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ONTOLOGY REPORT - ANNOTATIONS

Term:production of molecular mediator of immune response
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Accession:GO:0002440 term browser browse the term
Definition:The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
Comment:Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
Synonyms:related_synonym: production of cellular mediator of immune response

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antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals4 galectin 4 acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955468:694,831...701,623
Ensembl chrNW_004955468:694,873...701,535 		JBrowse link
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:20056603) MGI PMID:20056603 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
antibacterial peptide secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp7 matrix metallopeptidase 7 acts_upstream_of_or_within ISO (PMID:11248802) MGI PMID:11248802 NCBI chrNW_004955412:5,780,772...5,792,485
Ensembl chrNW_004955412:5,778,502...5,792,445 		JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase acts_upstream_of_or_within ISO (PMID:7680896) MGI PMID:7680896 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in ISO (PMID:20543113) MGI PMID:20543113 NCBI chrNW_004955411:36,328,152...36,363,614
Ensembl chrNW_004955411:36,326,926...36,363,288 		JBrowse link
biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
G Yy1 YY1 transcription factor involved_in ISO (PMID:23531880) MGI PMID:23531880 NCBI chrNW_004955438:21,341,374...21,377,674 JBrowse link
immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
immunoglobulin V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:9823897) MGI PMID:9823897 NCBI chrNW_004955404:3,606,077...3,615,193
Ensembl chrNW_004955404:3,606,077...3,615,193 		JBrowse link
G Nhej1 non-homologous end joining factor 1 involved_in ISO (PMID:20558749) UniProt PMID:20558749 NCBI chrNW_004955453:14,278,773...14,362,167
Ensembl chrNW_004955453:14,281,069...14,363,876 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO (PMID:9768755) MGI PMID:9768755 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within ISO (PMID:16428437) MGI PMID:16428437 NCBI chrNW_004955495:6,337,311...6,365,193
Ensembl chrNW_004955495:6,337,870...6,367,487 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:9875844) MGI PMID:9875844 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISO (PMID:20421391), (PMID:21572431) UniProt PMID:20421391 PMID:21572431 NCBI chrNW_004955523:42,365...66,103
Ensembl chrNW_004955523:42,218...66,103 		JBrowse link
G Cd40lg CD40 ligand involved_in ISO (PMID:7529792) UniProt PMID:7529792 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:15280420) MGI PMID:15280420 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522 		JBrowse link
G Exosc3 exosome component 3 involved_in ISO (PMID:21255825) UniProt PMID:21255825 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Exosc6 exosome component 6 involved_in ISO (PMID:21255825) UniProt PMID:21255825 NCBI chrNW_004955484:3,088,133...3,089,551
Ensembl chrNW_004955484:3,088,624...3,089,472 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004955404:3,606,077...3,615,193
Ensembl chrNW_004955404:3,606,077...3,615,193 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:10430621)
(PMID:12743174)		 MGI PMID:10430621 PMID:12743174 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:17015724)
(PMID:16618598)		 MGI PMID:16618598 PMID:17015724 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Nbn nibrin involved_in ISO (PMID:15668383) UniProt PMID:15668383 NCBI chrNW_004955417:6,840,916...6,880,479
Ensembl chrNW_004955417:6,839,312...6,880,133 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037)
(PMID:31182790)		 MGI PMID:25124037 PMID:31182790 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in ISO (PMID:19139091) UniProt PMID:19139091 NCBI chrNW_004955420:12,464,857...12,513,017
Ensembl chrNW_004955420:12,464,857...12,500,574 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (PMID:20080757) UniProt PMID:20080757 NCBI chrNW_004955420:12,656,815...12,676,836
Ensembl chrNW_004955420:12,657,272...12,676,426 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (PMID:20080757) UniProt PMID:20080757 NCBI chrNW_004955437:5,807,592...5,832,213
Ensembl chrNW_004955437:5,809,082...5,832,057 		JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISO (PMID:33831416) UniProt PMID:33831416 NCBI chrNW_004955424:22,728,802...22,785,374
Ensembl chrNW_004955424:22,728,802...22,785,374 		JBrowse link
G Swap70 switching B cell complex subunit SWAP70 acts_upstream_of_or_within ISO (PMID:9642267) MGI PMID:9642267 NCBI chrNW_004955414:25,385,648...25,444,743
