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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
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Accession:GO:0002433 term browser browse the term
Definition:An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
Synonyms:exact_synonym: immune response-regulating cell surface receptor signalling pathway involved in phagocytosis;   phagocytosis triggered by activation of immune response cell surface activating receptor


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Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G FCER2 Fc epsilon receptor II involved_in IDA (PMID:7544003) BHF-UCL PMID:7544003 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856 		JBrowse link
G IFNG interferon gamma involved_in IDA (PMID:7544003) BHF-UCL PMID:7544003 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G LIMK1 LIM domain kinase 1 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MYO1G myosin IG involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:44,962,662...44,979,015
Ensembl chr 7:44,962,662...44,979,088 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IMP (PMID:7544003) BHF-UCL PMID:7544003 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PLD2 phospholipase D2 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr17:4,807,152...4,823,430
Ensembl chr17:4,807,152...4,823,434 		JBrowse link
G PLPP4 phospholipid phosphatase 4 involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr10:120,456,954...120,592,065
Ensembl chr10:120,457,227...120,592,065 		JBrowse link
G PRKCD protein kinase C delta involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCE protein kinase C epsilon involved_in TAS Reactome Reactome:R-HSA-2029480 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 9:133,761,894...133,992,324
Ensembl chr 9:133,761,894...133,992,604 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
G YES1 YES proto-oncogene 1, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-2029480 Reactome:R-HSA-9664422 NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27213
    immune system process 3302
      immune effector process 837
        immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 25
          Fc-gamma receptor signaling pathway involved in phagocytosis + 25
Path 2
Term Annotations click to browse term
  biological_process 27213
    biological regulation 13724
      regulation of biological process 13268
        regulation of immune system process 1840
          regulation of immune response 1109
            immune response-regulating signaling pathway 641
              immune response-regulating cell surface receptor signaling pathway 393
                immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 25
                  Fc-gamma receptor signaling pathway involved in phagocytosis + 25
paths to the root