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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of systemic arterial blood pressure mediated by a chemical signal
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Accession:GO:0003044 term browser browse the term
Definition:The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
Synonyms:exact_synonym: blood pressure regulation mediated by a chemical signal


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regulation of systemic arterial blood pressure mediated by a chemical signal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC2A5 solute carrier family 2 member 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478 		JBrowse link
acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOD2 superoxide dismutase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:16873728) Ensembl
MGI
BHF-UCL		 PMID:16873728 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
angiotensin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IC
IEA
IDA		 (PMID:1668266)
(PMID:11432860), (PMID:1320019), (PMID:4322742), (PMID:6270633)		 UniProt
Ensembl		 PMID:1320019 PMID:1668266 PMID:4322742 PMID:6270633 PMID:11432860 GO_REF:0000107 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 involved_in IC
IEA		 (PMID:10924499) BHF-UCL
Ensembl		 PMID:10924499 GO_REF:0000107 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IDA (PMID:12045255), (PMID:15746149) HGNC-UCL PMID:12045255 PMID:15746149 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848 		JBrowse link
G CMA1 chymase 1 involved_in TAS Reactome Reactome:R-HSA-2022383 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265 		JBrowse link
G CPA3 carboxypeptidase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:148,865,296...148,897,203
Ensembl chr 3:148,865,296...148,897,203 		JBrowse link
G CTSG cathepsin G involved_in TAS Reactome Reactome:R-HSA-2022411 NCBI chr14:24,573,518...24,576,250
Ensembl chr14:24,573,518...24,576,250 		JBrowse link
G CTSZ cathepsin Z involved_in TAS Reactome Reactome:R-HSA-2022381 NCBI chr20:58,995,185...59,007,254
Ensembl chr20:58,985,686...59,008,238 		JBrowse link
G ENPEP glutamyl aminopeptidase involved_in NAS
IEA		 (PMID:19608358) UniProt
Ensembl		 PMID:19608358 GO_REF:0000107 NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285 		JBrowse link
G MME membrane metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G PRCP prolylcarboxypeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:82,822,936...82,901,644
Ensembl chr11:82,822,936...82,970,584 		JBrowse link
G PREP prolyl endopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:105,273,218...105,403,082
Ensembl chr 6:105,273,218...105,454,062 		JBrowse link
G REN renin acts_upstream_of_or_within
involved_in		 ISO
IBA
TAS
IEA
IDA		 (PMID:10617578)
(PMID:12045255)		 RGD
MGI
GO_Central
Reactome
Ensembl
HGNC-UCL		 PMID:10617578 PMID:12045255 PMID:21321306 GO_REF:0000033 GO_REF:0000107 RGD:5132599 Reactome:R-HSA-2022403 Reactome:R-HSA-2022412 Reactome:R-HSA-2065357 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
angiotensin-mediated drinking behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 involved_in IMP (PMID:18258853) BHF-UCL PMID:18258853 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:9622148 PMID:21281609 RGD:5129187 RGD:8549458 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G TACR1 tachykinin receptor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9437747 GO_REF:0000107 RGD:5147483 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:10425188) MGI PMID:10425188 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (PMID:15998684) MGI PMID:15998684 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G RHOA ras homolog family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24335996) Ensembl
MGI		 PMID:24335996 GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:27217404)
(PMID:10425188)		 MGI PMID:10425188 PMID:27217404 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR2 angiotensin II receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10425188) Ensembl
MGI		 PMID:10425188 GO_REF:0000107 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (PMID:15998684) MGI PMID:15998684 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447 		JBrowse link
G MRGPRD MAS related GPR family member D involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:68,980,021...68,980,986
Ensembl chr11:68,980,021...68,980,986 		JBrowse link
brain renin-angiotensin system term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:15499027), (PMID:9878677) MGI PMID:9878677 PMID:15499027 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:16585392)
(PMID:10880053)		 MGI PMID:10880053 PMID:16585392 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9878677) Ensembl
MGI		 PMID:9878677 GO_REF:0000107 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:17261648 RGD:1641980 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) MGI PMID:16585392 NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451 		JBrowse link
endothelin maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECE1 endothelin converting enzyme 1 involved_in IDA (PMID:7805846) BHF-UCL PMID:7805846 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
maintenance of blood vessel diameter homeostasis by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in TAS
IDA		 (PMID:10406457)
(PMID:1567413)		 BHF-UCL
UniProt		 PMID:1567413 PMID:10406457 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IC
IDA		 (PMID:10993080)
(PMID:25913193), (PMID:26420482)		 BHF-UCL
UniProt		 PMID:10993080 PMID:25913193 PMID:26420482 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:1,742,871...1,755,265
Ensembl chr17:1,742,836...1,755,265 		JBrowse link
negative regulation of glomerular filtration by angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain ISO RGD PMID:17220186 RGD:2317863 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452 		JBrowse link
negative regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2R coagulation factor II thrombin receptor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12093905) Ensembl
MGI		 PMID:12093905 GO_REF:0000107 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G ADRA1D adrenoceptor alpha 1D acts_upstream_of_or_within ISO (PMID:12595294) MGI PMID:12595294 NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287 		JBrowse link