Ensembl chrNW_004955414:25,385,007...25,444,913 		JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724) MGI PMID:17015724 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004955418:27,174,510...27,426,245
Ensembl chrNW_004955418:27,173,659...27,426,264 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (PMID:27174992) UniProt PMID:27174992 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004955403:3,062,724...3,073,419
Ensembl chrNW_004955403:3,063,133...3,073,419 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
negative regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004955417:30,199,508...30,386,695
Ensembl chrNW_004955417:30,198,842...30,386,266 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO (PMID:12458630) BHF-UCL PMID:12458630 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:12458630) BHF-UCL PMID:12458630 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753 		JBrowse link
G Il10 interleukin 10 involved_in ISO (PMID:10443688) BHF-UCL PMID:10443688 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10443688) BHF-UCL PMID:10443688 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jak3 Janus kinase 3 involved_in ISO (PMID:16020505) BHF-UCL PMID:16020505 NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643 		JBrowse link
negative regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO (PMID:20200274) ARUK-UCL PMID:20200274 NCBI chrNW_004955468:4,609,601...4,622,601
Ensembl chrNW_004955468:4,612,044...4,625,882 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Ifnb1 interferon beta 1 ISO RGD PMID:10494101 RGD:401854240 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272 		JBrowse link
G Il33 interleukin 33 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004955454:7,733,697...7,890,896
Ensembl chrNW_004955454:7,733,978...7,890,867 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:19328063) ParkinsonsUK-UCL PMID:19328063 NCBI chrNW_004955547:335,344...358,503
Ensembl chrNW_004955547:335,275...358,503 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO (PMID:29536159) MGI PMID:29536159 NCBI chrNW_004955451:14,571,707...14,579,890
Ensembl chrNW_004955451:14,571,556...14,579,948 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (PMID:26000965) UniProt PMID:26000965 NCBI chrNW_004955532:3,591,484...3,597,549
Ensembl chrNW_004955532:3,591,499...3,597,549 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
negative regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant acts_upstream_of_or_within ISO (PMID:11168643) MGI PMID:11168643 NCBI chrNW_004955495:2,418,113...2,421,181
Ensembl chrNW_004955495:2,418,364...2,421,538 		JBrowse link
G Atg9a autophagy related 9A acts_upstream_of_or_within ISO (PMID:24670807) MGI PMID:24670807 NCBI chrNW_004955453:14,203,798...14,214,760
Ensembl chrNW_004955453:14,206,065...14,213,729 		JBrowse link
G Axl AXL receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955555:189,445...218,509
Ensembl chrNW_004955555:189,174...218,565 		JBrowse link
G Cuedc2 CUE domain containing 2 acts_upstream_of_or_within ISO (PMID:24882011) MGI PMID:24882011 NCBI chrNW_004955485:7,969,389...7,977,073
Ensembl chrNW_004955485:7,975,190...7,976,875 		JBrowse link
G Epx eosinophil peroxidase acts_upstream_of_or_within ISO (PMID:16926417) MGI PMID:16926417 NCBI chrNW_004955451:4,818,809...4,828,913
Ensembl chrNW_004955451:4,818,809...4,828,913 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (PMID:12150927) BHF-UCL PMID:12150927 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004955412:20,275,767...20,287,414
Ensembl chrNW_004955412:20,275,917...20,287,414 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Tgfb3 transforming growth factor beta 3 involved_in ISO (PMID:20875417) DFLAT PMID:20875417 NCBI chrNW_004955438:33,129...55,180
Ensembl chrNW_004955438:29,415...55,180 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
G Twist2 twist family bHLH transcription factor 2 acts_upstream_of_or_within ISO (PMID:16831897) MGI PMID:16831897 NCBI chrNW_004955542:1,959,765...2,000,665
Ensembl chrNW_004955542:1,959,765...2,000,665 		JBrowse link
negative regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:15950739) MGI PMID:15950739 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:16533754) MGI PMID:16533754 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO (PMID:24658051) MGI PMID:24658051 NCBI chrNW_004955427:11,971,051...12,057,185
Ensembl chrNW_004955427:11,971,021...12,059,171 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453)
(PMID:23169781)		 UniProt PMID:15466453 PMID:23169781 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:11477403) UniProt PMID:11477403 NCBI chrNW_004955468:12,336,744...12,383,917
