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ONTOLOGY REPORT - ANNOTATIONS

Term:lymphocyte activation involved in immune response
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Accession:GO:0002285 term browser browse the term
Definition:A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: lymphocyte activation during immune response


show annotations for term's descendants           Sort by:
lymphocyte activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf4 interferon regulatory factor 4 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730 		JBrowse link
G Irf8 interferon regulatory factor 8 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062 		JBrowse link
G Irf9 interferon regulatory factor 9 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930 (PMID:23453632) RGD PMID:23453632 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
alpha-beta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdr2 cerebellar degeneration-related protein 2 acts_upstream_of_or_within ISO (PMID:29093272) RGD PMID:29093272 NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (PMID:16476767) RGD PMID:16476767 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
B cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr183 G protein-coupled receptor 183 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:108,115,064...108,116,010 		JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,640,546...108,641,115 JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,233,736...108,234,314
Ensembl chr 5:108,233,736...108,234,314 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO
IBA 		(PMID:12932356)
GO_REF:0000033 		RGD
GO_Central		 PMID:12932356 GO_REF:0000033 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,687,443...108,688,103
Ensembl chr 5:108,687,443...108,688,103 		JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511 		JBrowse link
G LOC120103158 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,494,288...108,494,937 JBrowse link
G LOC120103159 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,523,067...108,523,627 JBrowse link
B cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856663|MGI:2153718|MGI:96561 (PMID:11120811), (PMID:7671324), (PMID:8806812) 		Ensembl
RGD		 PMID:7671324 PMID:8806812 PMID:11120811 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Cd180 CD180 molecule involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:3581654 (PMID:10880523) 		GO_Central
RGD		 PMID:10880523 GO_REF:0000033 NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:35,589,451...35,603,982 		JBrowse link
G Cd19 CD19 molecule involved_in ISO
IEA 		(PMID:1373518), (PMID:16672701)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:1373518 PMID:16672701 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:190,417,853...190,424,355 		JBrowse link
G Gapt Grb2-binding adaptor protein, transmembrane involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:3809581 (PMID:18559951)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:18559951 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:43,660,900...43,665,485
Ensembl chr 2:43,660,900...43,665,448 		JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2679632 (PMID:14517301) 		Ensembl
RGD		 PMID:14517301 GO_REF:0000107 NCBI chr 9:3,529,117...3,713,712
Ensembl chr 9:3,529,841...3,713,712 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:10880523) 		Ensembl
RGD		 PMID:10880523 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin involved_in ISO
IEA
IBA 		(PMID:17566017)
(PMID:14605368)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:14605368 PMID:17566017 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:127,059,215...127,067,070
Ensembl chr 8:127,059,215...127,067,070 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:17277142) RGD PMID:17277142 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856656 (PMID:11266473) 		Ensembl
RGD		 PMID:11266473 GO_REF:0000107 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080), (PMID:23190531) RGD PMID:23042080 PMID:23190531 NCBI chr 1:9,111,216...9,140,227
Ensembl chr 1:9,107,796...9,178,455 		JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P17433 (PMID:31000603) 		Ensembl
RGD		 PMID:31000603 GO_REF:0000107 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062 		JBrowse link
G Muc19 mucin 19, oligomeric acts_upstream_of_or_within ISO (PMID:37475871) RGD PMID:37475871 NCBI chr 7:124,897,424...125,018,582
Ensembl chr 7:124,897,424...125,018,582 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO MGI:2386100 (PMID:12928432) RGD PMID:12928432 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P23611 (PMID:31000603) 		Ensembl
RGD		 PMID:31000603 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540 		JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964) 		Ensembl
RGD		 PMID:14607964 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Cdh17 cadherin 17 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15688343) 		Ensembl
