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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of humoral immune response
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Accession:GO:0002921 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
Synonyms:exact_synonym: down regulation of humoral immune response;   downregulation of humoral immune response
 narrow_synonym: inhibition of humoral immune response


show annotations for term's descendants           Sort by:
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59a CD59a antigen acts_upstream_of_or_within
involved_in 		IDA
IBA
ISO
IMP 		(PMID:11471050)
(PMID:17237428) 		MGI
GO_Central
BHF-UCL		 PMID:11471050 PMID:17237428 GO_REF:0000033 GO_REF:0000096 NCBI chr 2:103,926,177...103,945,755
Ensembl chr 2:103,926,146...103,945,699 		JBrowse link
G Cd59b CD59b antigen involved_in
acts_upstream_of_or_within 		ISO
IBA
IDA 		(PMID:10946279), (PMID:11471050) RGD
GO_Central
MGI		 PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000033 GO_REF:0000096 RGD:1600482 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534 		JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule, decay accelerating factor for complement involved_in ISO
ISS 		RGD
GO_Central
UniProt		 PMID:10929073 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 RGD:2326180 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481 		JBrowse link
G Cd55b CD55 molecule, decay accelerating factor for complement B involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 NCBI chr 1:130,316,263...130,350,831
Ensembl chr 1:130,316,274...130,350,746 		JBrowse link
G Cd59a CD59a antigen involved_in IDA (PMID:17237428) BHF-UCL PMID:17237428 NCBI chr 2:103,926,177...103,945,755
Ensembl chr 2:103,926,146...103,945,699 		JBrowse link
G Cd59b CD59b antigen acts_upstream_of_or_within IDA (PMID:10946279) MGI PMID:10946279 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in
acts_upstream_of_or_within 		ISO
IMP 		(PMID:10642554) RGD
GO_Central
MGI		 PMID:10642554 PMID:11861390 GO_REF:0000096 RGD:625470 NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894 		JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 antigen, complement regulatory protein involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IBA
ISO 		GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bp complement component 4 binding protein involved_in ISO
IBA 		GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369 		JBrowse link
G Cd46 CD46 antigen, complement regulatory protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:194,781,019...194,813,878
Ensembl chr 1:194,779,690...194,813,894 		JBrowse link
G Cr2 complement receptor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156 		JBrowse link
G Zp3r zona pellucida 3 receptor involved_in ISO
IBA 		GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc receptor, IgG, low affinity IIb acts_upstream_of_or_within IMP (PMID:12385742) MGI PMID:12385742 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Foxj1 forkhead box J1 involved_in IMP (PMID:16002694) BHF-UCL PMID:16002694 NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within IMP (PMID:9254656) MGI PMID:9254656 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28625
    immune system process 3186
      immune response 2239
        negative regulation of immune response 251
          negative regulation of humoral immune response 17
            negative regulation of antimicrobial humoral response + 0
            negative regulation of complement activation + 14
            negative regulation of humoral immune response mediated by circulating immunoglobulin + 9
Path 2
Term Annotations click to browse term
  biological_process 28625
    biological regulation 13469
      regulation of biological process 13028
        negative regulation of biological process 6110
          negative regulation of immune system process 646
            negative regulation of immune response 251
              negative regulation of humoral immune response 17
                negative regulation of antimicrobial humoral response + 0
                negative regulation of complement activation + 14
                negative regulation of humoral immune response mediated by circulating immunoglobulin + 9
paths to the root