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ONTOLOGY REPORT - ANNOTATIONS

Term:somatic diversification of T cell receptor genes
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Accession:GO:0002568 term browser browse the term
Definition:The somatic process that results in the generation of sequence diversity of T cell receptor genes.
Synonyms:exact_synonym: somatic diversification of TCR genes

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T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12717433) MGI
Ensembl		 PMID:12717433 GO_REF:0000107 NCBI chr24:77,122,591...77,222,562
Ensembl chr24:77,122,689...77,221,454 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9462507) MGI
Ensembl		 PMID:9462507 GO_REF:0000107 NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110 		JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10911993) MGI
Ensembl		 PMID:10911993 GO_REF:0000107 NCBI chr 3:86,576,200...86,587,097
Ensembl chr 3:86,577,304...86,580,039 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9768755) Ensembl
MGI		 PMID:9768755 GO_REF:0000107 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541 		JBrowse link
G TCF7 transcription factor 7 acts_upstream_of_or_within ISO (PMID:9462507) MGI PMID:9462507 NCBI chr23:36,919,648...36,953,088
Ensembl chr23:36,919,745...36,951,192 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19822
    immune system process 2676
      somatic diversification of immune receptors 88
        somatic diversification of T cell receptor genes 5
          somatic diversification of T cell receptor genes by N region addition 0
          somatic recombination of T cell receptor gene segments + 5
Path 2
Term Annotations click to browse term
  biological_process 19822
    developmental process 6858
      cellular developmental process 4596
        cell differentiation 4595
          cell development 3274
            hemopoiesis 1055
              leukocyte differentiation 685
                mononuclear cell differentiation 556
                  lymphocyte differentiation 455
                    T cell differentiation 340
                      somatic diversification of T cell receptor genes 5
                        somatic diversification of T cell receptor genes by N region addition 0
                        somatic recombination of T cell receptor gene segments + 5
paths to the root