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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of humoral immune response
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Accession:GO:0002921 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
Synonyms:exact_synonym: down regulation of humoral immune response;   downregulation of humoral immune response
 narrow_synonym: inhibition of humoral immune response


show annotations for term's descendants           Sort by:
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD59 CD59 molecule acts_upstream_of_or_within
involved_in 		ISO
IBA 		(PMID:10946279), (PMID:11471050) RGD
MGI
GO_Central		 PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000033 RGD:1600482 NCBI chr 2:27,186,587...27,207,303 JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 9:68,025,673...68,132,162 JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:149,309,482...149,382,286
Ensembl chr 2:149,309,540...149,382,282 		JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:28657829)
(PMID:6211481) 		RGD
UniProt		 PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chr 9:67,933,069...67,960,380 JBrowse link
G CD59 CD59 molecule acts_upstream_of_or_within ISO (PMID:10946279) MGI PMID:10946279 NCBI chr 2:27,186,587...27,207,303 JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chr13:124,938,469...125,028,440
Ensembl chr13:124,955,030...125,054,463 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule, complement regulatory protein involved_in IDA (PMID:9029106) AgBase PMID:9029106 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr10:19,420,680...19,551,941
Ensembl chr10:19,421,565...19,551,840 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:52,175,601...52,198,635
Ensembl chr  X:52,175,607...52,198,566 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:67,726,159...67,774,369
Ensembl chr 9:67,731,179...67,776,115 		JBrowse link
G C4BPA complement component 4 binding protein, alpha involved_in IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:67,815,544...67,827,509
Ensembl chr 9:67,815,340...67,827,407 		JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:67,716,205...67,725,785
Ensembl chr 9:67,716,283...67,725,783 		JBrowse link
G CD46 CD46 molecule, complement regulatory protein involved_in IDA
IBA 		(PMID:9029106) AgBase
GO_Central		 PMID:9029106 GO_REF:0000033 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G LOC100736569 membrane cofactor protein-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:68,136,576...68,186,756 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr10:19,420,680...19,551,941
Ensembl chr10:19,421,565...19,551,840 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,440,810...62,483,678 		JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:13,324,160...13,338,826
Ensembl chr 2:13,324,158...13,338,663 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chr 4:88,873,762...88,892,964 JBrowse link
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,307,370...5,312,117
Ensembl chr12:5,307,374...5,312,106 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    immune system process 2590
      immune response 1711
        negative regulation of immune response 204
          negative regulation of humoral immune response 17
            negative regulation of antimicrobial humoral response + 1
            negative regulation of complement activation + 13
            negative regulation of humoral immune response mediated by circulating immunoglobulin + 10
Path 2
Term Annotations click to browse term
  biological_process 18944
    biological regulation 13005
      regulation of biological process 12624
        negative regulation of biological process 5658
          negative regulation of immune system process 565
            negative regulation of immune response 204
              negative regulation of humoral immune response 17
                negative regulation of antimicrobial humoral response + 1
                negative regulation of complement activation + 13
                negative regulation of humoral immune response mediated by circulating immunoglobulin + 10
paths to the root