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ONTOLOGY REPORT - ANNOTATIONS


Term:antimicrobial peptide production
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Accession:GO:0002775 term browser browse the term
Definition:The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.



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antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) RGD PMID:27427436 NCBI chr 1:84,124,766...84,132,481 JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) RGD PMID:20056603 NCBI chr 8:13,133,043...13,140,761 JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) RGD PMID:11248802 NCBI chr 8:13,133,043...13,140,761 JBrowse link
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:9,817,251...9,819,174 JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:34,555,832...34,596,281 JBrowse link
negative regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink5 serine peptidase inhibitor, Kazal type 5 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr18:36,264,452...36,333,143 JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) RGD PMID:18167348 NCBI chr19:34,555,832...34,596,281 JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk1c10 kallikrein 1-related peptidase C10 involved_in ISO (PMID:18714013) RGD PMID:18714013 NCBI chr 1:94,402,993...94,407,052 JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO (PMID:17012259) RGD PMID:17012259 NCBI chr 1:94,296,574...94,304,768 JBrowse link
G Klk7 kallikrein-related peptidase 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:17012259)
Ensembl
RGD
PMID:17012259 GO_REF:0000107 NCBI chr 1:94,267,170...94,271,361 JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) RGD PMID:12759353 NCBI chr 9:13,257,462...13,265,682 JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in IEA
ISO
GO_REF:0000107
(PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107 NCBI chr 9:30,640,844...30,644,331 JBrowse link
G Il17f interleukin 17F involved_in IEA
ISO
GO_REF:0000107
(PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482 JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:34,555,832...34,596,281 JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO MGI:1194898|MGI:96626 (PMID:27427436) RGD PMID:27427436 NCBI chr10:101,458,227...101,474,778 JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO MGI:107507|MGI:1194898 (PMID:27427436) RGD PMID:27427436 NCBI chr 2:180,842,307...180,854,646 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO MGI:107507|MGI:96626 (PMID:27427436) RGD PMID:27427436 NCBI chr10:10,450,919...10,496,575 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      production of molecular mediator of immune response 249
        antimicrobial peptide production 14
          antibacterial peptide production + 12
          antifungal peptide production + 0
          antimicrobial peptide biosynthetic process + 4
          antimicrobial peptide secretion + 1
          negative regulation of antimicrobial peptide production + 1
          positive regulation of antimicrobial peptide production + 7
          regulation of antimicrobial peptide production + 11
Path 2
Term Annotations click to browse term
  biological_process 20534
    response to stimulus 11012
      response to external stimulus 2781
        response to external biotic stimulus 1876
          response to other organism 1872
            defense response to other organism 1325
              defense response to symbiont 1099
                antimicrobial humoral response 162
                  antimicrobial humoral immune response mediated by antimicrobial peptide 119
                    antimicrobial peptide production 14
                      antibacterial peptide production + 12
                      antifungal peptide production + 0
                      antimicrobial peptide biosynthetic process + 4
                      antimicrobial peptide secretion + 1
                      negative regulation of antimicrobial peptide production + 1
                      positive regulation of antimicrobial peptide production + 7
                      regulation of antimicrobial peptide production + 11
paths to the root