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ONTOLOGY REPORT - ANNOTATIONS

Term:somatic diversification of immune receptors via germline recombination within a single locus
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Accession:GO:0002562 term browser browse the term
Definition:The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.


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immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLB DNA polymerase beta acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:11,356,130...11,388,122
Ensembl chr17:11,356,129...11,388,821 		JBrowse link
G YY1 YY1 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:121,132,168...121,170,699
Ensembl chr 7:121,132,191...121,170,697 		JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYREN cell cycle regulator of NHEJ involved_in ISO (PMID:30017584), (PMID:31795137) UniProt PMID:30017584 PMID:31795137 NCBI chr18:14,127,724...14,133,486 JBrowse link
G FOXP1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892 		JBrowse link
G LIG4 DNA ligase 4 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716 		JBrowse link
G NHEJ1 non-homologous end joining factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:121,100,624...121,190,086
Ensembl chr15:121,100,628...121,194,042 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G TCF3 transcription factor 3 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:76,859,079...76,906,275
Ensembl chr 2:76,859,089...76,898,351 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chr 2:91,358,348...91,643,697
Ensembl chr 2:91,384,391...91,811,208 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AICDA activation induced cytidine deaminase acts_upstream_of_or_within
involved_in		 IEA
ISO		 (PMID:21518874) Ensembl
UniProt		 PMID:21518874 GO_REF:0000107 NCBI chr 5:62,777,236...62,787,342
Ensembl chr 5:62,777,352...62,787,369 		JBrowse link
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399 		JBrowse link
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,670,211...98,692,230
Ensembl chr 7:98,670,211...98,692,230 		JBrowse link
G CD40LG CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:51,783,537...51,808,898
Ensembl chr 6:51,783,478...51,798,984 		JBrowse link
G EXO1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chr10:15,317,555...15,360,593
Ensembl chr10:15,317,581...15,359,839 		JBrowse link
G EXOSC3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:238,536,341...238,541,756
Ensembl chr 1:238,536,345...238,541,333 		JBrowse link
G EXOSC6 exosome component 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:13,295,591...13,296,942
Ensembl chr 6:13,295,125...13,296,914 		JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716 		JBrowse link
G MLH1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G MSH6 mutS homolog 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238 		JBrowse link
G NBN nibrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:46,787,664...46,854,331
Ensembl chr 4:46,787,691...46,874,603 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:157,261,419...157,273,119
Ensembl chr13:157,261,419...157,272,688 		JBrowse link
G PCYT1A phosphate cytidylyltransferase 1A, choline involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:133,794,337...133,851,004
Ensembl chr13:133,818,761...133,850,996 		JBrowse link
G RNF168 ring finger protein 168 involved_in ISO (PMID:20080757) UniProt PMID:20080757 NCBI chr13:133,625,534...133,659,253 JBrowse link
G RNF8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:32,931,786...32,969,536
Ensembl chr 7:32,931,786...32,970,585 		JBrowse link
G SANBR SANT and BTB domain regulator of CSR involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:80,675,008...80,746,306
Ensembl chr 3:80,675,008...80,746,252 		JBrowse link
G SWAP70 switching B cell complex subunit SWAP70 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:49,721,120...49,805,262
Ensembl chr 2:49,719,669...49,805,049 		JBrowse link
G UNG uracil DNA glycosylase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:41,746,498...41,757,841
Ensembl chr14:41,746,502...41,757,807 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chr 2:91,358,348...91,643,697
Ensembl chr 2:91,384,391...91,811,208 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR6 C-C motif chemokine receptor 6 involved_in ISO (PMID:27174992) UniProt PMID:27174992 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821 		JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G IL4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:101,360,355...101,373,498
Ensembl chr15:101,360,094...101,373,526 		JBrowse link
G IL4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,075,807...34,084,384
Ensembl chr13:34,076,012...34,085,210 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:143,688,946...143,734,523
Ensembl chr 2:143,629,783...143,734,520 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EXOSC3 exosome component 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:238,536,341...238,541,756
Ensembl chr 1:238,536,345...238,541,333 		JBrowse link
G EXOSC6 exosome component 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:13,295,591...13,296,942
Ensembl chr 6:13,295,125...13,296,914 		JBrowse link
G HMCES 5-hydroxymethylcytosine binding, ES cell specific involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:71,732,311...71,752,296
Ensembl chr13:71,732,277...71,753,486 		JBrowse link
G KMT5B lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,710,510...4,768,237
Ensembl chr 2:4,711,023...4,765,979 		JBrowse link
G KMT5C lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,517,058...59,524,551
Ensembl chr 6:59,517,098...59,524,550 		JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,773,680...71,779,192
Ensembl chr 6:71,773,154...71,786,517 		JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:3,066,853...3,111,239
Ensembl chr18:3,066,848...3,111,240 		JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:769,518...832,036
Ensembl chr15:774,191...832,010 		JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:14,610,723...14,706,082
Ensembl chr17:14,610,817...14,707,872 		JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,005,599...88,121,155
Ensembl chr14:88,005,611...88,121,352 		JBrowse link
G TFRC transferrin receptor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:127,958,500...128,032,370
Ensembl chr 1:127,959,213...128,028,712 		JBrowse link
G TRAPPC13 trafficking protein particle complex subunit 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:44,146,574...44,186,346