RGD		 PMID:15688343 GO_REF:0000107 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23045607) 		UniProt
RGD		 PMID:23045607 GO_REF:0000024 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23045607) 		UniProt
RGD		 PMID:23045607 GO_REF:0000024 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irf8 interferon regulatory factor 8 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P17433 (PMID:31000603) 		Ensembl
RGD		 PMID:31000603 GO_REF:0000107 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within ISO MGI:4235940 (PMID:23997217) RGD PMID:23997217 NCBI chr 4:163,371,125...163,384,676
Ensembl chr 4:163,338,702...163,384,367 		JBrowse link
G Phf14 PHD finger protein 14 involved_in IEA
ISO 		GO_REF:0000107
(PMID:33035772) 		Ensembl
RGD		 PMID:33035772 GO_REF:0000107 NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,975,439...41,162,043 		JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23045607) 		Ensembl
RGD		 PMID:23045607 GO_REF:0000107 NCBI chr 8:60,418,173...60,445,176
Ensembl chr 8:60,436,844...60,445,176 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:P23611 (PMID:31000603) 		Ensembl
RGD		 PMID:31000603 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase acts_upstream_of_or_within
involved_in 		ISO (PMID:17713479)
(PMID:21518874) 		RGD PMID:17713479 PMID:21518874 NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:157,444,697...157,456,356 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:20421391), (PMID:21572431)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20421391 PMID:21572431 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052 		JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISO 		GO_REF:0000107
(PMID:7529792) 		Ensembl
RGD		 PMID:7529792 GO_REF:0000107 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO MGI:2183944 (PMID:15280420) RGD PMID:15280420 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2653925 (PMID:14716311) 		Ensembl
RGD		 PMID:14716311 GO_REF:0000107 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861 		JBrowse link
G Exosc3 exosome component 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr 5:64,369,495...64,374,711
Ensembl chr 5:64,369,495...64,374,902 		JBrowse link
G Exosc6 exosome component 6 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr19:55,931,523...55,932,937
Ensembl chr19:55,931,523...55,932,937 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (PMID:17713479) RGD PMID:17713479 NCBI chr16:86,220,345...86,228,930
Ensembl chr16:86,220,279...86,229,926 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857946 (PMID:12743174) 		Ensembl
RGD		 PMID:12743174 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857940|MGI:2151801 (PMID:10430621), (PMID:12743174) 		Ensembl
RGD		 PMID:10430621 PMID:12743174 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:109352|MGI:3653701 (PMID:16618598), (PMID:17015724) 		Ensembl
RGD		 PMID:16618598 PMID:17015724 GO_REF:0000107 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844 		JBrowse link
G Nbn nibrin involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:15668383)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:15668383 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930|MGI:5501251 (PMID:25124037), (PMID:31182790) RGD PMID:25124037 PMID:31182790 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19139091)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19139091 GO_REF:0000024 GO_REF:0000107 NCBI chr11:81,818,914...81,862,623
Ensembl chr11:81,819,285...81,862,395 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20080757) 		UniProt
RGD		 PMID:20080757 GO_REF:0000024 NCBI chr11:81,991,352...82,013,306
Ensembl chr11:81,991,360...82,013,306 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO 		GO_REF:0000024
(PMID:20080757) 		UniProt
RGD		 PMID:20080757 GO_REF:0000024 NCBI chr20:7,683,890...7,708,437 JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:33831416)
GO_REF:0000033
GO_REF:0000107 		UniProt
RGD
GO_Central
Ensembl		 PMID:33831416 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:101,717,619...101,787,092
Ensembl chr14:101,716,868...101,782,480 		JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:9642267) 		Ensembl
RGD		 PMID:9642267 GO_REF:0000107 NCBI chr 1:173,702,338...173,763,540
Ensembl chr 1:173,702,347...173,763,947 		JBrowse link
G Ung uracil-DNA glycosylase acts_upstream_of_or_within ISO MGI:1343961 (PMID:17015724) RGD PMID:17015724 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO MGI:1926771|MGI:3047571|MGI:3641440 (PMID:17713479) RGD PMID:17713479 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27174992) 		Ensembl
RGD		 PMID:27174992 GO_REF:0000107 NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059 		JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:1861796 (PMID:9009202) RGD PMID:9009202 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368 		JBrowse link
G Cdh17 cadherin 17 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15688343) 		Ensembl
