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ONTOLOGY REPORT - ANNOTATIONS


Term:production of molecular mediator of immune response
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Accession:GO:0002440 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:related_synonym: production of cellular mediator of immune response


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antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:27427436) Ensembl
MGI
PMID:27427436 GO_REF:0000107 NCBI chrNW_004624794:12,187,862...12,195,697
Ensembl chrNW_004624794:12,187,383...12,195,019
JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chrNW_004624878:345,038...364,986
Ensembl chrNW_004624878:345,038...361,652
JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004624878:345,038...364,986
Ensembl chrNW_004624878:345,038...361,652
JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7680896) Ensembl
MGI
PMID:7680896 GO_REF:0000107 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171
JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624933:507,879...558,357
Ensembl chrNW_004624933:506,254...554,015
JBrowse link
biosynthetic process of antibacterial peptides active against Gram-negative bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101705441 neutrophil elastase-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004625158:12,527...15,343 JBrowse link
G LOC101715199 neutrophil elastase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624828:7,720,020...7,722,842 JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24388753) MGI
Ensembl
PMID:24388753 GO_REF:0000107 NCBI chrNW_004624780:884,896...941,587 JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:23531880) MGI PMID:23531880 NCBI chrNW_004624734:3,846,753...3,875,294
Ensembl chrNW_004624734:3,846,765...3,875,294
JBrowse link
immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305
JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyren cell cycle regulator of NHEJ involved_in ISO (PMID:30017584), (PMID:31795137) UniProt PMID:30017584 PMID:31795137 NCBI chrNW_004624765:15,491,582...15,495,958
Ensembl chrNW_004624765:15,492,165...15,494,214
JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131
JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9823897) MGI
TreeGrafter
PMID:9823897 GO_REF:0000118 NCBI chrNW_004624793:3,699,394...3,706,591
Ensembl chrNW_004624793:3,699,506...3,706,073
JBrowse link
G Nhej1 non-homologous end joining factor 1 involved_in ISO (PMID:20558749) UniProt PMID:20558749 NCBI chrNW_004624823:5,859,157...5,944,573
Ensembl chrNW_004624823:5,864,003...5,946,583
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9768755) MGI
TreeGrafter
PMID:9768755 GO_REF:0000118 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305
JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16428437) MGI
TreeGrafter
PMID:16428437 GO_REF:0000118 NCBI chrNW_004624828:7,090,562...7,119,970
Ensembl chrNW_004624828:7,090,605...7,121,428
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9875844) MGI
TreeGrafter
PMID:9875844 GO_REF:0000118 NCBI chrNW_004624743:3,299,329...3,549,182
Ensembl chrNW_004624743:3,317,351...3,552,161
JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase acts_upstream_of_or_within
involved_in
ISO (PMID:17713479)
(PMID:21518874)
MGI
UniProt
PMID:17713479 PMID:21518874 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634
JBrowse link
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004624875:97,048...154,420
Ensembl chrNW_004624875:97,670...151,080
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:26,118,840...26,139,328
Ensembl chrNW_004624734:26,118,754...26,139,468
JBrowse link
G Cd40lg CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:15280420) MGI PMID:15280420 NCBI chrNW_004624907:2,288,380...2,298,909
Ensembl chrNW_004624907:2,288,423...2,298,373
JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004624771:12,215,957...12,230,908 JBrowse link
G Exosc3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624930:1,393,087...1,403,483
Ensembl chrNW_004624930:1,393,087...1,398,347
JBrowse link
G Exosc6 exosome component 6 involved_in ISO (PMID:21255825) UniProt PMID:21255825 NCBI chrNW_004624746:12,538,315...12,539,678
Ensembl chrNW_004624746:12,538,775...12,539,593
JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004624793:3,699,394...3,706,591
Ensembl chrNW_004624793:3,699,506...3,706,073
JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174)
(PMID:10430621)
Ensembl
MGI
PMID:10430621 PMID:12743174 GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16618598)
(PMID:17015724)
MGI
Ensembl
PMID:16618598 PMID:17015724 GO_REF:0000107 NCBI chrNW_004624738:29,083,696...29,108,792
Ensembl chrNW_004624738:29,083,692...29,108,792
JBrowse link
G Nbn nibrin involved_in ISO (PMID:15668383) UniProt PMID:15668383 NCBI chrNW_004624744:2,013,936...2,061,726
Ensembl chrNW_004624744:2,013,922...2,061,708
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037)
(PMID:31182790)
MGI PMID:25124037 PMID:31182790 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:61,417,030...61,466,028
Ensembl chrNW_004624730:61,418,013...61,466,016
JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:20080757) UniProt PMID:20080757 NCBI chrNW_004624730:61,592,967...61,627,585
