Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:T cell activation involved in immune response
go back to main search page
Accession:GO:0002286 term browser browse the term
Definition:The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: T cell activation during immune response;   T lymphocyte activation during immune response


show annotations for term's descendants           Sort by:
T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1C CD1c molecule involved_in IDA (PMID:21167756) UniProt PMID:21167756 NCBI chr 1:158,289,923...158,294,774
Ensembl chr 1:158,289,923...158,294,774 		JBrowse link
G CD74 CD74 molecule involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G IFNA1 interferon alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:19130550) MGI
GO_Central		 PMID:19130550 GO_REF:0000033 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA10 interferon alpha 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,206,181...21,207,143
Ensembl chr 9:21,206,181...21,207,143 		JBrowse link
G IFNA13 interferon alpha 13 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,367,372...21,368,057
Ensembl chr 9:21,367,372...21,368,057 		JBrowse link
G IFNA14 interferon alpha 14 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005 		JBrowse link
G IFNA16 interferon alpha 16 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311 		JBrowse link
G IFNA17 interferon alpha 17 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222 		JBrowse link
G IFNA2 interferon alpha 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNA21 interferon alpha 21 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,165,637...21,166,660
Ensembl chr 9:21,165,637...21,166,660 		JBrowse link
G IFNA4 interferon alpha 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,186,618...21,187,587
Ensembl chr 9:21,186,618...21,187,587 		JBrowse link
G IFNA5 interferon alpha 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313 		JBrowse link
G IFNA6 interferon alpha 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,350,253...21,350,956 		JBrowse link
G IFNA7 interferon alpha 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,201,469...21,202,205
Ensembl chr 9:21,201,469...21,202,205 		JBrowse link
G IFNA8 interferon alpha 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185 		JBrowse link
G IFNB1 interferon beta 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNE interferon epsilon involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,480,839...21,482,313
Ensembl chr 9:21,480,839...21,482,313 		JBrowse link
G IFNK interferon kappa involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:27,524,290...27,526,498
Ensembl chr 9:27,524,290...27,526,498 		JBrowse link
G IFNW1 interferon omega 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:21,140,632...21,141,832
Ensembl chr 9:21,140,632...21,141,832 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 involved_in IDA (PMID:17294403) UniProt PMID:17294403 NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871 		JBrowse link
G MDK midkine involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G TRA T cell receptor alpha locus involved_in IDA (PMID:27036003) UniProt PMID:27036003 NCBI chr14:21,621,904...22,552,132 JBrowse link
G TRB T cell receptor beta locus involved_in IDA (PMID:27036003) UniProt PMID:27036003 NCBI chr 7:142,299,011...142,813,287 JBrowse link
alpha-beta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-G major histocompatibility complex, class I, G acts_upstream_of_or_within ISO (PMID:16476767) MGI PMID:16476767 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in IMP
IBA
IEA		 (PMID:17566017) UniProt
GO_Central
Ensembl		 PMID:17566017 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:17277142) MGI PMID:17277142 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB27A RAB27A, member RAS oncogene family acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:55,202,966...55,289,813
Ensembl chr15:55,202,966...55,319,113 		JBrowse link
G STX11 syntaxin 11 acts_upstream_of_or_within ISO (PMID:23042080), (PMID:23190531) MGI PMID:23042080 PMID:23190531 NCBI chr 6:144,139,963...144,191,939
Ensembl chr 6:144,150,487...144,191,939 		JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSC1 TSC complex subunit 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 involved_in IDA (PMID:18424730) UniProt PMID:18424730 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234 		JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in TAS (PMID:26683154) ARUK-UCL PMID:26683154 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IMP (PMID:32647003) UniProt PMID:32647003 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243 		JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGL2 fibrinogen like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848 		JBrowse link
G IFNL1 interferon lambda 1 involved_in IDA (PMID:19346497) UniProt PMID:19346497 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IDA (PMID:26492563) UniProt PMID:26492563 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G LGALS3 galectin 3 involved_in ISS (PMID:19706535) BHF-UCL PMID:19706535 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:18094328) UniProt PMID:18094328 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G JAK3 Janus kinase 3 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G FOXP3 forkhead box P3 involved_in IMP (PMID:23169781) UniProt PMID:23169781 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) MGI PMID:18792410 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G PF4 platelet factor 4 ISO RGD PMID:24986443 RGD:329901907 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD69 CD69 molecule involved_in IDA (PMID:24752896) UniProt PMID:24752896 NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901 		JBrowse link
G JAK3 Janus kinase 3 involved_in IDA (PMID:20696842) UniProt PMID:20696842 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G LGALS1 galectin 1 involved_in IDA (PMID:24752896) UniProt PMID:24752896 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802 		JBrowse link