RGD		 PMID:15688343 GO_REF:0000107 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:15146182), (PMID:19217325) 		UniProt
RGD		 PMID:15146182 PMID:19217325 GO_REF:0000024 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276 		JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (PMID:25729399) RGD PMID:25729399 NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973 		JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25729399) 		Ensembl
RGD		 PMID:25729399 GO_REF:0000107 NCBI chr  X:119,997,523...120,180,643
Ensembl chr  X:119,997,552...120,180,634 		JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19217325)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19217325 GO_REF:0000024 GO_REF:0000107 NCBI chr12:19,144,474...19,152,951
Ensembl chr12:19,124,662...19,152,918 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in IEA
ISO 		GO_REF:0000107
(PMID:19217325) 		Ensembl
RGD		 PMID:19217325 GO_REF:0000107 NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129 		JBrowse link
G Notch2 notch receptor 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19217325)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19217325 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO 		GO_REF:0000024
(PMID:10881171) 		UniProt
RGD		 PMID:10881171 GO_REF:0000024 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C10h17orf99 similar to human chromosome 17 open reading frame 99 involved_in IEA
ISO 		GO_REF:0000107
(PMID:28978694) 		Ensembl
RGD		 PMID:28978694 GO_REF:0000107 NCBI chr10:103,514,067...103,526,132
Ensembl chr10:103,515,201...103,525,878 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISO (PMID:19597478) RGD PMID:19597478 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977 		JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:108,357,399...108,365,253 		JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10755614) 		Ensembl
RGD		 PMID:10755614 GO_REF:0000107 NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242 		JBrowse link
memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333 		JBrowse link
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2656240 (PMID:25271321) 		Ensembl
RGD		 PMID:25271321 GO_REF:0000107 NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:32,367,670...32,416,568 		JBrowse link
natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11714776)
(PMID:15905190) 		RGD PMID:11714776 PMID:15905190 NCBI chr13:86,583,727...86,606,902
Ensembl chr13:86,584,826...86,616,009 		JBrowse link
G Cd244l1 CD244 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:86,547,250...86,569,026
Ensembl chr13:86,551,430...86,569,026 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:19130550) 		GO_Central
RGD		 PMID:19130550 GO_REF:0000033 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:108,115,064...108,116,010 		JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,640,546...108,641,115 JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,233,736...108,234,314
Ensembl chr 5:108,233,736...108,234,314 		JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,687,443...108,688,103
Ensembl chr 5:108,687,443...108,688,103 		JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511 		JBrowse link
G Il12b interleukin 12B IMP RGD PMID:14960310 RGD:1600048 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G LOC120103158 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,494,288...108,494,937 JBrowse link
G LOC120103159 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,523,067...108,523,627 JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO
IEA 		(PMID:24760828)
GO_REF:0000107 		RGD
Ensembl		 PMID:24760828 GO_REF:0000107 NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102 		JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:25786175), (PMID:28652325) RGD PMID:25786175 PMID:28652325 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651 		JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 acts_upstream_of_or_within ISO (PMID:31024568) RGD PMID:31024568 NCBI chr15:46,117,211...46,145,258
Ensembl chr15:46,117,874...46,145,266 		JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (PMID:32839608), (PMID:33911019) RGD PMID:32839608 PMID:33911019 NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856656 (PMID:11266473) 		Ensembl
RGD		 PMID:11266473 GO_REF:0000107 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262 		JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (PMID:23042080), (PMID:23190531) RGD PMID:23042080 PMID:23190531 NCBI chr 1:9,111,216...9,140,227
Ensembl chr 1:9,107,796...9,178,455 		JBrowse link
G Unc13d unc-13 homolog D acts_upstream_of_or_within ISO MGI:3628822 (PMID:17420270) RGD PMID:17420270 NCBI chr10:101,795,652...101,810,409
Ensembl chr10:101,795,652...101,810,409 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:54,292,423...54,296,657
Ensembl chr10:54,292,806...54,296,654 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:21,842,206...21,958,556
Ensembl chr12:21,842,228...21,958,552 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS 		(PMID:18424730)