Ensembl chrNW_004624730:61,591,943...61,627,170
JBrowse link
G Rnf8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:20,683,133...20,714,469
Ensembl chrNW_004624754:20,679,867...20,714,522
JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISO (PMID:33831416) UniProt PMID:33831416 NCBI chrNW_004624833:772,761...828,302
Ensembl chrNW_004624833:771,627...825,815
JBrowse link
G Swap70 switching B cell complex subunit SWAP70 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9642267) Ensembl
MGI
PMID:9642267 GO_REF:0000107 NCBI chrNW_004624766:1,794,430...1,887,927
Ensembl chrNW_004624766:1,794,530...1,885,472
JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724) MGI PMID:17015724 NCBI chrNW_004624747:12,261,546...12,275,229
Ensembl chrNW_004624747:12,261,623...12,274,859
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004624743:3,299,329...3,549,182
Ensembl chrNW_004624743:3,317,351...3,552,161
JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624785:12,190,802...12,203,924 JBrowse link
isotype switching to IgD isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdcsp follicular dendritic cell secreted protein acts_upstream_of_positive_effect ISO (PMID:17548624) MGI PMID:17548624 NCBI chrNW_004624890:1,641,993...1,645,026 JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689
JBrowse link
G Fdcsp follicular dendritic cell secreted protein acts_upstream_of_or_within_negative_effect ISO (PMID:17548624) MGI PMID:17548624 NCBI chrNW_004624890:1,641,993...1,645,026 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of
involved_in
ISO
IEA
(PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693
JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdcsp follicular dendritic cell secreted protein acts_upstream_of_or_within_negative_effect ISO (PMID:17548624) MGI PMID:17548624 NCBI chrNW_004624890:1,641,993...1,645,026 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004624763:22,645,807...22,818,592
Ensembl chrNW_004624763:22,646,231...22,718,294
JBrowse link
G Apoa1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136
JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248
JBrowse link
G Il10 interleukin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) BHF-UCL PMID:10443688 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISO (PMID:16020505) BHF-UCL PMID:16020505 NCBI chrNW_004624908:1,371,595...1,383,879
Ensembl chrNW_004624908:1,371,595...1,383,879
JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:8,211,232...8,224,020
Ensembl chrNW_004624794:8,211,094...8,221,866
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Ifnb1 interferon beta 1 ISO RGD PMID:10494101 RGD:401854240 NCBI chrNW_004624736:25,099,061...25,099,746 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624940:825,368...842,268
Ensembl chrNW_004624940:819,854...842,284
JBrowse link
G Il33 interleukin 33 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063) ParkinsonsUK-UCL PMID:19328063 NCBI chrNW_004624816:2,519,839...2,540,766 JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO (PMID:29536159) MGI PMID:29536159 NCBI chrNW_004624795:3,242,607...3,252,997 JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (PMID:26000965) UniProt PMID:26000965 NCBI chrNW_004624730:5,761,635...5,768,138
Ensembl chrNW_004624730:5,762,148...5,769,094
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004624774:1,245,587...1,353,253
Ensembl chrNW_004624774:1,303,773...1,353,253
JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO (PMID:11168643) MGI PMID:11168643 NCBI chrNW_004624828:3,305,913...3,309,983
Ensembl chrNW_004624828:3,307,635...3,310,547
JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) MGI PMID:24670807 NCBI chrNW_004624823:5,787,525...5,797,536
Ensembl chrNW_004624823:5,787,601...5,797,534
JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004624907:76,236...106,765
Ensembl chrNW_004624907:77,806...106,228
JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO (PMID:24882011) MGI PMID:24882011 NCBI chrNW_004624831:1,826,744...1,833,945
Ensembl chrNW_004624831:1,826,744...1,828,822
JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO (PMID:16926417) MGI PMID:16926417 NCBI chrNW_004624871:40,811...50,436
Ensembl chrNW_004624871:40,885...50,116
JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:12150927) BHF-UCL PMID:12150927 NCBI chrNW_004624802:2,042,486...2,098,921
Ensembl chrNW_004624802:2,047,409...2,098,545
JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004624784:14,549,926...14,564,028
Ensembl chrNW_004624784:14,549,834...14,563,398
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISS AgBase GO_REF:0000024 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624835:2,363,059...2,436,536
Ensembl chrNW_004624835:2,363,139...2,437,643
JBrowse link
G Tgfb3 transforming growth factor beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:25,717,011...25,739,942
Ensembl chrNW_004624734:25,716,972...25,739,199
JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004624739:11,352,040...11,354,019
Ensembl chrNW_004624739:11,352,141...11,352,809
JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004624847:3,730,126...3,774,338
Ensembl chrNW_004624847:3,730,291...3,773,773
JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:15950739) MGI PMID:15950739 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:16533754) MGI PMID:16533754 NCBI chrNW_004624740:8,624,231...8,688,747
Ensembl chrNW_004624740:8,624,205...8,690,800
JBrowse link
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 involved_in ISO (PMID:19564354) UniProt PMID:19564354 NCBI chrNW_004624908:588,925...591,033 JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004624756:821,738...831,482
Ensembl chrNW_004624756:823,947...831,376
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:11477403) UniProt PMID:11477403 NCBI chrNW_004624794:627,906...661,257 JBrowse link
G Smad7 SMAD family member 7 involved_in ISO (PMID:25642768) BHF-UCL PMID:25642768 NCBI chrNW_004624778:12,415,364...12,444,882
Ensembl chrNW_004624778:12,415,282...12,444,835
JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) MGI PMID:21383057 NCBI chrNW_004624754:5,664,899...5,686,675
Ensembl chrNW_004624754:5,665,445...5,686,692
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:19360123) UniProt PMID:19360123 NCBI chrNW_004624753:5,737,720...5,749,313
Ensembl chrNW_004624753:5,737,237...5,752,966
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004624736:25,099,061...25,099,746 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:23616576)
(PMID:10761931)
UniProt PMID:10761931 PMID:23616576 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,795,405...3,804,192
Ensembl chrNW_004624832:3,796,532...3,803,973
JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,774,837...3,778,646
Ensembl chrNW_004624832:3,775,252...3,778,432
JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004624754:17,311,743...17,319,675
Ensembl chrNW_004624754:17,311,644...17,319,764
JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
JBrowse link
G Il17f interleukin 17F involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004624855:3,865,559...3,867,175
Ensembl chrNW_004624855:3,848,409...3,867,175
JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11441110) UniProt PMID:11441110 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:8,140,629...8,155,313
Ensembl chrNW_004624794:8,140,629...8,155,258
JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISO (PMID:23665276) UniProt PMID:23665276 NCBI chrNW_004624794:8,200,101...8,202,145 JBrowse link
G Hk1 hexokinase 1 involved_in ISO (PMID:27374331) CAFA PMID:27374331 NCBI chrNW_004624754:3,594,478...3,656,231
Ensembl chrNW_004624754:3,591,090...3,659,760
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:19318092 RGD:401901206 NCBI chrNW_004624748:8,154,288...8,223,226
Ensembl chrNW_004624748:8,155,107...8,223,259
JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004624807:9,718,307...9,738,282
Ensembl chrNW_004624807:9,718,307...9,738,148
JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:29046356) ARUK-UCL PMID:29046356 NCBI chrNW_004624783:7,267,680...7,275,918
Ensembl chrNW_004624783:7,260,005...7,274,433
JBrowse link
G Lacc1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624748:11,150,678...11,194,794
Ensembl chrNW_004624748:11,187,316...11,194,841
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) ARUK-UCL PMID:22733818 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135
JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:27374331) CAFA PMID:27374331 NCBI chrNW_004624937:564,191...584,470 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) UniProt PMID:16260731 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:17346996) UniProt PMID:17346996 NCBI chrNW_004624832:5,246,328...5,254,247
Ensembl chrNW_004624832:5,246,895...5,253,207
JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004624736:31,345,774...31,473,727 JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21236258) MGI
TreeGrafter
PMID:21236258 GO_REF:0000118 NCBI chrNW_004624818:7,491,473...7,505,185 JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) UniProt PMID:24882218 NCBI chrNW_004624817:7,029,104...7,053,447
Ensembl chrNW_004624817:7,045,228...7,053,525
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004624822:1,824,378...1,843,599
Ensembl chrNW_004624822:1,825,238...1,841,288
JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19136564)
(PMID:27288407)
ARUK-UCL
UniProt
PMID:19136564 PMID:27288407 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910
JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:18454155) UniProt PMID:18454155 NCBI chrNW_004624761:14,733,912...14,831,428 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:16818757 RGD:1600784 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986
JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776) UniProt PMID:11714776 NCBI chrNW_004624794:447,572...472,700
Ensembl chrNW_004624794:447,584...472,778
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990
JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:28352114 RGD:151665126 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171
JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477) MGI PMID:10891477 NCBI chrNW_004624832:4,837,247...4,842,126
Ensembl chrNW_004624832:4,837,247...4,841,756
JBrowse link
G Cd86 CD86 molecule involved_in ISO (PMID:23241883) UniProt PMID:23241883 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712
JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:12023368) BHF-UCL PMID:12023368 NCBI chrNW_004624767:19,142,927...19,152,572
Ensembl chrNW_004624767:19,142,852...19,153,155
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISO (PMID:25222125) UniProt PMID:25222125 NCBI chrNW_004624739:21,187,581...21,193,345
Ensembl chrNW_004624739:21,187,581...21,193,337
JBrowse link
G Ephb2 EPH receptor B2 involved_in ISO (PMID:24803541) ARUK-UCL PMID:24803541 NCBI chrNW_004624764:7,421,818...7,599,800
Ensembl chrNW_004624764:7,421,862...7,593,482
JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:12438318) BHF-UCL PMID:12438318 NCBI chrNW_004624775:19,080,035...19,221,509
Ensembl chrNW_004624775:19,079,648...19,221,562
JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:3020690) CAFA PMID:3020690 NCBI chrNW_004624794:8,826,281...8,851,614
Ensembl chrNW_004624794:8,823,449...8,851,625
JBrowse link
G Hpx hemopexin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18641331) Ensembl
MGI
PMID:18641331 GO_REF:0000107 NCBI chrNW_004624817:7,947,554...7,957,553
Ensembl chrNW_004624817:7,947,639...7,957,462
JBrowse link
G Il10 interleukin 10 acts_upstream_of
involved_in
ISO
IEA
(PMID:22962438) ARUK-UCL
Ensembl
PMID:22962438 GO_REF:0000107 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO IgE production after infection
(PMID:15944273)
RGD
MGI
PMID:11573960 PMID:15944273 RGD:633067 NCBI chrNW_004624733:39,427,189...39,430,019
Ensembl chrNW_004624733:39,428,095...39,429,843
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chrNW_004624895:2,706,225...2,763,489
Ensembl chrNW_004624895:2,706,043...2,763,798
JBrowse link
G Il2 interleukin 2 acts_upstream_of
acts_upstream_of_or_within
ISO (PMID:22962438)
(PMID:1830926)
ARUK-UCL
MGI
PMID:1830926 PMID:22962438 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
JBrowse link
G Il21 interleukin 21 involved_in ISO (PMID:23045607) UniProt PMID:23045607 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304
JBrowse link
G Il33 interleukin 33 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624782:11,981,781...12,008,362 JBrowse link
G Il5 interleukin 5 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004624733:39,544,487...39,558,943
Ensembl chrNW_004624733:39,556,797...39,559,119
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322)
(PMID:23045607)
BHF-UCL
UniProt
PMID:3491322 PMID:23045607 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
JBrowse link
G Mzb1 marginal zone B and B1 cell specific protein involved_in ISO (PMID:19805154), (PMID:19805157) UniProt PMID:19805154 PMID:19805157 NCBI chrNW_004624743:32,192,264...32,194,848
Ensembl chrNW_004624743:32,192,251...32,194,376
JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:23241883) UniProt PMID:23241883 NCBI chrNW_004624795:5,556,728...5,565,969
Ensembl chrNW_004624795:5,556,450...5,565,988
JBrowse link
G Phb2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624860:3,599,435...3,605,016
Ensembl chrNW_004624860:3,599,687...3,604,872
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:1793833) UniProt PMID:1793833 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (PMID:10944490) BHF-UCL PMID:10944490 NCBI chrNW_004624737:4,795,054...4,800,830
Ensembl chrNW_004624737:4,791,628...4,800,989
JBrowse link
G Sash3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16227612) Ensembl
TreeGrafter
MGI
PMID:16227612 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624797:9,001,846...9,017,441
Ensembl chrNW_004624797:9,001,795...9,018,027
JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:24055037) UniProt PMID:24055037 NCBI chrNW_004624782:14,094,727...14,101,210
Ensembl chrNW_004624782:14,090,850...14,105,058
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:23333565 RGD:7245573 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:7749983) BHF-UCL PMID:7749983 NCBI chrNW_004624818:8,372,092...8,376,108
Ensembl chrNW_004624818:8,373,810...8,376,204
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:7749983) BHF-UCL PMID:7749983 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
G Vamp3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:24055037) UniProt PMID:24055037 NCBI chrNW_004624818:4,010,130...4,019,695
Ensembl chrNW_004624818:4,009,991...4,019,728
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154)
(PMID:12612580)
UniProt PMID:11460154 PMID:12612580 NCBI chrNW_004624747:5,123,085...5,128,465 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH17orf99 chromosome unknown C17orf99 homolog involved_in ISO (PMID:28978694) UniProt PMID:28978694 NCBI chrNW_004624801:7,668,551...7,678,531 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21255825) Ensembl
MGI
PMID:21255825 GO_REF:0000107 NCBI chrNW_004624930:1,393,087...1,403,483
Ensembl chrNW_004624930:1,393,087...1,398,347
JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004624746:12,538,315...12,539,678
Ensembl chrNW_004624746:12,538,775...12,539,593
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:31806351) UniProt PMID:31806351 NCBI chrNW_004624872:344,249...353,577
Ensembl chrNW_004624872:344,262...352,936
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004624767:18,654,682...18,716,087
Ensembl chrNW_004624767:18,655,193...18,716,252