G DRD5 dopamine receptor D5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12486173) Ensembl
MGI		 PMID:12486173 GO_REF:0000107 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10358009), (PMID:11641423) Ensembl
MGI
GO_Central		 PMID:10358009 PMID:11641423 GO_REF:0000033 GO_REF:0000107 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10358009), (PMID:11641423) Ensembl
MGI
GO_Central		 PMID:10358009 PMID:11641423 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10358009) Ensembl
MGI
GO_Central		 PMID:10358009 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPM1 tropomyosin 1 involved_in ISS (PMID:17556658) BHF-UCL PMID:17556658 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
positive regulation of heart rate by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12782680) Ensembl
MGI		 PMID:12782680 GO_REF:0000107 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G ADRA1B adrenoceptor alpha 1B acts_upstream_of_or_within ISO (PMID:12782680) MGI PMID:12782680 NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012 		JBrowse link
G ADRB1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10358009), (PMID:8693001) Ensembl
MGI		 PMID:8693001 PMID:10358009 GO_REF:0000107 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
positive regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G OR51E2 olfactory receptor family 51 subfamily E member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:4,680,171...4,697,853
Ensembl chr11:4,680,171...4,697,854 		JBrowse link
positive regulation of the force of heart contraction by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:19133992 RGD:5129126 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
positive regulation of the force of heart contraction by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12595294) Ensembl
MGI		 PMID:12595294 GO_REF:0000107 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G ADRA1B adrenoceptor alpha 1B acts_upstream_of_or_within ISO (PMID:12595294) MGI PMID:12595294 NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012 		JBrowse link
G ADRB1 adrenoceptor beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7761854)
(PMID:8693001)		 Ensembl
MGI		 PMID:7761854 PMID:8693001 GO_REF:0000107 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
positive regulation of the force of heart contraction by norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:19133992 RGD:5129126 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
regulation of angiotensin levels in blood term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPA3 carboxypeptidase A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15173164) Ensembl
MGI		 PMID:15173164 GO_REF:0000107 NCBI chr 3:148,865,296...148,897,203
Ensembl chr 3:148,865,296...148,897,203 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:25715999 RGD:401794570 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G NDST2 N-deacetylase and N-sulfotransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15173164) Ensembl
MGI		 PMID:15173164 GO_REF:0000107 NCBI chr10:73,801,916...73,811,820
Ensembl chr10:73,801,911...73,811,798 		JBrowse link
regulation of blood volume by renal aldosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 (PMID:14614232)
(PMID:16118390)		 BHF-UCL
MGI		 PMID:14614232 PMID:16118390 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15718388 GO_REF:0000107 RGD:1625109 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 involved_in ISO (PMID:24206662) MGI PMID:24206662 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
regulation of blood volume by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in NAS (PMID:17159080) BHF-UCL PMID:17159080 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G DRD3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:9691085) MGI PMID:9691085 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G NKX2-1 NK2 homeobox 1 ISO RGD PMID:12730191 RGD:1600160 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G REN renin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10617578) Ensembl
MGI		 PMID:10617578 GO_REF:0000107 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
regulation of renal output by angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IC (PMID:1668266) BHF-UCL PMID:1668266 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G AGT angiotensinogen involved_in
acts_upstream_of_or_within		 NAS
ISO		 (PMID:17159080)
(PMID:11606482)
(PMID:9507198), (PMID:9852267)		 BHF-UCL
MGI		 PMID:9507198 PMID:9852267 PMID:11606482 PMID:17159080 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:12167595) MGI PMID:12167595 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
regulation of renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within ISO (PMID:17255527) MGI PMID:17255527 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:25715999 RGD:401794570 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
regulation of systemic arterial blood pressure by atrial natriuretic peptide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase involved_in IEA
IMP
ISS		 (PMID:22437503) Ensembl
UniProt		 PMID:22437503 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
G RASL10B RAS like family 10 member B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:35,731,639...35,743,521
Ensembl chr17:35,731,639...35,743,521 		JBrowse link
regulation of systemic arterial blood pressure by circulatory renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:12574102)
(PMID:9466969)
(PMID:10076178), (PMID:11606482), (PMID:7989296), (PMID:9507198), (PMID:9852267)		 MGI PMID:7989296 PMID:9466969 PMID:9507198 PMID:9852267 PMID:10076178 More... NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:9466969) MGI PMID:9466969 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 acts_upstream_of_or_within ISO (PMID:16118390) MGI PMID:16118390 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
regulation of systemic arterial blood pressure by endothelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECE1 endothelin converting enzyme 1 involved_in IC (PMID:7805846) BHF-UCL PMID:7805846 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EDN1 endothelin 1 involved_in IDA
IBA		 (PMID:2649896) BHF-UCL
GO_Central		 PMID:2649896 GO_REF:0000033 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN2 endothelin 2 involved_in IDA
