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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of heart rate by acetylcholine
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Accession:GO:0003063 term browser browse the term
Definition:The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.
Synonyms:related_synonym: negative regulation of heart contraction rate by acetylcholine



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negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in ISO
IEA
RGD
Ensembl
GO_Central
PMID:9316844 GO_REF:0000096 GO_REF:0000107 RGD:2303391 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28625
    biological regulation 13469
      regulation of biological quality 3591
        regulation of heart rate 117
          negative regulation of heart rate 16
            negative regulation of heart rate by acetylcholine 1
              G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
Path 2
Term Annotations click to browse term
  biological_process 28625
    multicellular organismal process 9117
      system process 3354
        circulatory system process 636
          blood circulation 606
            regulation of blood pressure 242
              regulation of systemic arterial blood pressure 144
                nervous system process involved in regulation of systemic arterial blood pressure 25
                  regulation of systemic arterial blood pressure by neurotransmitter 3
                    regulation of systemic arterial blood pressure by acetylcholine 2
                      negative regulation of heart rate by acetylcholine 1
                        G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
paths to the root