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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of heart rate by acetylcholine
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Accession:GO:0003063 term browser browse the term
Definition:The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.
Synonyms:related_synonym: negative regulation of heart contraction rate by acetylcholine


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negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22130
    biological regulation 12562
      regulation of biological quality 3377
        regulation of heart rate 122
          negative regulation of heart rate 16
            negative regulation of heart rate by acetylcholine 1
              G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
Path 2
Term Annotations click to browse term
  biological_process 22130
    multicellular organismal process 8226
      system process 2944
        circulatory system process 612
          blood circulation 586
            regulation of blood pressure 228
              regulation of systemic arterial blood pressure 132
                nervous system process involved in regulation of systemic arterial blood pressure 23
                  regulation of systemic arterial blood pressure by neurotransmitter 3
                    regulation of systemic arterial blood pressure by acetylcholine 2
                      negative regulation of heart rate by acetylcholine 1
                        G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate 0
paths to the root