Ensembl chr16:44,156,163...44,184,662 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLH1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:938,832...1,018,032
Ensembl chr 8:964,893...1,018,028 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within		 ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TNFSF13 TNF superfamily member 13 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:52,853,646...52,857,033
Ensembl chr12:52,853,904...52,857,029 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCF1 cardiotrophin like cytokine factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,142,315...5,152,750
Ensembl chr 2:5,143,313...5,152,692 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAD5 ATPase family AAA domain containing 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:42,874,705...42,920,438
Ensembl chr12:42,874,599...42,920,399 		JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:107,128,103...107,155,431
Ensembl chr15:107,128,203...107,162,935 		JBrowse link
G CD40 CD40 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL2 interleukin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G MLH1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837 		JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:3,066,853...3,111,239
Ensembl chr18:3,066,848...3,111,240 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G TBX21 T-box transcription factor 21 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:23,996,415...24,009,353
Ensembl chr12:23,996,415...24,009,355 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chr 3:73,752,115...73,831,158
Ensembl chr 3:73,752,118...73,831,035 		JBrowse link
G MIR181B-1 microRNA mir-181b-1 acts_upstream_of_or_within ISO (PMID:18762567) MGI PMID:18762567 NCBI chr10:21,696,492...21,696,571
Ensembl chr10:21,696,492...21,696,571 		JBrowse link
G MIR181B-2 microRNA mir-181b-2 acts_upstream_of_or_within ISO (PMID:18762567) MGI PMID:18762567 NCBI chr 1:265,499,111...265,499,196
Ensembl chr 1:265,499,108...265,499,196 		JBrowse link
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,916,716...44,940,732
Ensembl chr12:44,917,633...44,940,273 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:65,127,278...65,149,665
Ensembl chr 2:65,127,287...65,149,740 		JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:143,688,946...143,734,523
Ensembl chr 2:143,629,783...143,734,520 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:26,122,362...26,154,414
Ensembl chr14:26,122,386...26,154,781 		JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLH1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
G MSH3 mutS homolog 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:15238604) GO_Central
MGI		 PMID:15238604 GO_REF:0000033 NCBI chr 2:89,255,647...89,456,102
Ensembl chr 2:89,250,003...89,453,936 		JBrowse link
G MSH6 mutS homolog 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628 		JBrowse link
G UNG uracil DNA glycosylase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:41,746,498...41,757,841
Ensembl chr14:41,746,502...41,757,807 		JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLH1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757 		JBrowse link
G MSH2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585 		JBrowse link
T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:120,205,008...120,295,737
Ensembl chr 7:120,205,008...120,295,936 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G TCF7 transcription factor 7 acts_upstream_of_or_within ISO (PMID:9462507) MGI PMID:9462507 NCBI chr 2:136,422,740...136,456,323
Ensembl chr 2:136,422,940...136,457,910 		JBrowse link
V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552 		JBrowse link
G DCAF1 DDB1 and CUL4 associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:33,670,976...33,750,872
Ensembl chr13:33,670,977...33,750,772 		JBrowse link
G DCLRE1C DNA cross-link repair 1C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:46,820,016...46,863,848
Ensembl chr10:46,820,053...46,868,028 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:9166431) UniProt PMID:9166431 NCBI chr11:7,195,556...7,321,071 JBrowse link
G LIG1 DNA ligase 1 NOT|involved_in ISO (PMID:9809069) UniProt PMID:9809069 NCBI chr 6:53,620,483...53,660,020
Ensembl chr 6:53,620,483...53,686,562 		JBrowse link
G LIG3 DNA ligase 3 NOT|involved_in ISO (PMID:9809069) UniProt PMID:9809069 NCBI chr12:40,153,105...40,205,077
Ensembl chr12:40,153,397...40,183,622 		JBrowse link
G LIG4 DNA ligase 4 acts_upstream_of_or_within
involved_in		 IEA Ensembl GO_REF:0000107 NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G RAG1 recombination activating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 (PMID:2360047) Ensembl
MGI
GO_Central
UniProt
InterPro		 PMID:2360047 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 2:24,565,447...24,573,853
Ensembl chr 2:24,561,156...24,573,851 		JBrowse link
G RAG2 recombination activating 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:2360047) Ensembl
MGI
GO_Central		 PMID:2360047 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:24,547,605...24,553,944
Ensembl chr 2:24,547,644...24,558,403 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:10716994) MGI PMID:10716994 NCBI chr 2:91,358,348...91,643,697
Ensembl chr 2:91,384,391...91,811,208 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 acts_upstream_of_or_within ISO (PMID:10716994) MGI PMID:10716994 NCBI chr 5:6,903,496...6,929,162
Ensembl chr 5:6,903,495...6,929,052 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    immune system process 2587
      somatic diversification of immune receptors 86
        somatic diversification of immune receptors via germline recombination within a single locus 79
          V(D)J recombination + 21
          somatic recombination of T cell receptor gene segments + 5
          somatic recombination of immunoglobulin gene segments + 67
Path 2
Term Annotations click to browse term
  biological_process 18944
    cellular process 18487
      metabolic process 11698
        primary metabolic process 10347
          nucleobase-containing compound metabolic process 6273
            nucleic acid metabolic process 5762
              DNA metabolic process 910
                DNA recombination 319
                  somatic cell DNA recombination 79
                    somatic diversification of immune receptors via germline recombination within a single locus 79
                      V(D)J recombination + 21
                      somatic recombination of T cell receptor gene segments + 5
                      somatic recombination of immunoglobulin gene segments + 67
paths to the root