Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:pre-B cell differentiation
go back to main search page
Accession:GO:0002329 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: pre-B lymphocyte differentiation
 related_synonym: pre-B cell development


show annotations for term's descendants           Sort by:
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO
IEA 		(PMID:21423173)
GO_REF:0000107 		RGD
Ensembl		 PMID:21423173 GO_REF:0000107 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:7795661), (PMID:9028339) RGD PMID:7795661 PMID:9028339 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within ISO MGI:3711150 (PMID:16819554) RGD PMID:16819554 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Lrrc8a leucine rich repeat containing 8 VRAC subunit A involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:14660746) 		UniProt
Ensembl
RGD		 PMID:14660746 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202 		JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3629917|MGI:3629918 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir18a microRNA 18a acts_upstream_of_or_within ISO MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir19a microRNA 19a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3619065|MGI:3629917|MGI:3629918 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629918 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir20a microRNA 20a acts_upstream_of_or_within ISO MGI:2676844|MGI:3618743|MGI:3619065|MGI:3629917|MGI:3629918 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir92a1 microRNA 92a-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
negative regulation of pre-B cell receptor expression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:22949502) RGD PMID:22949502 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:19448632) RGD PMID:19448632 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Rag1 recombination activating 1 involved_in IBA
ISO
IEA 		GO_REF:0000033
(PMID:19448632)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:19448632 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Rag2 recombination activating 2 involved_in ISO
IEA 		(PMID:19448632)
GO_REF:0000107 		RGD
Ensembl		 PMID:19448632 GO_REF:0000107 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3133
      leukocyte activation 1084
        lymphocyte activation 878
          lymphocyte differentiation 455
            B cell differentiation 158
              immature B cell differentiation 24
                pre-B cell differentiation 14
                  pre-B cell allelic exclusion 3
                  pre-B cell receptor expression + 1
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      cellular developmental process 4838
        cell differentiation 4837
          cell development 3352
            hemopoiesis 1084
              leukocyte differentiation 690
                mononuclear cell differentiation 556
                  lymphocyte differentiation 455
                    B cell differentiation 158
                      immature B cell differentiation 24
                        pre-B cell differentiation 14
                          pre-B cell allelic exclusion 3
                          pre-B cell receptor expression + 1
paths to the root