Ensembl chrNW_004955468:12,334,307...12,370,334 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO (PMID:25642768) BHF-UCL PMID:25642768 NCBI chrNW_004955402:34,028,184...34,058,949
Ensembl chrNW_004955402:34,028,063...34,058,291 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) MGI PMID:21383057 NCBI chrNW_004955437:19,716,466...19,743,428 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:19360123) UniProt PMID:19360123 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004955434:23,301,623...23,302,304 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:23616576)
(PMID:10761931)		 UniProt PMID:10761931 PMID:23616576 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) MGI PMID:18167348 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk5 kallikrein related peptidase 5 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,512,478...1,520,522
Ensembl chrNW_004955558:1,511,818...1,520,613 		JBrowse link
G Klk7 kallikrein related peptidase 7 involved_in ISO (PMID:17012259) UniProt PMID:17012259 NCBI chrNW_004955558:1,490,884...1,494,843
Ensembl chrNW_004955558:1,490,120...1,494,993 		JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004955437:8,142,523...8,153,044
Ensembl chrNW_004955437:8,142,661...8,151,339 		JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il17f interleukin 17F involved_in ISO (PMID:19144317) UniProt PMID:19144317 NCBI chrNW_004955411:5,852,767...5,859,208
Ensembl chrNW_004955411:5,852,767...5,859,208 		JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
positive regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11441110) UniProt PMID:11441110 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in ISO (PMID:23665276) UniProt PMID:23665276 NCBI chrNW_004955468:4,627,686...4,634,499 JBrowse link
G Hk1 hexokinase 1 involved_in ISO (PMID:27374331) CAFA PMID:27374331 NCBI chrNW_004955437:21,733,314...21,824,303
Ensembl chrNW_004955437:21,731,584...21,816,324 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO RGD PMID:19318092 RGD:401901206 NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945) UniProt PMID:28593945 NCBI chrNW_004955518:1,794,067...1,809,150
Ensembl chrNW_004955518:1,793,352...1,805,808 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) ARUK-UCL PMID:22733818 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:27374331) CAFA PMID:27374331 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:16260731) UniProt PMID:16260731 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) UniProt PMID:27288407 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:17346996) UniProt PMID:17346996 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
G Tek TEK receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20060382) MGI PMID:20060382 NCBI chrNW_004955472:7,633,790...7,748,130
Ensembl chrNW_004955472:7,633,721...7,748,386 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:21236258) MGI PMID:21236258 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218) UniProt PMID:24882218 NCBI chrNW_004955414:21,495,593...21,513,703
Ensembl chrNW_004955414:21,481,129...21,514,548 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
positive regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:18454155) UniProt PMID:18454155 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO RGD PMID:16818757 RGD:1600784 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:19136564) ARUK-UCL PMID:19136564 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:27288407) UniProt PMID:27288407 NCBI chrNW_004955467:10,547,706...10,578,355
Ensembl chrNW_004955467:10,547,294...10,578,387 		JBrowse link
positive regulation of granzyme A production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of granzyme B production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776) UniProt PMID:11714776 NCBI chrNW_004955468:12,532,937...12,559,859
Ensembl chrNW_004955468:12,534,064...12,559,434 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:23871208) UniProt PMID:23871208 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:18832695) BHF-UCL PMID:18832695 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:28352114 RGD:151665126 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO (PMID:10891477) MGI PMID:10891477 NCBI chrNW_004955559:1,465,937...1,471,249
Ensembl chrNW_004955559:1,465,937...1,471,249 		JBrowse link
G Cd86 CD86 molecule involved_in ISO (PMID:23241883) UniProt PMID:23241883 NCBI chrNW_004955427:21,375,820...21,436,767
Ensembl chrNW_004955427:21,375,794...21,435,874 		JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:12023368) BHF-UCL PMID:12023368 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 involved_in ISO (PMID:25222125) UniProt PMID:25222125 NCBI chrNW_004955410:12,814,993...12,820,852