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004624832:1,945,194...1,951,016
Ensembl chrNW_004624832:1,945,193...1,951,247
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004624818:1,274,553...1,286,750
Ensembl chrNW_004624818:1,282,082...1,286,997
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) UniProt PMID:20671152 NCBI chrNW_004624800:2,653,381...2,709,261
Ensembl chrNW_004624800:2,653,732...2,707,161
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23306439), (PMID:23333305), (PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 NCBI chrNW_004624866:5,619,758...5,680,165 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:6,630,746...6,766,314
Ensembl chrNW_004624741:6,638,889...6,721,118
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004624841:21,077...133,155
Ensembl chrNW_004624841:20,431...133,163
JBrowse link
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23760478)
(PMID:15077110), (PMID:15159415)
(PMID:23345425)
UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 NCBI chrNW_004624804:10,517,531...10,612,238
Ensembl chrNW_004624804:10,517,696...10,591,688
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chrNW_004624755:25,510,329...25,588,540
Ensembl chrNW_004624755:25,509,301...25,588,204
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within
involved_in
ISO
ISS
(PMID:14988498) MGI
AgBase
PMID:14988498 GO_REF:0000024 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14988498) MGI
TreeGrafter
PMID:14988498 GO_REF:0000118 NCBI chrNW_004624786:10,175,534...10,179,233
Ensembl chrNW_004624786:10,175,859...10,179,233
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:12023368) BHF-UCL PMID:12023368 NCBI chrNW_004624767:19,142,927...19,152,572
Ensembl chrNW_004624767:19,142,852...19,153,155
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004624875:97,048...154,420
Ensembl chrNW_004624875:97,670...151,080
JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chrNW_004624782:13,387,155...13,390,153
Ensembl chrNW_004624782:13,387,376...13,389,740
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chrNW_004624800:2,653,381...2,709,261
Ensembl chrNW_004624800:2,653,732...2,707,161
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family member 9 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17187069) Ensembl
MGI
PMID:17187069 GO_REF:0000107 NCBI chrNW_004624760:1,533,247...1,542,529
Ensembl chrNW_004624760:1,533,390...1,540,162
JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO (PMID:22002608) MGI PMID:22002608 NCBI chrNW_004624918:145,661...187,006 JBrowse link
G Cd36 CD36 molecule (CD36 blood group) acts_upstream_of_or_within ISO (PMID:16061696)
(PMID:15690042)
MGI PMID:15690042 PMID:16061696 NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333
JBrowse link
G Cd74 CD74 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514
JBrowse link
G Gprc5b G protein-coupled receptor class C group 5 member B involved_in ISO (PMID:23169819) UniProt PMID:23169819 NCBI chrNW_004624782:3,163,265...3,184,978
Ensembl chrNW_004624782:3,164,467...3,176,119
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) MGI PMID:9348310 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) ARUK-UCL PMID:22733818 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004624807:4,726,511...4,774,945
Ensembl chrNW_004624807:4,724,234...4,796,143
JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:12872135)
(PMID:10607756), (PMID:11067888), (PMID:12872135)
MGI PMID:10607756 PMID:11067888 PMID:12872135 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489
JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004624739:285,791...339,752
Ensembl chrNW_004624739:285,689...341,956
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051), (PMID:18261938)
(PMID:14560001), (PMID:15220916)
(PMID:15220916), (PMID:18261938)
(PMID:18261938)
MGI PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:18490713)
(PMID:11016935)
MGI PMID:11016935 PMID:18490713 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453
JBrowse link
G Panx1 pannexin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18490713) Ensembl
MGI
PMID:18490713 GO_REF:0000107 NCBI chrNW_004624735:38,766,973...38,823,284
Ensembl chrNW_004624735:38,766,981...38,819,092
JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of ISO (PMID:22041900) ARUK-UCL PMID:22041900 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Pycard PYD and CARD domain containing acts_upstream_of_or_within ISO (PMID:22002608) MGI PMID:22002608 NCBI chrNW_004624782:14,247,333...14,249,861
Ensembl chrNW_004624782:14,247,864...14,249,000
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098), (PMID:18261938) MGI PMID:11894098 PMID:18261938 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890
JBrowse link
G Rtn4 reticulon 4 involved_in ISO (PMID:19805174) UniProt PMID:19805174 NCBI chrNW_004624833:6,514,409...6,584,061 JBrowse link
G Sema7a semaphorin 7A (JohnMiltonHagen blood group) involved_in ISO (PMID:17377534) UniProt PMID:17377534 NCBI chrNW_004624781:221,821...244,854
Ensembl chrNW_004624781:221,812...248,185
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:22315447) UniProt PMID:22315447 NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946
JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004624755:26,045,617...26,049,951
