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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of systemic arterial blood pressure by renin-angiotensin
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Accession:GO:0003081 term browser browse the term
Definition:The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.
Synonyms:exact_synonym: blood pressure regulation by renin-angiotensin

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regulation of systemic arterial blood pressure by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:57,700,977...57,806,815 JBrowse link
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G AGT angiotensinogen involved_in IEA InterPro GO_REF:0000002 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G ENPEP glutamyl aminopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:58,363,816...58,448,231
Ensembl chr 7:58,364,445...58,447,574 		JBrowse link
G NOX1 NADPH oxidase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:89,182,636...89,210,176
Ensembl chr  X:89,183,264...89,209,298 		JBrowse link
angiotensin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:57,700,977...57,806,815 JBrowse link
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:8,324,094...8,354,491
Ensembl chr29:8,323,797...8,346,581 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:37,742,550...37,769,022
Ensembl chr  X:37,742,545...37,769,062 		JBrowse link
G CPA3 carboxypeptidase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:41,807,728...41,839,889
Ensembl chr15:41,807,727...41,839,819 		JBrowse link
G ENPEP glutamyl aminopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:58,363,816...58,448,231
Ensembl chr 7:58,364,445...58,447,574 		JBrowse link
G MME membrane metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:35,577,460...35,681,730
Ensembl chr15:35,580,714...35,633,914 		JBrowse link
G PRCP prolylcarboxypeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:74,021,085...74,104,623
Ensembl chr 1:74,018,409...74,104,515 		JBrowse link
G PREP prolyl endopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:68,406,298...68,536,166
Ensembl chr13:68,406,452...68,536,234 		JBrowse link
G REN renin involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:10617578) RGD
TreeGrafter
MGI
Ensembl		 PMID:10617578 PMID:21321306 GO_REF:0000107 GO_REF:0000118 RGD:5132599 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
angiotensin-mediated drinking behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:9622148 PMID:21281609 RGD:5129187 RGD:8549458 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:9437747 RGD:5147483 NCBI chr14:32,080,319...32,236,556
Ensembl chr14:32,083,615...32,233,596 		JBrowse link
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:10425188) MGI PMID:10425188 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (PMID:15998684) MGI PMID:15998684 NCBI chr  X:128,768,028...128,788,366
Ensembl chr  X:128,770,268...128,786,961 		JBrowse link
G RHOA ras homolog family member A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704 		JBrowse link
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:10425188)
(PMID:27217404) 		MGI PMID:10425188 PMID:27217404 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR2 angiotensin II receptor type 2 acts_upstream_of_or_within
involved_in 		ISO (PMID:10425188) MGI PMID:10425188
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (PMID:15998684) MGI PMID:15998684 NCBI chr  X:128,768,028...128,788,366
Ensembl chr  X:128,770,268...128,786,961 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:87,520,860...87,523,523
Ensembl chr13:87,521,947...87,523,098 		JBrowse link
G MRGPRD MAS related GPR family member D involved_in ISO (PMID:27217404) MGI PMID:27217404 NCBI chr 1:5,591,179...5,593,796 JBrowse link
brain renin-angiotensin system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:15499027), (PMID:9878677) MGI PMID:9878677 PMID:15499027 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:16585392)
(PMID:10880053) 		MGI PMID:10880053 PMID:16585392 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 acts_upstream_of_or_within ISO (PMID:9878677) MGI PMID:9878677
G MIF macrophage migration inhibitory factor ISO RGD PMID:17261648 RGD:1641980 NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) MGI PMID:16585392 NCBI chr13:94,141,648...94,605,750
Ensembl chr13:94,140,111...94,357,688 		JBrowse link
maintenance of blood vessel diameter homeostasis by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:41,957,826...42,002,776 JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,392,562...1,404,574
Ensembl chr16:1,392,571...1,404,636 		JBrowse link
negative regulation of glomerular filtration by angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103233451 cytochrome b-245 light chain ISO RGD PMID:17220186 RGD:2317863 NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750 		JBrowse link