Ensembl chrNW_004955410:12,814,479...12,822,777 		JBrowse link
G Ephb2 EPH receptor B2 involved_in ISO (PMID:24803541) ARUK-UCL PMID:24803541 NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO (PMID:16819554) MGI PMID:16819554 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 involved_in ISO (PMID:12438318) BHF-UCL PMID:12438318 NCBI chrNW_004955492:8,104,334...8,245,143
Ensembl chrNW_004955492:8,103,140...8,245,143 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:3020690) CAFA PMID:3020690 NCBI chrNW_004955468:3,980,999...4,007,553
Ensembl chrNW_004955468:3,980,999...4,008,652 		JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chrNW_004955414:22,158,654...22,169,133
Ensembl chrNW_004955414:22,156,819...22,169,631 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO IgE production after infection
(PMID:15944273)		 RGD
MGI		 PMID:11573960 PMID:15944273 RGD:633067 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO IgE production after infection RGD PMID:11573960 RGD:633067 NCBI chrNW_004955534:1,157,758...1,205,158
Ensembl chrNW_004955534:1,160,340...1,204,911 		JBrowse link
G Il2 interleukin 2 acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:22962438)
(PMID:1830926)		 ARUK-UCL
MGI		 PMID:1830926 PMID:22962438 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il21 interleukin 21 involved_in ISO (PMID:23045607) UniProt PMID:23045607 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
G Il33 interleukin 33 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Il5 interleukin 5 involved_in ISO (PMID:18268038) BHF-UCL PMID:18268038 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322)
(PMID:23045607)		 BHF-UCL
UniProt		 PMID:3491322 PMID:23045607 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Mzb1 marginal zone B and B1 cell specific protein involved_in ISO (PMID:19805154), (PMID:19805157) UniProt PMID:19805154 PMID:19805157 NCBI chrNW_004955418:1,170,365...1,172,581
Ensembl chrNW_004955418:1,170,365...1,172,581 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:23241883) UniProt PMID:23241883 NCBI chrNW_004955451:12,110,290...12,119,870
Ensembl chrNW_004955451:12,110,290...12,120,124 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO (PMID:23241883) UniProt PMID:23241883 NCBI chrNW_004955413:4,557,969...4,563,697
Ensembl chrNW_004955413:4,558,259...4,563,582 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (PMID:1793833) UniProt PMID:1793833 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (PMID:10944490) BHF-UCL PMID:10944490 NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:23333565 RGD:7245573 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:7749983) BHF-UCL PMID:7749983 NCBI chrNW_004955486:9,565,424...9,569,836
Ensembl chrNW_004955486:9,567,220...9,569,676 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:7749983) BHF-UCL PMID:7749983 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Vamp3 vesicle associated membrane protein 3 NOT|involved_in ISO (PMID:24055037) UniProt PMID:24055037 NCBI chrNW_004955486:5,103,228...5,112,157
Ensembl chrNW_004955486:5,103,106...5,112,176 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154)
(PMID:12612580)		 UniProt PMID:11460154 PMID:12612580 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH17orf99 chromosome unknown C17orf99 homolog involved_in ISO (PMID:28978694) UniProt PMID:28978694 NCBI chrNW_004955506:4,397,221...4,408,645 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9973465) BHF-UCL PMID:9973465 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) BHF-UCL PMID:12496423 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955484:3,088,133...3,089,551
Ensembl chrNW_004955484:3,088,624...3,089,472 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:31806351) UniProt PMID:31806351 NCBI chrNW_004955429:13,616,647...13,638,657
Ensembl chrNW_004955429:13,616,647...13,661,389 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004955422:17,626,606...17,684,890
Ensembl chrNW_004955422:17,647,530...17,682,132 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (PMID:28114273) UniProt PMID:28114273 NCBI chrNW_004955567:895,334...901,240
Ensembl chrNW_004955567:894,608...900,578 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955486:2,191,903...2,197,193
Ensembl chrNW_004955486:2,191,903...2,198,538 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) UniProt PMID:20671152 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23306439), (PMID:23333305), (PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 NCBI chrNW_004955440:16,977,710...17,047,809
Ensembl chrNW_004955440:16,979,042...17,041,748 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955415:16,180,074...16,282,937
