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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-beta T cell activation involved in immune response
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Accession:GO:0002287 term browser browse the term
Definition:The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: alpha-beta T cell activation during immune response;   alpha-beta T lymphocyte activation during immune response


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alpha-beta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2-M3 histocompatibility 2, M region locus 3 acts_upstream_of_or_within IMP (PMID:16476767) MGI PMID:16476767 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375 		JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in ISO
IDA
IBA 		(PMID:14605368) GO_Central
UniProt		 PMID:14605368 GO_REF:0000033 GO_REF:0000119 NCBI chr 9:118,307,259...118,315,176
Ensembl chr 9:118,307,280...118,315,200 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within IDA (PMID:17277142) MGI PMID:17277142 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IMP (PMID:24463518) UniProt PMID:24463518 NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001 		JBrowse link
G Il4ra interleukin 4 receptor, alpha acts_upstream_of_or_within IGI (PMID:16424184) MGI PMID:16424184 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Jak3 Janus kinase 3 involved_in IMP (PMID:16020505) BHF-UCL PMID:16020505 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IDA (PMID:9670042) BHF-UCL PMID:9670042 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IMP (PMID:24463518) UniProt PMID:24463518 NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Il2 interleukin 2 involved_in IGI (PMID:25642768) BHF-UCL PMID:25642768 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:18792410) MGI PMID:18792410 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO
IEA 		RGD
GO_Central
Ensembl		 PMID:24986443 GO_REF:0000096 GO_REF:0000107 RGD:329901907 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 involved_in IMP (PMID:25282160) UniProt PMID:25282160 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rc3h2 ring finger and CCCH-type zinc finger domains 2 involved_in IMP (PMID:25282160) UniProt PMID:25282160 NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915 		JBrowse link
G Smad7 SMAD family member 7 involved_in IMP (PMID:25642768) BHF-UCL PMID:25642768 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Tbx21 T-box 21 involved_in IDA (PMID:21151104) UniProt PMID:21151104 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IMP (PMID:23034280) MGI PMID:23034280 NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in IMP (PMID:25282160) UniProt PMID:25282160 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd69 CD69 antigen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:20696842) UniProt PMID:20696842 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665 		JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in IMP
ISO 		(PMID:28065600) UniProt
GO_Central		 PMID:28065600 GO_REF:0000119 NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in ISO (PMID:20696842) UniProt PMID:20696842 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Tbx21 T-box 21 involved_in IMP (PMID:21151104) UniProt PMID:21151104 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 involved_in IMP (PMID:24107315) UniProt PMID:24107315 NCBI chr 1:161,322,221...161,333,903
Ensembl chr 1:161,322,224...161,332,859 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IMP (PMID:24463518) UniProt PMID:24463518 NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IGI (PMID:12594267) MGI PMID:12594267 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IMP
IGI 		(PMID:16424184) MGI PMID:16424184 NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in TAS (PMID:11244049) UniProt PMID:11244049 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IDA (PMID:12242343) UniProt PMID:12242343 NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267 		JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within IMP (PMID:19783676) MGI PMID:19783676 NCBI chr18:24,122,134...24,138,428
Ensembl chr18:24,122,689...24,138,433 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 RING CCCH (C3H) domains 1 acts_upstream_of_or_within IMP (PMID:15917799) MGI PMID:15917799 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in IDA (PMID:15845453) BHF-UCL PMID:15845453 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in IC (PMID:14662900) BHF-UCL PMID:14662900 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in IC (PMID:15845453) BHF-UCL PMID:15845453 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IGI
IMP 		(PMID:16424184) MGI PMID:16424184 NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in TAS (PMID:11244049) UniProt PMID:11244049 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 acts_upstream_of_or_within IMP (PMID:11894097) MGI PMID:11894097 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IDA (PMID:12242343) UniProt PMID:12242343 NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in IDA (PMID:25282160) UniProt PMID:25282160 NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138 		JBrowse link
G Mir326 microRNA 326 acts_upstream_of_or_within IDA
IMP 		(PMID:19838199) MGI PMID:19838199 NCBI chr 7:99,201,476...99,201,570
Ensembl chr 7:99,201,476...99,201,570 		JBrowse link
G Nfkbid nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta involved_in IMP (PMID:25282160) UniProt PMID:25282160 NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171 		JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta involved_in IMP (PMID:25282160) UniProt PMID:25282160 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IMP (PMID:26098997) UniProt PMID:26098997 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISO
