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ONTOLOGY REPORT - ANNOTATIONS

Term:pre-B cell receptor expression
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Accession:GO:0002330 term browser browse the term
Definition:The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.


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negative regulation of pre-B cell receptor expression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22949502) RGD PMID:22949502 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      cellular developmental process 4838
        pre-B cell receptor expression 1
          negative regulation of pre-B cell receptor expression 1
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      cellular developmental process 4838
        cell differentiation 4837
          cell development 3352
            hemopoiesis 1084
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 455
                    B cell differentiation 158
                      immature B cell differentiation 24
                        pre-B cell differentiation 14
                          pre-B cell receptor expression 1
                            negative regulation of pre-B cell receptor expression 1
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