Ensembl chrNW_004955415:16,180,051...16,280,864 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955510:6,021,477...6,114,745
Ensembl chrNW_004955510:6,075,510...6,114,898 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23760478)
(PMID:15077110), (PMID:15159415)
(PMID:23345425)		 UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 NCBI chrNW_004955416:9,962,736...10,035,433
Ensembl chrNW_004955416:9,962,897...10,035,278 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chrNW_004955514:1,084,522...1,162,624
Ensembl chrNW_004955514:1,069,085...1,162,624 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (PMID:12023368) BHF-UCL PMID:12023368 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chrNW_004955493:7,142,048...7,144,836
Ensembl chrNW_004955493:7,142,272...7,144,389 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) UniProt PMID:26744420 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (PMID:10430621) CAFA PMID:10430621 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
positive regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family member 9 acts_upstream_of_or_within ISO (PMID:17187069) MGI PMID:17187069 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) acts_upstream_of_or_within ISO (PMID:15690042)
(PMID:16061696)		 MGI PMID:15690042 PMID:16061696 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:19413900) BHF-UCL PMID:19413900 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Gprc5b G protein-coupled receptor class C group 5 member B involved_in ISO (PMID:23169819) UniProt PMID:23169819 NCBI chrNW_004955442:3,548,478...3,571,341
Ensembl chrNW_004955442:3,548,478...3,571,341 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:9348310) MGI PMID:9348310 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22733818) ARUK-UCL PMID:22733818 NCBI chrNW_004955452:9,335,481...9,358,177
Ensembl chrNW_004955452:9,334,587...9,358,444 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955406:42,231,858...42,276,477
Ensembl chrNW_004955406:42,231,858...42,276,477 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor acts_upstream_of_or_within ISO (PMID:10607756), (PMID:11067888), (PMID:12872135)
(PMID:12872135)		 MGI PMID:10607756 PMID:11067888 PMID:12872135 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:14560001), (PMID:15220916)
(PMID:15692051), (PMID:18261938)
(PMID:15220916), (PMID:18261938)
(PMID:18261938)		 MGI PMID:14560001 PMID:15220916 PMID:15692051 PMID:18261938 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:11016935)
(PMID:18490713)		 MGI PMID:11016935 PMID:18490713 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Panx1 pannexin 1 acts_upstream_of_or_within ISO (PMID:18490713) MGI PMID:18490713 NCBI chrNW_004955414:405,483...448,470
Ensembl chrNW_004955414:401,188...448,470 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of ISO (PMID:22041900) ARUK-UCL PMID:22041900 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098), (PMID:18261938) MGI PMID:11894098 PMID:18261938 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (PMID:19805174) UniProt PMID:19805174 NCBI chrNW_004955424:28,061,346...28,125,838 JBrowse link
G Sema7a semaphorin 7A (JohnMiltonHagen blood group) involved_in ISO (PMID:17377534) UniProt PMID:17377534 NCBI chrNW_004955450:3,401,732...3,424,547
Ensembl chrNW_004955450:3,401,777...3,423,363 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:22315447) UniProt PMID:22315447 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Spon2 spondin 2 acts_upstream_of_or_within ISO (PMID:14691481) MGI PMID:14691481 NCBI chrNW_004955514:598,840...603,390
Ensembl chrNW_004955514:596,829...604,051 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12872135)
(PMID:12855817)		 MGI PMID:12855817 PMID:12872135 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tirap TIR domain containing adaptor protein acts_upstream_of_or_within ISO (PMID:15690042) MGI PMID:15690042 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:15690042)
(PMID:10549626), (PMID:11067888)		 MGI PMID:10549626 PMID:11067888 PMID:15690042 PMID:18261938 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:18261938)
(PMID:12855817)		 MGI PMID:12855817 PMID:18261938 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:10623794)
(PMID:18261938), (PMID:21609717)
(PMID:10549626), (PMID:10607756), (PMID:15661922)
(PMID:14691481)		 MGI PMID:10549626 PMID:10607756 PMID:10623794 PMID:14691481 PMID:15661922 More... NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr7 toll like receptor 7 acts_upstream_of_or_within ISO (PMID:18261938) MGI PMID:18261938 NCBI chrNW_004955544:424,897...443,562
Ensembl chrNW_004955544:424,850...443,564 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18174455) UniProt PMID:18174455 NCBI chrNW_004955430:5,304,817...5,325,684