GO_REF:0000024 		RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26000965) 		Ensembl
RGD		 PMID:26000965 GO_REF:0000107 NCBI chr 8:115,989,721...115,995,822
Ensembl chr 8:115,987,176...115,995,472 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103034|MGI:2158438 (PMID:10490661) 		Ensembl
RGD		 PMID:10490661 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3696705 (PMID:16275384) 		Ensembl
RGD		 PMID:16275384 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3695433 (PMID:17137798) 		Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471 		JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3582343 (PMID:29341118) 		Ensembl
RGD		 PMID:29341118 GO_REF:0000107 NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:92,926,184...92,927,830 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,407,880...3,484,130 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 acts_upstream_of_or_within ISO MGI:2670590 (PMID:20709292) RGD PMID:20709292 NCBI chr 1:87,659,863...87,665,048
Ensembl chr 1:87,651,271...87,665,048 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5297105 (PMID:20709292) 		Ensembl
RGD		 PMID:20709292 GO_REF:0000107 NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:12,069,414...12,078,369 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:180,174,931...180,186,007
Ensembl chr 2:179,201,527...179,219,994
Ensembl chr 2:179,201,527...179,219,994 		JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (PMID:20709292) RGD PMID:20709292 NCBI chr 2:178,500,238...178,669,328
Ensembl chr 2:178,517,412...178,582,680 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:31,383,925...31,413,872 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:19706535) RGD PMID:19706535 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24463518) 		Ensembl
RGD		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16020505) 		BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9670042) 		Ensembl
RGD		 PMID:9670042 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24463518) 		Ensembl
RGD		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO
IEA 		(PMID:23169781)
GO_REF:0000107 		RGD
Ensembl		 PMID:23169781 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (PMID:25642768) RGD PMID:25642768 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) RGD PMID:18792410 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25282160)
GO_REF:0000117 		Ensembl
RGD
UniProt		 PMID:25282160 GO_REF:0000107 GO_REF:0000117 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA
ISO 		GO_REF:0000117
(PMID:25282160) 		UniProt
RGD		 PMID:25282160 GO_REF:0000117 NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:41,531,617...41,589,715 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25642768) 		Ensembl
RGD		 PMID:25642768 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21151104) 		Ensembl
RGD		 PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3530739 (PMID:23034280) 		Ensembl
RGD		 PMID:23034280 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:177,095,185...177,109,031 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:25282160)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:25282160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd69 Cd69 molecule involved_in ISO (PMID:24752896) RGD PMID:24752896 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:20696842) RGD PMID:20696842 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Lgals1 galectin 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:24752896)
GO_REF:0000107 		RGD
Ensembl		 PMID:24752896 GO_REF:0000107 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800 		JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO
IEA 		(PMID:28065600)
GO_REF:0000117 		RGD
UniProt		 PMID:28065600 GO_REF:0000117 NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in ISO
IEA 		(PMID:20696842)
GO_REF:0000107 		RGD
Ensembl		 PMID:20696842 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21151104) 		Ensembl
RGD		 PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (PMID:24107315) RGD PMID:24107315 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:76,366,771...76,376,608 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:17008549)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24463518) 		Ensembl
RGD		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:96559 (PMID:12594267) 		Ensembl
RGD		 PMID:12594267 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:105367|MGI:2182089 (PMID:16424184) 		Ensembl
RGD		 PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr18:15,543,604...15,559,084
Ensembl chr18:15,543,516...15,559,837 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3581675 (PMID:15917799) 		Ensembl
RGD		 PMID:15917799 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816 		JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 acts_upstream_of_or_within ISO (PMID:32022930) RGD PMID:32022930 NCBI chr 8:123,326,233...123,353,148
