Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of humoral immune response
go back to main search page
Accession:GO:0002920 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of a humoral immune response.


show annotations for term's descendants           Sort by:
regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477), (PMID:20709950) MGI PMID:10891477 PMID:20709950 NCBI chr 1:107,130,553...107,136,602
Ensembl chr 1:107,128,996...107,136,081 		JBrowse link
G SPNS2 SPNS lysolipid transporter 2, sphingosine-1-phosphate involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:22664872) Ensembl
MGI		 PMID:22664872 GO_REF:0000107 NCBI chr 5:30,494,355...30,527,669 JBrowse link
G SPNS3 SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:30,464,288...30,493,609
Ensembl chr 5:30,464,513...30,526,882 		JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD59 CD59 molecule involved_in
acts_upstream_of_or_within 		ISO
IBA 		(PMID:10946279), (PMID:11471050) RGD
GO_Central
MGI		 PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000033 RGD:1600482 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329 		JBrowse link
G LOC490269 complement receptor type 2 acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 7:6,456,238...6,480,672 JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:42,285,537...42,365,637
Ensembl chr 2:42,285,537...42,365,690 		JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule involved_in ISO (PMID:6211481)
(PMID:28657829) 		RGD
UniProt		 PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226 		JBrowse link
G CD59 CD59 molecule acts_upstream_of_or_within ISO (PMID:10946279) MGI PMID:10946279 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329 		JBrowse link
G LOC490269 complement receptor type 2 involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chr34:19,689,426...19,750,669
Ensembl chr34:19,691,630...19,750,587 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC490269 complement receptor type 2 involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr38:23,640,882...23,685,288
Ensembl chr38:23,639,616...23,685,304 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:50,839,979...50,881,684
Ensembl chr  X:50,803,330...50,881,618 		JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:6,239,036...6,268,934
Ensembl chr 7:6,241,102...6,268,910 		JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,224,962...6,236,925
Ensembl chr 7:6,225,188...6,236,918 		JBrowse link
G LOC102156626 membrane cofactor protein-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:6,552,121...6,581,316 JBrowse link
G LOC490269 complement receptor type 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr38:23,640,882...23,685,288
Ensembl chr38:23,639,616...23,685,304 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:36,654,328...36,695,775 JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:38,570,354...38,580,751
Ensembl chr18:38,570,607...38,581,665 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR2B Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FOXJ1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,512,898...4,517,764
Ensembl chr 9:4,513,628...4,517,756 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G LOC490269 complement receptor type 2 involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 7:6,456,238...6,480,672 JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLK2 kallikrein-related peptidase 2 involved_in ISO (PMID:18714013) UniProt PMID:18714013 NCBI chr 1:105,981,210...105,984,449
Ensembl chr 1:105,979,073...106,020,101 		JBrowse link
G KLK5 kallikrein related peptidase 5 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chr 1:105,914,040...105,922,639
Ensembl chr 1:105,914,460...105,922,296 		JBrowse link
G KLK7 kallikrein related peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:105,891,206...105,895,441 JBrowse link
G PGC progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chr12:10,425,137...10,435,129 JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,545,991...30,557,199
Ensembl chr22:30,547,271...30,555,510 		JBrowse link
G CAMP cathelicidin antimicrobial peptide ISO RGD PMID:18227173 RGD:438738460 NCBI chr20:40,790,823...40,792,781
Ensembl chr20:40,790,811...40,792,794 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL17A interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IL17F interleukin 17F involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:19,904,283...19,908,497
Ensembl chr12:19,904,126...19,908,619 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G MBL1 mannose binding lectin 1 ISO RGD PMID:9920905 RGD:4889148 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G PHB1 prohibitin 1 involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chr 9:25,525,711...25,536,722
Ensembl chr 9:25,526,649...25,536,722 		JBrowse link
positive regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
G DLA-DMA major histocompatibility complex, class II, DM alpha involved_in ISO (PMID:11714799) BHF-UCL PMID:11714799 NCBI chr12:2,516,974...2,534,085
Ensembl chr12:2,503,325...2,533,990 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:7,586,212...7,594,610
Ensembl chr 6:7,585,970...7,594,610 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:2,324,657...2,332,357
Ensembl chr 4:2,324,226...2,331,470 		JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCER2 Fc epsilon receptor II acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:52,451,637...52,460,045
Ensembl chr20:52,449,922...52,457,805 		JBrowse link
G HPX hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chr21:29,749,913...29,759,176
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G LOC100687459 GTPase IMAP family member 5 ISO RGD PMID:11934565 RGD:2303774 NCBI chr16:14,887,308...14,895,522 JBrowse link
G LTA lymphotoxin alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:1,070,608...1,073,053
Ensembl chr12:1,071,192...1,073,067 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVPL envoplakin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:4,610,834...4,630,704
Ensembl chr 9:4,608,782...4,630,445 		JBrowse link
G IVL involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chr17:61,714,470...61,716,961 JBrowse link
G PPL periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chr 6:36,498,562...36,542,101
Ensembl chr 6:36,491,561...36,624,532 		JBrowse link
regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:13,863,017...13,885,245
Ensembl chr 8:13,863,380...13,885,130 		JBrowse link
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:31,354,665...31,359,672
Ensembl chr 5:31,354,723...31,359,469 		JBrowse link
G CD55 CD55 molecule acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226 		JBrowse link
G CD59 CD59 molecule acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329 		JBrowse link
G CD5L CD5 molecule like acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr 7:40,516,190...40,526,528
Ensembl chr 7:40,516,190...40,526,528 		JBrowse link
G CFH complement factor H acts_upstream_of_or_within ISO (PMID:18947875)
(PMID:25284781) 		RGD
MGI		 PMID:12374811 PMID:18947875 PMID:25284781 RGD:628500 NCBI chr38:2,878,677...2,956,226 JBrowse link
G PHB2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109 		JBrowse link
G SUSD4 sushi domain containing 4 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr38:23,640,882...23,685,288
Ensembl chr38:23,639,616...23,685,304 		JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFH complement factor H involved_in ISO (PMID:20378178), (PMID:28671664) ComplexPortal PMID:20378178 PMID:28671664 NCBI chr38:2,878,677...2,956,226 JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule acts_upstream_of_or_within ISO (PMID:9892684) MGI PMID:9892684 NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226 		JBrowse link
regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22130
    immune system process 2648
      immune response 1728
        humoral immune response 248
          regulation of humoral immune response 51
            negative regulation of humoral immune response + 16
            positive regulation of humoral immune response + 24
            regulation of antimicrobial humoral response + 15
            regulation of complement activation + 20
            regulation of humoral immune response mediated by circulating immunoglobulin + 17
Path 2
Term Annotations click to browse term
  biological_process 22130
    biological regulation 12559
      regulation of biological process 12177
        regulation of immune system process 1633
          regulation of immune response 950
            regulation of humoral immune response 51
              negative regulation of humoral immune response + 16
              positive regulation of humoral immune response + 24
              regulation of antimicrobial humoral response + 15
              regulation of complement activation + 20
              regulation of humoral immune response mediated by circulating immunoglobulin + 17
paths to the root