Ensembl chrNW_004955430:5,304,745...5,325,684 		JBrowse link
positive regulation of mast cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206 		JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:20100931) UniProt PMID:20100931 NCBI chrNW_004955447:16,149,014...16,226,151
Ensembl chrNW_004955447:16,148,605...16,226,734 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (PMID:24586680) UniProt PMID:24586680 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk4 calcium/calmodulin dependent protein kinase IV NOT|involved_in ISO (PMID:17909078) UniProt PMID:17909078 NCBI chrNW_004955418:3,664,352...3,887,175
Ensembl chrNW_004955418:3,664,479...3,887,175 		JBrowse link
G Ddx1 DEAD-box helicase 1 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955487:9,085,950...9,117,599
Ensembl chrNW_004955487:9,085,918...9,119,979 		JBrowse link
G Ddx21 DExD-box helicase 21 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955437:22,050,029...22,071,213
Ensembl chrNW_004955437:22,050,937...22,071,118 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955448:5,634,072...5,676,272
Ensembl chrNW_004955448:5,634,072...5,676,319 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672 		JBrowse link
G Rigi RNA sensor RIG-I involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:21703541) UniProt PMID:21703541 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
positive regulation of myeloid leukocyte cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:11756671) BHF-UCL PMID:11756671 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) UniProt PMID:17307798 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Cd226 CD226 molecule acts_upstream_of_or_within ISO (PMID:24658051) MGI PMID:24658051 NCBI chrNW_004955402:53,408,861...53,560,896
Ensembl chrNW_004955402:53,473,131...53,560,924 		JBrowse link
G Clnk cytokine dependent hematopoietic cell linker involved_in ISO (PMID:16439675) UniProt PMID:16439675 NCBI chrNW_004955549:2,166,891...2,375,902 JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
positive regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2-microglobulin involved_in ISO (PMID:24643698) BHF-UCL PMID:24643698 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Cd7 CD7 molecule involved_in ISO (PMID:10652336) UniProt PMID:10652336 NCBI chrNW_004955506:863,188...865,857 JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:16601243) CACAO PMID:16601243 NCBI chrNW_004955457:7,282,403...7,288,918
Ensembl chrNW_004955457:7,282,403...7,288,918 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165), (PMID:9670042) BHF-UCL PMID:9670042 PMID:18354165 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Traf2 TNF receptor associated factor 2 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9029087) BHF-UCL PMID:9029087 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A involved_in ISO (PMID:27671645) UniProt PMID:27671645 NCBI chrNW_004955470:3,951,010...3,964,391
Ensembl chrNW_004955470:3,950,750...3,965,750 		JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il18r1 interleukin 18 receptor 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:7,854,995...7,887,810
Ensembl chrNW_004955470:7,854,988...7,887,883 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 involved_in ISO (PMID:10653850) UniProt PMID:10653850 NCBI chrNW_004955470:7,685,498...7,703,374 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:9126961) UniProt PMID:9126961 NCBI chrNW_004955468:12,336,744...12,383,917
Ensembl chrNW_004955468:12,334,307...12,370,334 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (PMID:10761931) UniProt PMID:10761931 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9973465) BHF-UCL PMID:9973465 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:8766544)
(PMID:11046035)		 UniProt PMID:8766544 PMID:11046035 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) UniProt PMID:26774822 NCBI chrNW_004955406:34,021,508...34,241,735
Ensembl chrNW_004955406:34,027,046...34,241,737 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:15087456) MGI PMID:15087456 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:11159963) BHF-UCL PMID:11159963 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (PMID:15987782) UniProt PMID:15987782 NCBI chrNW_004955486:8,947,579...9,021,702
Ensembl chrNW_004955486:8,947,579...9,021,702 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISO (PMID:19047684) UniProt PMID:19047684 NCBI chrNW_004955487:1,988,226...2,001,731
Ensembl chrNW_004955487:1,987,405...2,001,731 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:9973465) BHF-UCL PMID:9973465 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Evpl envoplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955506:6,227,488...6,246,339