Ensembl chrNW_004624755:26,045,493...26,053,476
JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12872135)
(PMID:12855817)
MGI PMID:12855817 PMID:12872135 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198
JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO (PMID:15690042) MGI PMID:15690042 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:10549626), (PMID:11067888)
(PMID:15690042)
MGI PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:12855817)
(PMID:18261938)
MGI PMID:12855817 PMID:18261938 NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10623794)
(PMID:18261938), (PMID:21609717)
(PMID:10549626), (PMID:10607756), (PMID:15661922)
(PMID:14691481)
Ensembl
MGI
PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link
G Tlr7 toll like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004624882:1,375,216...1,379,705 JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004624822:1,824,378...1,843,599
Ensembl chrNW_004624822:1,825,238...1,841,288
JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004624794:2,003,031...2,008,930
Ensembl chrNW_004624794:2,002,928...2,008,940
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034
JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:20100931) UniProt PMID:20100931 NCBI chrNW_004624761:14,733,912...14,831,428 JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (PMID:24586680) UniProt PMID:24586680 NCBI chrNW_004624825:1,098,915...1,141,373
Ensembl chrNW_004624825:1,097,432...1,141,446
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9000133) Ensembl
MGI
PMID:9000133 GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391
JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) UniProt PMID:17909078 NCBI chrNW_004624743:29,045,998...29,276,801
Ensembl chrNW_004624743:29,047,004...29,266,685
JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624865:898,850...927,375
Ensembl chrNW_004624865:898,850...928,091
JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624754:3,180,501...3,203,449
Ensembl chrNW_004624754:3,179,662...3,203,536
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624730:31,857,157...31,913,985
Ensembl chrNW_004624730:31,855,992...31,914,253
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624741:4,936,556...4,951,081
Ensembl chrNW_004624741:4,939,040...4,954,058
JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624736:37,134,718...37,204,543
Ensembl chrNW_004624736:37,133,059...37,197,218
JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198
JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:11756671) BHF-UCL PMID:11756671 NCBI chrNW_004624747:10,307,826...10,308,649
Ensembl chrNW_004624747:10,303,919...10,308,821
JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24658051) InterPro
MGI
Ensembl
PMID:24658051 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206
JBrowse link
G Clnk cytokine dependent hematopoietic cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624755:20,667,325...20,817,497 JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304
JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004624804:11,514,728...11,521,625 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004624807:4,252,676...4,274,828 JBrowse link
G Cd7 CD7 molecule involved_in ISO (PMID:10652336) UniProt PMID:10652336 NCBI chrNW_004624801:11,108,032...11,112,345 JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:16601243) CACAO PMID:16601243 NCBI chrNW_004624765:8,222,193...8,228,530
Ensembl chrNW_004624765:8,222,237...8,228,050
JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624799:3,554,644...3,623,317
Ensembl chrNW_004624799:3,554,678...3,622,289
JBrowse link
G Sash3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16227612) Ensembl
MGI
PMID:16227612 GO_REF:0000107 NCBI chrNW_004624797:9,001,846...9,017,441
Ensembl chrNW_004624797:9,001,795...9,018,027
JBrowse link
G Sectm1 secreted and transmembrane 1 involved_in ISO (PMID:22184754) UniProt PMID:22184754 NCBI chrNW_004624801:11,116,435...11,128,497 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) BHF-UCL PMID:9670042 PMID:18354165 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455
JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27671645) UniProt PMID:27671645 NCBI chrNW_004624749:2,491,162...2,504,580
Ensembl chrNW_004624749:2,491,156...2,506,110
JBrowse link
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004624749:6,875,934...6,909,702
Ensembl chrNW_004624749:6,875,750...6,909,734
JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004624749:6,661,142...6,737,988
Ensembl chrNW_004624749:6,708,522...6,739,871
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) UniProt PMID:9126961 NCBI chrNW_004624794:627,906...661,257 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931) UniProt PMID:10761931 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:11046035)
(PMID:8766544)
UniProt PMID:8766544 PMID:11046035 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922
JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) UniProt PMID:26774822 NCBI chrNW_004624798:2,621,604...2,844,370
Ensembl chrNW_004624798:2,622,379...2,838,775
JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15087456) Ensembl
MGI