Ensembl chr 8:123,325,975...123,353,148 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:2385534 (PMID:29259245) RGD PMID:29259245 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044 		JBrowse link
G Itm2a integral membrane protein 2A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5645968 (PMID:24831988) 		Ensembl
RGD		 PMID:24831988 GO_REF:0000107 NCBI chr  X:76,559,183...76,565,144
Ensembl chr  X:76,559,181...76,565,437 		JBrowse link
G Lgals1 galectin 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21753146) 		Ensembl
RGD		 PMID:21753146 GO_REF:0000107 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800 		JBrowse link
G Lgals8 galectin 8 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21753146) 		Ensembl
RGD		 PMID:21753146 GO_REF:0000107 NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:5501251 (PMID:25124037) RGD PMID:25124037 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2448069 (PMID:10926756) 		Ensembl
RGD		 PMID:10926756 GO_REF:0000107 NCBI chr 1:252,427,356...252,430,309
Ensembl chr 1:252,427,162...252,430,742 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:35995859) RGD PMID:35995859 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12496423) 		Ensembl
RGD		 PMID:12496423 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr 5:64,369,495...64,374,711
Ensembl chr 5:64,369,495...64,374,902 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr19:55,931,523...55,932,937
Ensembl chr19:55,931,523...55,932,937 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:31806351)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:31806351 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:121,950,129...121,972,937
Ensembl chr 4:121,950,840...121,972,891 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28114273)
GO_REF:0000117
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28114273 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:210,429,672...210,479,042
Ensembl chr 1:210,430,127...210,479,035 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28114273)
GO_REF:0000117
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28114273 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:78,128,325...78,135,931 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:163,846,687...163,859,851 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) RGD PMID:20671152 NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23306439), (PMID:23333305), (PMID:23333306) 		Ensembl
RGD		 PMID:23306439 PMID:23333305 PMID:23333306 GO_REF:0000107 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA 		(PMID:29656893)
GO_REF:0000033 		RGD
GO_Central		 PMID:29656893 GO_REF:0000033 NCBI chr 3:140,391,611...140,462,273
Ensembl chr 3:140,389,220...140,462,609 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,554,921...9,646,186
Ensembl chr16:9,553,854...9,588,510 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:37,031,045...37,035,859
Ensembl chr 2:37,031,045...37,032,328 		JBrowse link
G Tfrc transferrin receptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:26642240) 		UniProt
Ensembl
RGD		 PMID:26642240 GO_REF:0000024 GO_REF:0000107 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO
IEA 		(PMID:23345425), (PMID:23760478)
(PMID:15077110), (PMID:15159415)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23241889) 		Ensembl
RGD		 PMID:23241889 GO_REF:0000107 NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q9JK91 (PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:14988498) 		AgBase
Ensembl
RGD		 PMID:14988498 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000117
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:14988498 GO_REF:0000033 GO_REF:0000117 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (PMID:12023368) RGD PMID:12023368 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4127920 (PMID:25404367) 		Ensembl
RGD		 PMID:25404367 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:7688139) RGD PMID:7688139 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:1830926) RGD PMID:1830926 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) RGD PMID:12882831 PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 1:191,053,228...191,055,554 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q9JK91 (PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9015183) RGD PMID:9015183 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2180194 (PMID:12882831) 		Ensembl
RGD		 PMID:12882831 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:14688363) 		Ensembl
RGD		 PMID:14688363 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:29230018)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:29230018 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA 		(PMID:27591323)
GO_REF:0000107 		RGD
Ensembl		 PMID:27591323 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18713990) 		Ensembl
RGD		 PMID:18713990 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO
IEA 		(PMID:23632890)
GO_REF:0000107 		RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr19:54,654,101...54,740,586
