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ONTOLOGY REPORT - ANNOTATIONS

Term:somatic recombination of T cell receptor gene segments
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Accession:GO:0002681 term browser browse the term
Definition:The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.
Synonyms:exact_synonym: somatic recombination of TCR gene segments


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T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2663971 (PMID:12717433) 		Ensembl
RGD		 PMID:12717433 GO_REF:0000107 NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:132,598,968...132,691,301 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:98507 (PMID:9462507) 		Ensembl
RGD		 PMID:9462507 GO_REF:0000107 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:10911993) RGD PMID:10911993 NCBI chr16:86,220,345...86,228,930
Ensembl chr16:86,220,279...86,229,926 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2383951 (PMID:9768755) 		Ensembl
RGD		 PMID:9768755 GO_REF:0000107 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108 		JBrowse link
G Tcf7 transcription factor 7 acts_upstream_of_or_within ISO MGI:96770 (PMID:9462507) RGD PMID:9462507 NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      somatic diversification of immune receptors 90
        somatic diversification of T cell receptor genes 5
          somatic recombination of T cell receptor gene segments 5
            T cell receptor V(D)J recombination 5
            somatic diversification of T cell receptor genes by N region addition 0
Path 2
Term Annotations click to browse term
  biological_process 19315
    developmental process 7255
      cellular developmental process 4933
        cell differentiation 4932
          cell development 3418
            hemopoiesis 1096
              leukocyte differentiation 699
                mononuclear cell differentiation 559
                  lymphocyte differentiation 454
                    T cell differentiation 337
                      somatic diversification of T cell receptor genes 5
                        somatic recombination of T cell receptor gene segments 5
                          T cell receptor V(D)J recombination 5
                          somatic diversification of T cell receptor genes by N region addition 0
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