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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of humoral immune response
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Accession:GO:0002920 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of a humoral immune response.

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regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477), (PMID:20709950) MGI PMID:10891477 PMID:20709950 NCBI chrNW_004624832:4,837,247...4,842,126
Ensembl chrNW_004624832:4,837,247...4,841,756 		JBrowse link
G Spns2 SPNS lysolipid transporter 2, sphingosine-1-phosphate acts_upstream_of_or_within
involved_in 		ISO (PMID:22664872)
(PMID:34260944) 		MGI
UniProt		 PMID:22664872 PMID:34260944 NCBI chrNW_004624786:7,065,992...7,103,944
Ensembl chrNW_004624786:7,066,142...7,102,501 		JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:28657829)
(PMID:6211481) 		UniProt
RGD		 PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chrNW_004624807:4,252,676...4,274,828 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chrNW_004624730:69,569,046...69,632,401
Ensembl chrNW_004624730:69,568,915...69,632,470 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624835:5,531,507...5,600,181
Ensembl chrNW_004624835:5,531,472...5,599,922 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO (PMID:17051150) UniProt PMID:17051150 NCBI chrNW_004624898:1,268,998...1,288,756
Ensembl chrNW_004624898:1,268,886...1,289,180 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpb complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624807:4,407,008...4,416,313
Ensembl chrNW_004624807:4,406,766...4,415,248 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624835:5,531,507...5,600,181
Ensembl chrNW_004624835:5,531,472...5,599,922 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serping1 serpin family G member 1 involved_in ISO (PMID:10946292) UniProt PMID:10946292 NCBI chrNW_004624864:3,091,397...3,103,084
Ensembl chrNW_004624864:3,091,083...3,103,090 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Foxj1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:6,025,756...6,030,487
Ensembl chrNW_004624801:6,025,793...6,030,486 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090 		JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:15611275) BHF-UCL PMID:15611275 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,795,405...3,804,192
Ensembl chrNW_004624832:3,796,532...3,803,973 		JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,774,837...3,778,646
Ensembl chrNW_004624832:3,775,252...3,778,432 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004624754:17,311,743...17,319,675
Ensembl chrNW_004624754:17,311,644...17,319,764 		JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23610393) UniProt PMID:23610393 NCBI chrNW_004624751:23,478,263...23,488,834
Ensembl chrNW_004624751:23,478,096...23,483,521 		JBrowse link
G Camp cathelicidin antimicrobial peptide ISO RGD PMID:18227173 RGD:438738460 NCBI chrNW_004624730:73,429,893...73,431,104 JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136 		JBrowse link
G Il17f interleukin 17F involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004624855:3,865,559...3,867,175
Ensembl chrNW_004624855:3,848,409...3,867,175 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G Mbl2 mannose binding lectin 2 ISO RGD PMID:9920905 RGD:4889148 NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297 		JBrowse link
G Phb1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:5,556,728...5,565,969
Ensembl chrNW_004624795:5,556,450...5,565,988 		JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) ARUK-UCL PMID:30548312 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
positive regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:10520991) BHF-UCL PMID:10520991 NCBI chrNW_004624795:2,777,766...2,787,664
Ensembl chrNW_004624795:2,779,627...2,788,897 		JBrowse link
G LOC101700274 HLA class II histocompatibility antigen, DM alpha chain involved_in ISO (PMID:11714799) BHF-UCL PMID:11714799 NCBI chrNW_004624754:23,752,352...23,765,319
Ensembl chrNW_004624754:23,762,051...23,765,593 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISO (PMID:19004505) UniProt PMID:19004505 NCBI chrNW_004624740:15,037,818...15,044,207
Ensembl chrNW_004624740:15,037,943...15,044,193 		JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in ISO (PMID:19004505) UniProt PMID:19004505 NCBI chrNW_004624775:12,903,145...12,910,048
Ensembl chrNW_004624775:12,902,697...12,910,149 		JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc fragment of IgE receptor II acts_upstream_of_or_within ISO (PMID:8041705) MGI PMID:8041705 NCBI chrNW_004624828:747,800...754,185
Ensembl chrNW_004624828:748,671...754,185 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624817:7,947,554...7,957,553
Ensembl chrNW_004624817:7,947,639...7,957,462 		JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:24,626,930...24,628,412
Ensembl chrNW_004624754:24,627,318...24,628,182 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8566034) MGI PMID:8566034 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624801:5,905,761...5,926,547
Ensembl chrNW_004624801:5,905,761...5,923,752 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624885:375,035...375,967 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624824:2,720,444...2,765,937
Ensembl chrNW_004624824:2,721,336...2,765,811 		JBrowse link
regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in ISO (PMID:33082341) UniProt PMID:33082341 NCBI chrNW_004624770:9,772,818...9,799,837
Ensembl chrNW_004624770:9,772,818...9,798,259 		JBrowse link
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within ISO (PMID:16129705) MGI PMID:16129705 NCBI chrNW_004624838:1,627,632...1,655,079
Ensembl chrNW_004624838:1,627,873...1,657,475 		JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624786:9,239,119...9,243,617
Ensembl chrNW_004624786:9,239,177...9,243,961 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004624807:4,252,676...4,274,828 JBrowse link
G Cd5l CD5 molecule like acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004624794:3,060,436...3,071,570
Ensembl chrNW_004624794:3,060,365...3,072,801 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:25284781)
(PMID:18947875) 		MGI
RGD		 PMID:12374811 PMID:18947875 PMID:25284781 RGD:628500 NCBI chrNW_004624798:3,332,549...3,414,435 JBrowse link
G Phb2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004624860:3,599,435...3,605,016
Ensembl chrNW_004624860:3,599,687...3,604,872 		JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624835:5,531,507...5,600,181
Ensembl chrNW_004624835:5,531,472...5,599,922 		JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H involved_in ISO (PMID:20378178), (PMID:28671664) ComplexPortal PMID:20378178 PMID:28671664 NCBI chrNW_004624798:3,332,549...3,414,435 JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:9892684) MGI PMID:9892684 NCBI chrNW_004624807:4,252,676...4,274,828 JBrowse link
regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17646
    immune system process 2290
      immune response 1438
        humoral immune response 176
          regulation of humoral immune response 43
            negative regulation of humoral immune response + 10
            positive regulation of humoral immune response + 22
            regulation of antimicrobial humoral response + 13
            regulation of complement activation + 16
            regulation of humoral immune response mediated by circulating immunoglobulin + 14
Path 2
Term Annotations click to browse term
  biological_process 17646
    biological regulation 11836
      regulation of biological process 11481
        regulation of immune system process 1485
          regulation of immune response 842
            regulation of humoral immune response 43
              negative regulation of humoral immune response + 10
              positive regulation of humoral immune response + 22
              regulation of antimicrobial humoral response + 13
              regulation of complement activation + 16
              regulation of humoral immune response mediated by circulating immunoglobulin + 14
paths to the root