Ensembl chr19:54,620,807...54,740,586 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:187,033,140...187,064,587 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:164,808,722...164,819,865
Ensembl chr 4:164,808,722...164,819,865 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA 		(PMID:23632890)
GO_REF:0000107 		RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,407,880...3,484,130 JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:30842412) 		Ensembl
RGD		 PMID:30842412 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:138,315,282...138,335,766 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO
IEA 		UniProtKB:P60568 (PMID:22962438)
GO_REF:0000107 		RGD
Ensembl		 PMID:22962438 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO
IEA 		UniProtKB:P22301 (PMID:22962438)
GO_REF:0000107 		RGD
Ensembl		 PMID:22962438 GO_REF:0000107 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
ISS 		(PMID:11460154)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO 		GO_REF:0000024
(PMID:8766544)
(PMID:11046035) 		UniProt
RGD		 PMID:8766544 PMID:11046035 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
G RT1-DMb RT1 class II, locus DMb involved_in ISO
IEA 		(PMID:8139689)
GO_REF:0000107 		RGD
Ensembl		 PMID:8139689 GO_REF:0000107 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17008549) 		UniProt
Ensembl
RGD		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) RGD PMID:15845453 NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:105367|MGI:2182089 (PMID:16424184) 		Ensembl
RGD		 PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2446070 (PMID:11894097) 		Ensembl
RGD		 PMID:11894097 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in IEA
ISO 		GO_REF:0000107
(PMID:25282160) 		Ensembl
RGD		 PMID:25282160 GO_REF:0000107 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:61,212,317...61,266,272 		JBrowse link
G Mir326 microRNA 326 acts_upstream_of_or_within ISO (PMID:19838199) RGD PMID:19838199 NCBI chr 1:163,266,165...163,266,259
Ensembl chr 1:163,266,165...163,266,259 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26098997) 		Ensembl
RGD		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28262505)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28262505 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IBA
ISO
IEA 		GO_REF:0000033
(PMID:19501566)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:19501566 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:36171294)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:36171294 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12829194) 		Ensembl
RGD		 PMID:12829194 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) RGD PMID:12594267 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26098997) 		Ensembl
RGD		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO 		GO_REF:0000024
(PMID:15987782) 		UniProt
RGD		 PMID:15987782 GO_REF:0000024 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO
IEA 		(PMID:18416830)
GO_REF:0000107 		RGD
Ensembl		 PMID:18416830 GO_REF:0000107 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18354165) 		Ensembl
RGD		 PMID:18354165 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:35668320) RGD PMID:35668320 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:123,219,633...123,266,285 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3721903 (PMID:24645804) 		Ensembl
RGD		 PMID:24645804 GO_REF:0000107 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4128102 (PMID:21211721) 		Ensembl
RGD		 PMID:21211721 GO_REF:0000107 NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961 		JBrowse link
G Mir181b1 microRNA 181b-1 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr13:52,037,228...52,037,337
Ensembl chr13:52,037,228...52,037,337 		JBrowse link
G Mir181b2 microRNA 181b-2 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr 3:43,026,666...43,026,753
Ensembl chr 3:43,026,666...43,026,753 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA
ISO 		GO_REF:0000107
(PMID:21518874) 		Ensembl
RGD		 PMID:21518874 GO_REF:0000107 NCBI chr10:63,601,990...63,638,851
Ensembl chr10:63,601,993...63,638,851 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3696705 (PMID:16275384) 		Ensembl
RGD		 PMID:16275384 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3525439 (PMID:11057672) 		Ensembl
RGD		 PMID:11057672 GO_REF:0000107 NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3695433 (PMID:17137798) 		Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:25310967)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:25310967 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:34,698,955...34,719,819 		JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2158436 (PMID:15240675) 		Ensembl
RGD		 PMID:15240675 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp683 zinc finger protein 683 involved_in ISO (PMID:22885984) RGD PMID:22885984 NCBI chr 5:151,558,880...151,569,937
Ensembl chr 5:151,561,480...151,569,764 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in ISO
IEA