Ensembl chrNW_004955506:6,227,673...6,246,138 		JBrowse link
G Ivl involucrin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955592:522,730...525,728 JBrowse link
G Ppl periplakin acts_upstream_of_or_within ISO (PMID:27427436) MGI PMID:27427436 NCBI chrNW_004955442:12,581,918...12,627,407
Ensembl chrNW_004955442:12,581,879...12,626,516 		JBrowse link
regulation of cytokine production involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO (PMID:22710871) MGI PMID:22710871 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827 		JBrowse link
G Pkp3 plakophilin 3 involved_in ISO (PMID:26173741) UniProt PMID:26173741 NCBI chrNW_004955476:11,611,240...11,619,210
Ensembl chrNW_004955476:11,611,240...11,619,780 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO (PMID:28052249) ARUK-UCL PMID:28052249 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362 		JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004955410:30,497,953...30,503,444
Ensembl chrNW_004955410:30,500,276...30,502,735 		JBrowse link
regulation of dendritic cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr3 toll like receptor 3 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr9 toll like receptor 9 acts_upstream_of_or_within ISO (PMID:19047410) MGI PMID:19047410 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
regulation of immunoglobulin production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cd40lg CD40 ligand acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Cgas cyclic GMP-AMP synthase acts_upstream_of_or_within ISO (PMID:26371324) MGI PMID:26371324 NCBI chrNW_004955493:8,593,104...8,607,297 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO (PMID:23223530) MGI PMID:23223530 NCBI chrNW_004955415:33,040,868...33,062,753
Ensembl chrNW_004955415:33,043,918...33,063,567 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Traf2 TNF receptor associated factor 2 acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955513:4,964,692...4,984,359
Ensembl chrNW_004955513:4,967,984...4,983,987 		JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within ISO (PMID:12958312) MGI PMID:12958312 NCBI chrNW_004955422:9,925,765...9,950,354
Ensembl chrNW_004955422:9,932,680...9,949,100 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:26320659)
(PMID:26371324)		 MGI PMID:26320659 PMID:26371324 NCBI chrNW_004955532:533,877...535,767
Ensembl chrNW_004955532:533,877...535,767 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chrNW_004955424:16,338,546...16,449,074
Ensembl chrNW_004955424:16,336,228...16,448,766 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (PMID:21518874) UniProt PMID:21518874 NCBI chrNW_004955481:4,462,270...4,497,364
Ensembl chrNW_004955481:4,462,270...4,497,364 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chrNW_004955415:32,749,682...32,762,532
Ensembl chrNW_004955415:32,749,094...32,761,882 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25310967) UniProt PMID:25310967 NCBI chrNW_004955482:2,327,137...2,343,980 JBrowse link
regulation of macrophage cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Litaf lipopolysaccharide induced TNF factor acts_upstream_of_or_within ISO (PMID:16954198) MGI PMID:16954198 NCBI chrNW_004955442:7,054,418...7,084,973
Ensembl chrNW_004955442:7,077,823...7,083,437 		JBrowse link
G Ube2j1 ubiquitin conjugating enzyme E2 J1 acts_upstream_of_or_within ISO (PMID:24020373) MGI PMID:24020373 NCBI chrNW_004955411:16,076,647...16,091,554
Ensembl chrNW_004955411:16,074,551...16,091,570 		JBrowse link
regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calhm6 calcium homeostasis modulator family member 6 involved_in ISO (PMID:36861806) UniProt PMID:36861806 NCBI chrNW_004955526:319,920...321,985 JBrowse link
regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISO (PMID:28507030) UniProt PMID:28507030 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO (PMID:28052249) ARUK-UCL PMID:28052249 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (PMID:20656926) UniProt PMID:20656926 NCBI chrNW_004955559:1,539,036...1,581,800
Ensembl chrNW_004955559:1,546,365...1,581,712 		JBrowse link
somatic diversification of immunoglobulins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnbl1 catenin beta like 1 involved_in ISO (PMID:18722174) UniProt PMID:18722174 NCBI chrNW_004955445:18,809,389...18,975,858
Ensembl chrNW_004955445:18,809,023...18,976,255 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004955406:10,248,981...10,276,207
Ensembl chrNW_004955406:10,245,886...10,275,522 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (PMID:35450882) UniProt PMID:35450882 NCBI chrNW_004955429:13,616,647...13,638,657
