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20633
    binding 17721
      organic cyclic compound binding 6136
        nucleic acid binding 3845
          DNA binding 2276
            damaged DNA binding 68
              DNA-(abasic site) binding 2
              alkylated DNA binding + 0
              oxidized DNA binding + 11
              single-strand break-containing DNA binding 1
paths to the root