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ONTOLOGY REPORT - ANNOTATIONS

Term:somatic recombination of T cell receptor gene segments
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Accession:GO:0002681 term browser browse the term
Definition:The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.
Synonyms:exact_synonym: somatic recombination of TCR gene segments


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T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO
IEA		 MGI:2663971 (PMID:12717433)
GO_REF:0000107		 RGD
Ensembl		 PMID:12717433 GO_REF:0000107 NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:98507 (PMID:9462507)
GO_REF:0000107		 RGD
Ensembl		 PMID:9462507 GO_REF:0000107 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:10911993) RGD PMID:10911993 NCBI chr16:86,220,345...86,228,930
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO
IEA		 MGI:2383951 (PMID:9768755)
GO_REF:0000107		 RGD
Ensembl		 PMID:9768755 GO_REF:0000107 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Tcf7 transcription factor 7 acts_upstream_of_or_within ISO MGI:96770 (PMID:9462507) RGD PMID:9462507 NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,423,445...36,453,535 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      somatic diversification of immune receptors 87
        somatic diversification of T cell receptor genes 5
          somatic recombination of T cell receptor gene segments 5
            T cell receptor V(D)J recombination 5
            somatic diversification of T cell receptor genes by N region addition 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      cellular developmental process 4833
        cell differentiation 4832
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 453
                    T cell differentiation 335
                      somatic diversification of T cell receptor genes 5
                        somatic recombination of T cell receptor gene segments 5
                          T cell receptor V(D)J recombination 5
                          somatic diversification of T cell receptor genes by N region addition 0
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