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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response to tumor cell
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Accession:GO:0002418 term browser browse the term
Definition:An immune system process that functions in the response of an organism to a tumor cell.



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immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO (PMID:22505472) RGD PMID:22505472 NCBI chr 2:174,754,629...174,765,136 JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10359807) RGD PMID:10359807 NCBI chr 1:78,372,798...78,398,932 JBrowse link
G Prf1 perforin 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:8164737)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8164737 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,789,040...29,794,550 JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (PMID:32839608) RGD PMID:32839608 NCBI chr 1:102,981,497...102,982,564 JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:23696226)
GO_REF:0000024
RGD
UniProt
PMID:23696226 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334 JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641 JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:90,324,312...90,340,627 JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:81,513,321...81,575,200 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS
IEA
(PMID:32818467)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:32818467 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:57,961,423...57,998,901 JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:236,526,215...236,549,956 JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(PMID:21469114), (PMID:28405502)
RGD PMID:21469114 PMID:28405502 PMID:32818467 NCBI chr 1:95,299,457...95,324,564 JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:94,418,786...94,431,945 JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS
(PMID:38377992)
GO_REF:0000024
RGD
UniProt
PMID:38377992 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134 JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:19016771 RGD:2313413 NCBI chr  X:140,164,341...140,176,057 JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:32188940) RGD PMID:32188940 NCBI chr 4:80,590,344...80,651,943 JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:22348394)
(PMID:21215706)
UniProt
GO_Central
RGD
PMID:21215706 PMID:22348394 GO_REF:0000024 GO_REF:0000033 NCBI chr11:91,559,087...91,573,982 JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS
IBA
GO_REF:0000024
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,039,371...78,049,353 JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr18:82,449,924...82,545,107 JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA
(PMID:15811952)
GO_REF:0000033
RGD
GO_Central
PMID:15811952 GO_REF:0000033 NCBI chr 8:41,340,117...41,377,381 JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA
(PMID:7903063)
GO_REF:0000107
RGD
Ensembl
PMID:7903063 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997 JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:29,390,300...29,405,194 JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:164,767,377...164,778,453 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:12913096)
GO_REF:0000033
RGD
GO_Central
PMID:12913096 GO_REF:0000033 NCBI chr 1:79,372,123...79,407,379 JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700 JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802 JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:25711213) RGD PMID:25711213 NCBI chr 2:184,340,820...184,383,421 JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA
(PMID:31959982)
GO_REF:0000107
RGD
Ensembl
PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985 JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020 JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) RGD PMID:7774619 NCBI chr20:48,655,549...48,661,786 JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO (PMID:30487606) RGD PMID:30487606 NCBI chr18:55,956,950...56,004,013 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) RGD PMID:10663613 NCBI chr 9:64,073,610...64,084,332 JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISO (PMID:33109719) RGD PMID:33109719 NCBI chr11:96,695,168...96,736,079 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 2:55,967,766...56,003,450 JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:30282837) RGD PMID:30282837 NCBI chr20:4,548,664...4,558,237 JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr12:20,744,500...20,772,828 JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:23108142)
UniProt
RGD
PMID:23108142 GO_REF:0000024 NCBI chr12:11,009,236...11,015,941 JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,261,656...3,265,548 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      immune response 2219
        immune response to tumor cell 39
          T cell mediated immune response to tumor cell + 17
          natural killer cell mediated immune response to tumor cell + 14
          negative regulation of immune response to tumor cell + 10
          positive regulation of immune response to tumor cell + 23
          regulation of immune response to tumor cell + 34
          tolerance induction to tumor cell + 0
Path 2
Term Annotations click to browse term
  biological_process 20534
    response to stimulus 11012
      response to biotic stimulus 1924
        response to tumor cell 55
          immune response to tumor cell 39
            T cell mediated immune response to tumor cell + 17
            natural killer cell mediated immune response to tumor cell + 14
            negative regulation of immune response to tumor cell + 10
            positive regulation of immune response to tumor cell + 23
            regulation of immune response to tumor cell + 34
            tolerance induction to tumor cell + 0
paths to the root