negative regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456 		JBrowse link
positive regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G LOC103247947 olfactory receptor 51E2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:62,172,573...62,180,085
Ensembl chr 1:62,177,553...62,178,515 		JBrowse link
regulation of angiotensin levels in blood term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPA3 carboxypeptidase A3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:41,807,728...41,839,889
Ensembl chr15:41,807,727...41,839,819 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:25715999 RGD:401794570 NCBI chr 6:37,289,088...37,316,850 JBrowse link
G NDST2 N-deacetylase and N-sulfotransferase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:57,561,349...57,574,145
Ensembl chr 9:57,563,820...57,569,756 		JBrowse link
regulation of blood volume by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:9691085) MGI PMID:9691085 NCBI chr22:66,683,987...66,737,645
Ensembl chr22:66,691,177...66,736,690 		JBrowse link
G NKX2-1 NK2 homeobox 1 ISO RGD PMID:12730191 RGD:1600160 NCBI chr24:13,274,118...13,317,533
Ensembl chr24:13,310,846...13,317,056 		JBrowse link
G REN renin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
regulation of renal output by angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:11606482)
(PMID:9507198), (PMID:9852267) 		MGI PMID:9507198 PMID:9852267 PMID:11606482 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:12167595) MGI PMID:12167595 NCBI chr15:41,957,826...42,002,776 JBrowse link
regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:25715999 RGD:401794570 NCBI chr 6:37,289,088...37,316,850 JBrowse link
regulation of systemic arterial blood pressure by circulatory renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:12574102)
(PMID:10076178), (PMID:11606482), (PMID:7989296), (PMID:9507198), (PMID:9852267)
(PMID:9466969) 		MGI PMID:7989296 PMID:9466969 PMID:9507198 PMID:9852267 PMID:10076178 More... NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:9466969) MGI PMID:9466969 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 involved_in ISO (PMID:7477267) BHF-UCL PMID:7477267
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:11606482) MGI PMID:11606482 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:12167595) MGI PMID:12167595 NCBI chr15:41,957,826...42,002,776 JBrowse link
G COMT catechol-O-methyltransferase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in ISO (PMID:8901832) BHF-UCL PMID:8901832 NCBI chr12:86,907,173...87,367,935
Ensembl chr12:87,042,557...87,367,033 		JBrowse link
G SUCNR1 succinate receptor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:38,798,926...38,809,093
Ensembl chr15:38,797,962...38,809,017 		JBrowse link
renin-angiotensin regulation of aldosterone production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:10076178), (PMID:9852267) RGD
MGI		 PMID:9852267 PMID:10076178 PMID:21318332 RGD:5129178 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:12167595) RGD
MGI		 PMID:12167595 PMID:21318332 RGD:5129178 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:21318332 RGD:5129178
G REN renin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19826
    multicellular organismal process 7552
      system process 2248
        endocrine process 125
          regulation of systemic arterial blood pressure by hormone 52
            regulation of systemic arterial blood pressure by renin-angiotensin 35
              maintenance of blood vessel diameter homeostasis by renin-angiotensin + 8
              regulation of blood volume by renin-angiotensin + 11
              regulation of systemic arterial blood pressure by circulatory renin-angiotensin + 23
              regulation of systemic arterial blood pressure by local renal renin-angiotensin 0
Path 2
Term Annotations click to browse term
  biological_process 19826
    multicellular organismal process 7552
      system process 2248
        circulatory system process 600
          blood circulation 573
            regulation of blood pressure 226
              regulation of systemic arterial blood pressure 129
                regulation of systemic arterial blood pressure mediated by a chemical signal 63
                  regulation of systemic arterial blood pressure by hormone 52
                    regulation of systemic arterial blood pressure by renin-angiotensin 35
                      maintenance of blood vessel diameter homeostasis by renin-angiotensin + 8
                      regulation of blood volume by renin-angiotensin + 11
                      regulation of systemic arterial blood pressure by circulatory renin-angiotensin + 23
                      regulation of systemic arterial blood pressure by local renal renin-angiotensin 0
paths to the root