G LOXL3 lysyl oxidase like 3 involved_in IEA
IDA
ISS		 (PMID:28065600) Ensembl
UniProt		 PMID:28065600 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IDA (PMID:20696842) UniProt PMID:20696842 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IDA (PMID:17008549) UniProt PMID:17008549 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
G ZNF271P zinc finger protein 271, pseudogene acts_upstream_of_or_within ISO (PMID:19783676) MGI PMID:19783676 NCBI chr18:35,290,272...35,310,766
Ensembl chr18:35,291,184...35,307,896
Ensembl chr18:35,291,184...35,307,896 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within		 ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IDA (PMID:20209097) UniProt PMID:20209097 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:20209097) UniProt PMID:20209097 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
positive regulation of gamma-delta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:21233315) UniProt PMID:21233315 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in IDA (PMID:12540904) UniProt PMID:12540904 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:27591323) UniProt PMID:27591323 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:27591323) UniProt PMID:27591323 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IL12B interleukin 12B involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL23R interleukin 23 receptor involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IDA
IEA		 (PMID:8766544) UniProt
Ensembl		 PMID:8766544 GO_REF:0000107 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802 		JBrowse link
G HLA-DMB major histocompatibility complex, class II, DM beta involved_in IMP (PMID:8139689) UniProt PMID:8139689 NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028 		JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IDA (PMID:17008549) UniProt PMID:17008549 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CD80 CD80 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477 		JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR326 microRNA 326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISS UniProt GO_REF:0000024 NCBI chr19:35,887,952...35,902,303
Ensembl chr19:35,887,630...35,902,303 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in IEA
IDA		 (PMID:28262505) Ensembl
UniProt		 PMID:28262505 GO_REF:0000107 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G EP300 E1A binding protein p300 involved_in IDA (PMID:28262505) UniProt PMID:28262505 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G IL12B interleukin 12B involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA
ISS		 Ensembl
GO_Central
BHF-UCL		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL23R interleukin 23 receptor involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in NAS (PMID:9915850) UniProt PMID:9915850 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G IL18 interleukin 18 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G PRKCZ protein kinase C zeta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IDA (PMID:18416830) BHF-UCL PMID:18416830 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR65 G protein-coupled receptor 65 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:88,005,135...88,014,811
Ensembl chr14:88,005,135...88,014,811 		JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227 		JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in IDA
IBA		 (PMID:12734330) UniProt
GO_Central		 PMID:12734330 GO_REF:0000033 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in NAS (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (PMID:19050256) UniProt PMID:19050256 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in NAS (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G MIR301A microRNA 301a acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:15322540) UniProt PMID:15322540 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:15322540) UniProt PMID:15322540 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in NAS (PMID:12374808) UniProt PMID:12374808 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523 		JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:26,438,341...26,567,803
Ensembl chr10:26,438,341...26,568,449 		JBrowse link
G FGL2 fibrinogen like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 involved_in IMP (PMID:2477710) BHF-UCL PMID:2477710 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ITGAL integrin subunit alpha L involved_in IMP (PMID:2477710) BHF-UCL PMID:2477710 NCBI chr16:30,472,742...30,523,185
Ensembl chr16:30,472,658...30,523,567 		JBrowse link
G PLXNA1 plexin A1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:126,983,115...127,037,389
Ensembl chr 3:126,982,693...127,037,389 		JBrowse link
G SEMA6D semaphorin 6D involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:47,184,089...47,774,228
Ensembl chr15:47,184,101...47,774,228 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC4D C-type lectin domain family 4 member D acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:156,147,373...156,177,744
Ensembl chr 1:156,147,366...156,177,752 		JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:20500684 RGD:4892204 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:18094328) UniProt PMID:18094328 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022 		JBrowse link
G RPS6 ribosomal protein S6 acts_upstream_of_or_within ISO (PMID:16357222) MGI PMID:16357222 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within		 ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISS
IEA
IBA		 UniProt
Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588 		JBrowse link
G FOXP1 forkhead box P1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:99,294,539...99,307,399
Ensembl chr13:99,294,539...99,307,399 		JBrowse link
G ICOS inducible T cell costimulator involved_in IDA (PMID:27135603) UniProt PMID:27135603 NCBI chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IDA (PMID:24411167) UniProt PMID:24411167 NCBI chr21:44,216,981...44,240,943