IBA		 (PMID:2649896) BHF-UCL
GO_Central		 PMID:2649896 GO_REF:0000033 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683 		JBrowse link
G EDN3 endothelin 3 involved_in IDA
IBA		 (PMID:2649896) BHF-UCL
GO_Central		 PMID:2649896 GO_REF:0000033 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G NOS3 nitric oxide synthase 3 involved_in IMP (PMID:8999856) BHF-UCL PMID:8999856 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G RHOA ras homolog family member A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24335996) Ensembl
MGI		 PMID:24335996 GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
regulation of systemic arterial blood pressure by neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide ISO RGD PMID:17187876 RGD:597811014 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048 		JBrowse link
regulation of systemic arterial blood pressure by norepinephrine-epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10358008) Ensembl
MGI		 PMID:10358008 GO_REF:0000107 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
regulation of systemic arterial blood pressure by renin-angiotensin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IMP
IBA
IC		 (PMID:174834)
(PMID:1668266)		 BHF-UCL
GO_Central
UniProt		 PMID:174834 PMID:1668266 GO_REF:0000033 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 involved_in IC
IMP		 (PMID:10924499)
(PMID:18258853)		 BHF-UCL PMID:10924499 PMID:18258853 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AGT angiotensinogen involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IC (PMID:1378723) BHF-UCL PMID:1378723 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G ENPEP glutamyl aminopeptidase involved_in IDA
NAS		 (PMID:19608358)
(PMID:8346219)		 UniProt PMID:8346219 PMID:19608358 NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285 		JBrowse link
G NOX1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16386251) Ensembl
MGI		 PMID:16386251 GO_REF:0000107 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
regulation of systemic arterial blood pressure by vasopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVPR1A arginine vasopressin receptor 1A involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12486173) Ensembl
MGI
GO_Central		 PMID:12486173 GO_REF:0000033 GO_REF:0000107 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G AVPR1B arginine vasopressin receptor 1B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12486173) Ensembl
MGI
GO_Central		 PMID:12486173 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:206,106,936...206,117,388
Ensembl chr 1:206,106,936...206,117,699 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166 		JBrowse link
G DRD5 dopamine receptor D5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12486173) Ensembl
MGI		 PMID:12486173 GO_REF:0000107 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G OXTR oxytocin receptor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:8,741,269...8,769,613
Ensembl chr 3:8,750,381...8,769,628 		JBrowse link
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within ISO (PMID:11606482) MGI PMID:11606482 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
renin secretion into blood stream term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:12167595) MGI PMID:12167595 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G COMT catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19139376) Ensembl
MGI		 PMID:19139376 GO_REF:0000107 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G PCSK5 proprotein convertase subtilisin/kexin type 5 involved_in IEP (PMID:8901832) BHF-UCL PMID:8901832 NCBI chr 9:75,889,809...76,362,975
Ensembl chr 9:75,890,644...76,362,975 		JBrowse link
G SUCNR1 succinate receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18535668) Ensembl
MGI		 PMID:18535668 GO_REF:0000107 NCBI chr 3:151,873,643...151,884,619
Ensembl chr 3:151,873,643...151,884,619 		JBrowse link
renin-angiotensin regulation of aldosterone production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen acts_upstream_of_or_within
involved_in		 ISO
NAS		 (PMID:10076178), (PMID:9852267)
(PMID:17159080)		 RGD
MGI
BHF-UCL		 PMID:9852267 PMID:10076178 PMID:17159080 PMID:21318332 RGD:5129178 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within
involved_in		 ISO
NAS		 (PMID:12167595)
(PMID:17159080)		 RGD
MGI
BHF-UCL		 PMID:12167595 PMID:17159080 PMID:21318332 RGD:5129178 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:21318332 RGD:5129178 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G REN renin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19293336) Ensembl
MGI		 PMID:19293336 GO_REF:0000107 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27213
    biological regulation 13724
      regulation of biological quality 3686
        regulation of blood pressure 249
          regulation of systemic arterial blood pressure 136
            regulation of systemic arterial blood pressure mediated by a chemical signal 64
              regulation of systemic arterial blood pressure by epinephrine 0
              regulation of systemic arterial blood pressure by hormone + 53
              regulation of systemic arterial blood pressure by neurotransmitter + 3
              regulation of systemic arterial blood pressure by norepinephrine 0
              regulation of systemic arterial blood pressure by norepinephrine-epinephrine + 8
Path 2
Term Annotations click to browse term
  biological_process 27213
    multicellular organismal process 8840
      system process 2953
        circulatory system process 745
          blood circulation 661
            regulation of blood pressure 249
              regulation of systemic arterial blood pressure 136
                regulation of systemic arterial blood pressure mediated by a chemical signal 64
                  regulation of systemic arterial blood pressure by epinephrine 0
                  regulation of systemic arterial blood pressure by hormone + 53
                  regulation of systemic arterial blood pressure by neurotransmitter + 3
                  regulation of systemic arterial blood pressure by norepinephrine 0
                  regulation of systemic arterial blood pressure by norepinephrine-epinephrine + 8
paths to the root