Ensembl chrNW_004955429:13,616,647...13,661,389 		JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein involved_in ISO (PMID:23652018) UniProt PMID:23652018 NCBI chrNW_004955407:42,657,422...42,706,339
Ensembl chrNW_004955407:42,657,588...42,705,315 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:10092760), (PMID:10429667) MGI PMID:10092760 PMID:10429667 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 NOT|acts_upstream_of_or_within ISO (PMID:9607915)
(PMID:9697842), (PMID:9697843)
(PMID:15494304)
(PMID:14568978)
(PMID:9607916)		 MGI PMID:9607915 PMID:9607916 PMID:9697842 PMID:9697843 PMID:14568978 More... NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh3 mutS homolog 3 NOT|acts_upstream_of_or_within ISO (PMID:10662804) MGI PMID:10662804 NCBI chrNW_004955418:29,149,595...29,274,067
Ensembl chrNW_004955418:29,150,085...29,274,437 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:16618598)
(PMID:10662804), (PMID:15238604), (PMID:17015724)		 MGI PMID:10662804 PMID:15238604 PMID:16618598 PMID:17015724 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Nuggc nuclear GTPase, germinal center associated acts_upstream_of_or_within ISO (PMID:22833677) MGI PMID:22833677 NCBI chrNW_004955403:50,507,971...50,558,881
Ensembl chrNW_004955403:50,507,116...50,558,826 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in
acts_upstream_of_or_within		 ISO (PMID:9618520)
(PMID:10429667)		 CAFA
MGI		 PMID:9618520 PMID:10429667 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:24388753) MGI PMID:24388753 NCBI chrNW_004955536:542,179...595,198
Ensembl chrNW_004955536:540,836...595,198 		JBrowse link
G Polm DNA polymerase mu acts_upstream_of_or_within ISO (PMID:15789338) MGI PMID:15789338 NCBI chrNW_004955456:7,886,182...7,893,800
Ensembl chrNW_004955456:7,886,291...7,895,085 		JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:16172387), (PMID:16222339), (PMID:16890500) UniProt PMID:16172387 PMID:16222339 PMID:16890500 NCBI chrNW_004955427:20,779,332...20,895,094
Ensembl chrNW_004955427:20,778,952...20,894,989 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29669924) UniProt PMID:29669924 NCBI chrNW_004955422:24,714,103...24,780,672
Ensembl chrNW_004955422:24,735,161...24,778,830 		JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724)
(PMID:15494304)		 MGI PMID:15494304 PMID:17015724 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:11828012)
(PMID:15494304)
(PMID:14563316), (PMID:15955838)
(PMID:14568978)		 MGI PMID:11828012 PMID:14563316 PMID:14568978 PMID:15494304 PMID:15955838 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh3 mutS homolog 3 acts_upstream_of_or_within ISO (PMID:15238604) MGI PMID:15238604 NCBI chrNW_004955418:29,149,595...29,274,067
Ensembl chrNW_004955418:29,150,085...29,274,437 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:15238604) MGI PMID:15238604 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component acts_upstream_of_or_within ISO (PMID:11828012) MGI PMID:11828012 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:15494304) MGI PMID:15494304 NCBI chrNW_004955455:10,266,989...10,282,196
Ensembl chrNW_004955455:10,266,989...10,282,196 		JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12600
    immune system process 2043
      production of molecular mediator of immune response 219
        antimicrobial peptide production + 11
        cytokine production involved in immune response + 117
        granulysin production 0
        granzyme A production + 1
        granzyme B production + 3
        immunoglobulin production + 107
        negative regulation of production of molecular mediator of immune response + 41
        perforin production 0
        positive regulation of production of molecular mediator of immune response + 135
        regulation of production of molecular mediator of immune response + 189
Path 2
Term Annotations click to browse term
  biological_process 12600
    cellular process 12034
      metabolic process 7955
        biosynthetic process 5488
          macromolecule biosynthetic process 4806
            gene expression 4471
              production of molecular mediator of immune response 219
                antimicrobial peptide production + 11
                cytokine production involved in immune response + 117
                granulysin production 0
                granzyme A production + 1
                granzyme B production + 3
                immunoglobulin production + 107
                negative regulation of production of molecular mediator of immune response + 41
                perforin production 0
                positive regulation of production of molecular mediator of immune response + 135
                regulation of production of molecular mediator of immune response + 189
paths to the root