IDA 		(PMID:28262505) GO_Central
UniProt		 PMID:28262505 GO_REF:0000119 NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608 		JBrowse link
G Brd4 bromodomain containing 4 involved_in IMP (PMID:28262505) UniProt PMID:28262505 NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696 		JBrowse link
G Ep300 E1A binding protein p300 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 involved_in IBA
IDA 		(PMID:19501566) GO_Central
BHF-UCL		 PMID:19501566 GO_REF:0000033 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in IMP (PMID:36171294) UniProt PMID:36171294 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IMP (PMID:12829194) BHF-UCL PMID:12829194 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il4ra interleukin 4 receptor, alpha acts_upstream_of_or_within IGI (PMID:16424184) MGI PMID:16424184 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within IDA (PMID:12594267) MGI PMID:12594267 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IMP (PMID:26098997) UniProt PMID:26098997 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IMP (PMID:15987782) UniProt PMID:15987782 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818 		JBrowse link
G Rara retinoic acid receptor, alpha involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IDA (PMID:18354165) BHF-UCL PMID:18354165 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shb src homology 2 domain-containing transforming protein B acts_upstream_of_or_within IMP (PMID:24645804) MGI PMID:24645804 NCBI chr 4:45,423,278...45,530,804
Ensembl chr 4:45,423,278...45,532,470 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in IBA
ISO
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in IDA (PMID:19050256) UniProt PMID:19050256 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in IMP (PMID:19050256) UniProt PMID:19050256 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973 		JBrowse link
G Mir301 microRNA 301 acts_upstream_of_or_within IMP (PMID:22517757) MGI PMID:22517757 NCBI chr11:87,003,830...87,003,915
Ensembl chr11:87,003,830...87,003,915 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within IMP (PMID:18776904) MGI PMID:18776904 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta involved_in ISO (PMID:15322540) UniProt PMID:15322540 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IMP (PMID:18776904) MGI PMID:18776904 NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083 		JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IMP (PMID:24463518) UniProt PMID:24463518 NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001 		JBrowse link
G Foxp1 forkhead box P1 involved_in IDA (PMID:24859450) UniProt PMID:24859450 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in IMP (PMID:27147029) UniProt PMID:27147029 NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607 		JBrowse link
G Icos inducible T cell co-stimulator involved_in ISO (PMID:27135603) UniProt PMID:27135603 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479 		JBrowse link
G Icosl icos ligand involved_in ISO (PMID:24411167) UniProt PMID:24411167 NCBI chr10:77,904,921...77,915,359
Ensembl chr10:77,905,136...77,919,747 		JBrowse link
G Il21 interleukin 21 involved_in IMP (PMID:23045607) UniProt PMID:23045607 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il6 interleukin 6 involved_in IMP (PMID:23045607) UniProt PMID:23045607 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 acts_upstream_of_or_within IGI (PMID:23583643) MGI PMID:23583643 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rc3h2 ring finger and CCCH-type zinc finger domains 2 acts_upstream_of_or_within IGI (PMID:23583643) MGI PMID:23583643 NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cracr2a calcium release activated channel regulator 2A involved_in IMP
ISO 		(PMID:29987160) UniProt
GO_Central		 PMID:29987160 GO_REF:0000119 NCBI chr 6:127,538,299...127,651,197
Ensembl chr 6:127,538,301...127,651,211 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma acts_upstream_of_or_within TAS (PMID:12213961) MGI PMID:12213961 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of IGI
IMP 		(PMID:16424184) MGI PMID:16424184 NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Il18r1 interleukin 18 receptor 1 acts_upstream_of_or_within IMP (PMID:10227969) MGI PMID:10227969 NCBI chr 1:40,504,712...40,540,014
Ensembl chr 1:40,504,712...40,540,014 		JBrowse link
G Il4ra interleukin 4 receptor, alpha acts_upstream_of IGI (PMID:16424184) MGI PMID:16424184 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IDA (PMID:18579517) UniProt PMID:18579517 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005 		JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta involved_in IMP (PMID:31182790) MGI PMID:31182790 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B acts_upstream_of_or_within IMP (PMID:16081776) MGI PMID:16081776 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A involved_in IMP (PMID:15780988) UniProt PMID:15780988 NCBI chr 3:88,343,266...88,368,500
Ensembl chr 3:88,343,266...88,368,489 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Tmem98 transmembrane protein 98 involved_in IDA (PMID:25946230) UniProt PMID:25946230 NCBI chr11:80,701,192...80,712,859
Ensembl chr11:80,701,001...80,712,859 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 acts_upstream_of_or_within IGI (PMID:20706986) MGI PMID:20706986 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IMP (PMID:26410627) MGI PMID:26410627 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Spn sialophorin involved_in ISO
