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ONTOLOGY REPORT - ANNOTATIONS

Term:pro-T cell differentiation
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Accession:GO:0002572 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
Synonyms:exact_synonym: pro-T lymphocyte differentiation


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pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO MGI:2384051 (PMID:7621074) RGD PMID:7621074 NCBI chr12:12,660,035...12,735,584
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO
IEA		 MGI:2181200|MGI:3696958|MGI:4418042 (PMID:19934022)
GO_REF:0000107		 RGD
Ensembl		 PMID:19934022 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA		 (PMID:30171019)
GO_REF:0000107		 RGD
Ensembl		 PMID:30171019 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO
IEA		 (PMID:22753936)
GO_REF:0000107		 RGD
Ensembl		 PMID:22753936 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:95,096,387...95,118,996 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      leukocyte activation 1082
        lymphocyte activation 875
          T cell activation 620
            T cell differentiation 335
              pro-T cell differentiation 4
                negative regulation of pro-T cell differentiation 0
                positive regulation of pro-T cell differentiation 1
                pro-T cell lineage commitment 0
                regulation of pro-T cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular developmental process 4833
        cell differentiation 4832
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 453
                    T cell differentiation 335
                      pro-T cell differentiation 4
                        negative regulation of pro-T cell differentiation 0
                        positive regulation of pro-T cell differentiation 1
                        pro-T cell lineage commitment 0
                        regulation of pro-T cell differentiation + 1
paths to the root