Ensembl chr21:44,215,382...44,241,446 		JBrowse link
G ICOSLG inducible T cell costimulator ligand involved_in IDA (PMID:24411167) UniProt PMID:24411167 NCBI chr21:5,022,531...5,046,683
Ensembl chr21:44,215,382...44,241,446 		JBrowse link
G IL21 interleukin 21 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL6 interleukin 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IDA (PMID:30523347) UniProt PMID:30523347 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:27135603) UniProt PMID:27135603 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACR2A calcium release activated channel regulator 2A involved_in IMP (PMID:29987160) UniProt PMID:29987160 NCBI chr12:3,615,328...3,753,109
Ensembl chr12:3,606,633...3,764,819 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IMP (PMID:15944249) UniProt PMID:15944249 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IL18R1 interleukin 18 receptor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192 		JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:156,147,373...156,177,744
Ensembl chr 1:156,147,366...156,177,752 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 involved_in IDA (PMID:14688310) UniProt PMID:14688310 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:32,928,153...32,944,315
Ensembl chr17:32,927,910...32,945,106 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) MGI PMID:20706986 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G SPN sialophorin involved_in IDA (PMID:18036228) UniProt PMID:18036228 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122 		JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:99,659,509...99,711,241
Ensembl chr10:99,659,509...99,711,241 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G RORC RAR related orphan receptor C involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:18792410) UniProt
MGI		 PMID:18792410 GO_REF:0000024 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G IL6 interleukin 6 involved_in ISS (PMID:27893700) UniProt PMID:27893700 GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA
ISS		 (PMID:27893700) Ensembl
UniProt		 PMID:27893700 GO_REF:0000107 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in ISS (PMID:27893700) UniProt PMID:27893700 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G JAK1 Janus kinase 1 involved_in TAS (PMID:27893700) UniProt PMID:27893700 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G LY9 lymphocyte antigen 9 involved_in IDA (PMID:22184727) UniProt PMID:22184727 NCBI chr 1:160,796,174...160,828,255
Ensembl chr 1:160,796,074...160,828,483 		JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (PMID:25470037) MGI PMID:25470037 NCBI chr  X:48,922,024...48,958,381
Ensembl chr  X:48,922,024...48,958,386 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IDA (PMID:22184727) UniProt PMID:22184727 NCBI chr 1:160,485,036...160,523,255
Ensembl chr 1:160,485,030...160,523,262 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 involved_in TAS (PMID:27893700) UniProt PMID:27893700 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993 		JBrowse link
G BCL3 BCL3 transcription coactivator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044 		JBrowse link
G BCL6 BCL6 transcription repressor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IDA
IEA		 (PMID:20484083) UniProt
Ensembl		 PMID:20484083 GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059 		JBrowse link
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) MGI PMID:20706986 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KMT2A lysine methyltransferase 2A involved_in IDA (PMID:20484083) UniProt PMID:20484083 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832 		JBrowse link
G MEN1 menin 1 involved_in IDA (PMID:20484083) UniProt PMID:20484083 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MYB MYB proto-oncogene, transcription factor involved_in IMP (PMID:20484083) UniProt PMID:20484083 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha involved_in
acts_upstream_of_or_within		 ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G IL12B interleukin 12B involved_in IDA (PMID:1673147) UniProt PMID:1673147 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754 		JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
T-helper cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZFPM1 zinc finger protein, FOG family member 1 involved_in IC (PMID:21646796) BHF-UCL PMID:21646796 NCBI chr16:88,451,769...88,537,031
Ensembl chr16:88,453,280...88,537,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27210
    immune system process 3306
      leukocyte activation 1157
        leukocyte activation involved in immune response 358
          lymphocyte activation involved in immune response 258
            T cell activation involved in immune response 155
              T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 14
              T cell differentiation involved in immune response + 107
              T cell proliferation involved in immune response + 6
              alpha-beta T cell activation involved in immune response + 100
              cytotoxic T cell degranulation + 5
              gamma-delta T cell activation involved in immune response + 1
Path 2
Term Annotations click to browse term
  biological_process 27210
    cellular process 19786
      cell activation 1391
        cell activation involved in immune response 362
          leukocyte activation involved in immune response 358
            lymphocyte activation involved in immune response 258
              T cell activation involved in immune response 155
                T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell + 14
                T cell differentiation involved in immune response + 107
                T cell proliferation involved in immune response + 6
                alpha-beta T cell activation involved in immune response + 100
                cytotoxic T cell degranulation + 5
                gamma-delta T cell activation involved in immune response + 1
paths to the root