PMID:15087456 GO_REF:0000107 NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392
JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:11159963) BHF-UCL PMID:11159963 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chrNW_004624937:564,191...584,470 JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (PMID:15987782) UniProt PMID:15987782 NCBI chrNW_004624818:7,758,192...7,846,950
Ensembl chrNW_004624818:7,759,770...7,847,208
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:19047684) UniProt PMID:19047684 NCBI chrNW_004624846:3,395,536...3,408,616
Ensembl chrNW_004624846:3,395,406...3,408,626
JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624801:5,905,761...5,926,547
Ensembl chrNW_004624801:5,905,761...5,923,752
JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624885:375,035...375,967 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004624824:2,720,444...2,765,937
Ensembl chrNW_004624824:2,721,336...2,765,811
JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22710871) Ensembl
MGI
PMID:22710871 GO_REF:0000107 NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151
JBrowse link
G Pkp3 plakophilin 3 involved_in ISO (PMID:26173741) UniProt PMID:26173741 NCBI chrNW_004624766:22,015,928...22,024,313
Ensembl chrNW_004624766:22,015,928...22,022,840
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO (PMID:28052249) ARUK-UCL PMID:28052249 NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710
JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004624739:1,663,916...1,668,258
Ensembl chrNW_004624739:1,664,432...1,666,867
JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19047410) Ensembl
MGI
PMID:19047410 GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856
JBrowse link
G Cd40lg CD40 ligand involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12958312) Ensembl
MGI
PMID:12958312 GO_REF:0000107 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338
JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO (PMID:26371324) MGI PMID:26371324 NCBI chrNW_004624819:587,739...680,618
Ensembl chrNW_004624819:643,045...680,684
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO (PMID:23223530) MGI PMID:23223530 NCBI chrNW_004624901:1,582,790...1,605,279 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
JBrowse link
G Traf2 TNF receptor associated factor 2 acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004624760:952,574...973,511
Ensembl chrNW_004624760:952,574...965,661
JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12958312) MGI
Ensembl
PMID:12958312 GO_REF:0000107 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455
JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:26371324)
(PMID:26320659)
MGI
Ensembl
PMID:26320659 PMID:26371324 GO_REF:0000107 NCBI chrNW_004624730:2,431,270...2,433,010
Ensembl chrNW_004624730:2,431,999...2,432,959
JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chrNW_004624762:4,727,834...4,847,779
Ensembl chrNW_004624762:4,724,813...4,847,416
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (PMID:21518874) UniProt PMID:21518874 NCBI chrNW_004624786:1,226,131...1,271,872
Ensembl chrNW_004624786:1,238,082...1,271,875
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16275384) MGI
Ensembl
PMID:16275384 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chrNW_004624901:1,274,753...1,288,783
Ensembl chrNW_004624901:1,274,840...1,287,861
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004624774:1,245,587...1,353,253
Ensembl chrNW_004624774:1,303,773...1,353,253
JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25310967) UniProt PMID:25310967 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173
JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide induced TNF factor acts_upstream_of_or_within ISO (PMID:16954198) MGI PMID:16954198 NCBI chrNW_004624782:6,715,584...6,748,873
Ensembl chrNW_004624782:6,720,497...6,747,317
JBrowse link
G Ube2j1 ubiquitin conjugating enzyme E2 J1 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004624799:4,811,686...4,838,708
Ensembl chrNW_004624799:4,811,649...4,841,511
JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calhm6 calcium homeostasis modulator family member 6 involved_in ISO (PMID:36861806) UniProt PMID:36861806 NCBI chrNW_004624856:1,989,913...1,992,496
Ensembl chrNW_004624856:1,986,546...1,992,578
JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chrNW_004624843:2,017,738...2,021,153 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710
JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:20656926) UniProt PMID:20656926 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926
JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in ISO (PMID:18722174) UniProt PMID:18722174 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634
JBrowse link
G Ctnnbl1 catenin beta like 1 involved_in ISO (PMID:18722174) UniProt PMID:18722174 NCBI chrNW_004624842:1,764,763...1,949,691
Ensembl chrNW_004624842:1,764,067...1,949,787
JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24388753) MGI
Ensembl
PMID:24388753 GO_REF:0000107 NCBI chrNW_004624780:884,896...941,587 JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in ISO (PMID:21518874) UniProt PMID:21518874 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634
JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004624771:12,215,957...12,230,908 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:35450882) UniProt PMID:35450882 NCBI chrNW_004624872:344,249...353,577
Ensembl chrNW_004624872:344,262...352,936
JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein involved_in ISO (PMID:23652018) UniProt PMID:23652018 NCBI chrNW_004624745:31,328,802...31,376,173
Ensembl chrNW_004624745:31,325,526...31,375,368
JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10092760), (PMID:10429667) MGI
TreeGrafter
PMID:10092760 PMID:10429667 GO_REF:0000118 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in
NOT|acts_upstream_of_or_within
IEA
ISO
(PMID:9607915)
(PMID:15494304)
(PMID:14568978)
(PMID:9697842), (PMID:9697843)
(PMID:9607916)
Ensembl
MGI
PMID:9607915 PMID:9607916 PMID:9697842 PMID:9697843 PMID:14568978 More... GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link
G Msh3 mutS homolog 3 NOT|acts_upstream_of_or_within ISO (PMID:10662804) MGI PMID:10662804 NCBI chrNW_004624743:1,461,952...1,581,524
Ensembl chrNW_004624743:1,461,077...1,581,180
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10662804), (PMID:15238604), (PMID:17015724)
(PMID:16618598)
MGI
Ensembl
PMID:10662804 PMID:15238604 PMID:16618598 PMID:17015724 GO_REF:0000107 NCBI chrNW_004624738:29,083,696...29,108,792
Ensembl chrNW_004624738:29,083,692...29,108,792
JBrowse link
G Nuggc nuclear GTPase, germinal center associated acts_upstream_of_or_within ISO (PMID:22833677) MGI PMID:22833677 NCBI chrNW_004624758:22,777,511...22,838,082
Ensembl chrNW_004624758:22,777,612...22,838,061
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10429667) MGI
TreeGrafter
PMID:10429667 GO_REF:0000118 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24388753) MGI
Ensembl
PMID:24388753 GO_REF:0000107 NCBI chrNW_004624780:884,896...941,587 JBrowse link
G Polm DNA polymerase mu acts_upstream_of_or_within ISO (PMID:15789338) MGI PMID:15789338 NCBI chrNW_004624740:7,932,179...7,939,133
Ensembl chrNW_004624740:7,932,064...7,938,365
JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:16172387), (PMID:16222339), (PMID:16890500) UniProt PMID:16172387 PMID:16222339 PMID:16890500 NCBI chrNW_004624731:26,649,606...26,808,098
Ensembl chrNW_004624731:26,649,727...26,807,222
JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29669924) UniProt PMID:29669924 NCBI chrNW_004624842:2,591,016...2,649,746
Ensembl chrNW_004624842:2,591,148...2,647,742
JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:15494304)
(PMID:17015724)
MGI PMID:15494304 PMID:17015724 NCBI chrNW_004624747:12,261,546...12,275,229
Ensembl chrNW_004624747:12,261,623...12,274,859
JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14568978)
(PMID:15494304)
(PMID:11828012)
(PMID:14563316), (PMID:15955838)
Ensembl
MGI
PMID:11828012 PMID:14563316 PMID:14568978 PMID:15494304 PMID:15955838 GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link
G Msh3 mutS homolog 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15238604) MGI
TreeGrafter
PMID:15238604 GO_REF:0000118 NCBI chrNW_004624743:1,461,952...1,581,524
Ensembl chrNW_004624743:1,461,077...1,581,180
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15238604) MGI
Ensembl
PMID:15238604 GO_REF:0000107 NCBI chrNW_004624738:29,083,696...29,108,792
Ensembl chrNW_004624738:29,083,692...29,108,792
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:15494304) MGI PMID:15494304 NCBI chrNW_004624747:12,261,546...12,275,229
Ensembl chrNW_004624747:12,261,623...12,274,859
JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12743174) Ensembl
TreeGrafter
MGI
PMID:12743174 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17638
    immune system process 2276
      production of molecular mediator of immune response 228
        antimicrobial peptide production + 13
        cytokine production involved in immune response + 119
        granulysin production 0
        granzyme A production + 0
        granzyme B production + 2
        immunoglobulin production + 110
        negative regulation of production of molecular mediator of immune response + 40
        perforin production 0
        positive regulation of production of molecular mediator of immune response + 140
        regulation of production of molecular mediator of immune response + 193
Path 2
Term Annotations click to browse term
  biological_process 17638
    cellular process 17218
      metabolic process 11007
        biosynthetic process 7918
          macromolecule biosynthetic process 7019
            gene expression 6590
              production of molecular mediator of immune response 228
                antimicrobial peptide production + 13
                cytokine production involved in immune response + 119
                granulysin production 0
                granzyme A production + 0
                granzyme B production + 2
                immunoglobulin production + 110
                negative regulation of production of molecular mediator of immune response + 40
                perforin production 0
                positive regulation of production of molecular mediator of immune response + 140
                regulation of production of molecular mediator of immune response + 193
paths to the root