ISS 		GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within IGI (PMID:20706986) MGI PMID:20706986 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Tbx21 T-box 21 involved_in IDA (PMID:10761931) UniProt PMID:10761931 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like involved_in IMP (PMID:20421391), (PMID:21572431) UniProt PMID:20421391 PMID:21572431 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IMP (PMID:23241884) UniProt PMID:23241884 NCBI chr19:43,678,128...43,722,292
Ensembl chr19:43,678,111...43,722,136 		JBrowse link
G Mir873a microRNA 873a acts_upstream_of_or_within_positive_effect ISO (PMID:28837808) MGI PMID:28837808 NCBI chr 4:36,668,510...36,668,586
Ensembl chr 4:36,668,510...36,668,586 		JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta involved_in IMP (PMID:20383124) MGI PMID:20383124 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262 		JBrowse link
G Rora RAR-related orphan receptor alpha involved_in IMP (PMID:18164222) GO_Central PMID:18164222 NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528 		JBrowse link
G Rorc RAR-related orphan receptor gamma acts_upstream_of_or_within
involved_in 		IDA
IMP 		(PMID:18792410)
(PMID:16990136), (PMID:18164222)
(PMID:20383124) 		MGI
UniProt		 PMID:16990136 PMID:18164222 PMID:18792410 PMID:20383124 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like involved_in IMP (PMID:19578362), (PMID:22983707) UniProt PMID:19578362 PMID:22983707 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Il6 interleukin 6 involved_in IDA
IMP 		(PMID:27893700)
(PMID:16990136) 		UniProt PMID:16990136 PMID:27893700 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha involved_in IDA (PMID:27893700) UniProt PMID:27893700 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Irf4 interferon regulatory factor 4 involved_in IMP (PMID:22983707) UniProt PMID:22983707 NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959 		JBrowse link
G Ly9 lymphocyte antigen 9 involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:171,416,172...171,434,917
Ensembl chr 1:171,416,192...171,434,978 		JBrowse link
G Otud5 OTU domain containing 5 acts_upstream_of_or_within IMP (PMID:25470037) MGI PMID:25470037 NCBI chr  X:7,705,852...7,742,861
Ensembl chr  X:7,707,603...7,742,865 		JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:171,745,002...171,776,525
Ensembl chr 1:171,745,082...171,780,737 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in IMP (PMID:28065600) UniProt PMID:28065600 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in TAS (PMID:18368049) UniProt PMID:18368049 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like involved_in IMP (PMID:20421391), (PMID:21572431) UniProt PMID:20421391 PMID:21572431 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 acts_upstream_of_or_within IMP (PMID:16081776) MGI PMID:16081776 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of IGI (PMID:12594267) MGI PMID:12594267 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within
involved_in 		IDA
ISO 		(PMID:20706986) MGI
GO_Central		 PMID:20706986 GO_REF:0000119 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of IGI
IMP 		(PMID:16424184) MGI PMID:16424184 NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:20706986) MGI PMID:20706986 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha acts_upstream_of IGI (PMID:16424184) MGI PMID:16424184 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il6 interleukin 6 acts_upstream_of IDA (PMID:12594267) MGI PMID:12594267 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A involved_in IEA
ISO 		Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594 		JBrowse link
G Men1 multiple endocrine neoplasia 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Myb myeloblastosis oncogene involved_in ISO GO_Central GO_REF:0000119 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883 		JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, copper transporting, alpha polypeptide acts_upstream_of_or_within IMP (PMID:8434133) MGI PMID:8434133 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Il12b interleukin 12b involved_in ISS
ISO 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) involved_in IDA (PMID:19465928) UniProt PMID:19465928 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Rorc RAR-related orphan receptor gamma involved_in IMP (PMID:14691482) UniProt PMID:14691482 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    immune system process 3186
      leukocyte activation 1158
        lymphocyte activation 951
          T cell activation 685
            alpha-beta T cell activation 222
              alpha-beta T cell activation involved in immune response 93
                NK T cell activation involved in immune response + 0
                alpha-beta T cell differentiation involved in immune response + 92
                alpha-beta T cell proliferation involved in immune response + 0
Path 2
Term Annotations click to browse term
  biological_process 28626
    cellular process 18393
      cell activation 1318
        cell activation involved in immune response 360
          leukocyte activation involved in immune response 356
            lymphocyte activation involved in immune response 254
              T cell activation involved in immune response 154
                alpha-beta T cell activation involved in immune response 93
                  NK T cell activation involved in immune response + 0
                  alpha-beta T cell differentiation involved in immune response + 92
                  alpha-beta T cell proliferation involved in immune response + 0
paths to the root