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ONTOLOGY REPORT - ANNOTATIONS


Term:natural killer cell activation involved in immune response
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Accession:GO:0002323 term browser browse the term
Definition:The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: NK cell activation during immune response;   natural killer cell activation during immune response



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natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776)
(PMID:15905190)
RGD PMID:11714776 PMID:15905190 NCBI chr13:86,583,727...86,606,902
Ensembl chr13:84,052,493...84,074,492
JBrowse link
G Cd244l1 CD244 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:86,547,250...86,569,026
Ensembl chr13:84,020,095...84,036,100
JBrowse link
G ENSRNOG00000065554 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 5:103,321,196...103,322,285 JBrowse link
G Ifna1 interferon, alpha 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:19130550)
GO_REF:0000033
RGD
GO_Central
PMID:19130550 GO_REF:0000033 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:103,097,356...103,097,925
JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:103,069,483...103,070,052
JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,640,546...108,641,115
Ensembl chr 5:103,524,733...103,525,302
JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,233,736...108,234,314 JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:49,732,073...49,734,281
JBrowse link
G Il12b interleukin 12B IMP RGD PMID:14960310 RGD:1600048 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G LOC120103158 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,494,288...108,494,937
Ensembl chr 5:103,378,593...103,379,147
JBrowse link
G LOC120103159 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,523,067...108,523,627
Ensembl chr 5:103,407,283...103,407,837
JBrowse link
G LOC120103160 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,542,177...108,542,731
Ensembl chr 5:103,426,387...103,426,941
JBrowse link
G LOC120103161 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,557,096...108,557,970
Ensembl chr 5:103,441,540...103,442,094
JBrowse link
G LOC120103162 interferon alpha-1-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,571,170...108,571,724
Ensembl chr 5:103,455,380...103,455,934
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO
IEA
(PMID:24760828)
GO_REF:0000107
RGD
Ensembl
PMID:24760828 GO_REF:0000107 NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:25786175), (PMID:28652325) RGD PMID:25786175 PMID:28652325 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 acts_upstream_of_or_within ISO (PMID:31024568) RGD PMID:31024568 NCBI chr15:46,117,211...46,145,258
Ensembl chr15:41,942,381...41,969,862
JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (PMID:32839608), (PMID:33911019) RGD PMID:32839608 PMID:33911019 NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO
IEA
MGI:1856656 (PMID:11266473)
GO_REF:0000107
RGD
Ensembl
PMID:11266473 GO_REF:0000107 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080), (PMID:23190531) RGD PMID:23042080 PMID:23190531 NCBI chr 1:9,111,216...9,140,227
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Unc13d unc-13 homolog D acts_upstream_of_or_within ISO MGI:3628822 (PMID:17420270) RGD PMID:17420270 NCBI chr10:101,795,652...101,810,409
Ensembl chr10:101,296,776...101,311,687
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:54,292,423...54,296,657
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:21,842,206...21,958,556
Ensembl chr12:16,728,524...16,764,097
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,407,880...3,484,130 JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO
IEA
(PMID:23632890)
GO_REF:0000107
RGD
Ensembl
PMID:23632890 GO_REF:0000107 NCBI chr19:54,654,101...54,740,586
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:164,808,722...164,819,865
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA
(PMID:23632890)
GO_REF:0000107
RGD
Ensembl
PMID:23632890 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,407,880...3,484,130 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      immune response 2236
        innate immune response 1025
          natural killer cell activation involved in immune response 30
            natural killer cell degranulation + 15
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to external stimulus 2804
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  natural killer cell activation involved in immune response 30
                    natural killer cell degranulation + 15
paths to the root