IBA 		(PMID:12734330)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12734330 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:190,603,522...190,609,258 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (PMID:19050256) RGD PMID:19050256 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in ISO (PMID:19050256) RGD PMID:19050256 NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059 		JBrowse link
G Mir301a microRNA 301a acts_upstream_of_or_within ISO (PMID:22517757) RGD PMID:22517757 NCBI chr10:72,422,599...72,422,698
Ensembl chr10:72,422,599...72,422,698 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 NAS RGD PMID:10651948 RGD:1331512 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA 		(PMID:15322540)
GO_REF:0000107 		RGD
Ensembl		 PMID:15322540 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:15322540) RGD PMID:15322540 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:177,095,185...177,109,031 		JBrowse link
T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:24310610) RGD PMID:24310610 NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:125,810,060...125,895,574 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19845798)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19845798 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954 		JBrowse link
G Ifna1 interferon, alpha 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:19130550) 		GO_Central
RGD		 PMID:19130550 GO_REF:0000033 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,115,064...108,116,010
Ensembl chr 5:108,115,064...108,116,010 		JBrowse link
G Ifna4l1 interferon, alpha 4 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,640,546...108,641,115 JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,233,736...108,234,314
Ensembl chr 5:108,233,736...108,234,314 		JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,687,443...108,688,103
Ensembl chr 5:108,687,443...108,688,103 		JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 involved_in ISO
IEA 		(PMID:17294403)
GO_REF:0000107 		RGD
Ensembl		 PMID:17294403 GO_REF:0000107 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G LOC120103158 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,494,288...108,494,937 JBrowse link
G LOC120103159 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:108,523,067...108,523,627 JBrowse link
G Mdk midkine involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28183532)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28183532 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:109284 (PMID:17698590) 		Ensembl
RGD		 PMID:17698590 GO_REF:0000107 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:17698590) RGD PMID:17698590 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116 		JBrowse link
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein acts_upstream_of_or_within ISO (PMID:17403904) RGD PMID:17403904 NCBI chr17:89,849,474...89,941,099
Ensembl chr17:89,671,716...89,941,089 		JBrowse link
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3582343 (PMID:29341118) 		Ensembl
RGD		 PMID:29341118 GO_REF:0000107 NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:2477710) RGD PMID:2477710 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Itgal integrin subunit alpha L involved_in ISO
IEA 		(PMID:2477710)
GO_REF:0000107 		RGD
Ensembl		 PMID:2477710 GO_REF:0000107 NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225 		JBrowse link
G Plxna1 plexin A1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16715077) 		Ensembl
RGD		 PMID:16715077 GO_REF:0000107 NCBI chr 4:123,295,165...123,340,132
Ensembl chr 4:123,297,244...123,340,428 		JBrowse link
G Sema6d semaphorin 6D involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000107
(PMID:16715077) 		Ensembl
RGD		 PMID:16715077 GO_REF:0000107 NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:16715077) RGD PMID:16715077 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISS
ISO 		GO_REF:0000024
(PMID:16715077) 		UniProt
RGD		 PMID:16715077 GO_REF:0000024 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4d C-type lectin domain family 4, member D acts_upstream_of_or_within ISO (PMID:23602766) RGD PMID:23602766 NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:158,275,341...158,287,055 		JBrowse link
G Clec4e C-type lectin domain family 4, member E acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5013826 (PMID:23602766) 		Ensembl
RGD		 PMID:23602766 GO_REF:0000107 NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:158,293,311...158,298,467 		JBrowse link
G Fcer1g Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:2384004 (PMID:23602766) 		GO_Central
RGD		 PMID:23602766 GO_REF:0000033 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859 		JBrowse link
G Sema4a semaphorin 4A involved_in IEA
ISO 		GO_REF:0000107
(PMID:15780988) 		Ensembl
RGD		 PMID:15780988 GO_REF:0000107 NCBI chr 2:176,194,248...176,215,752
Ensembl chr 2:176,194,255...176,212,258 		JBrowse link
T cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule IEP RGD PMID:20500684 RGD:4892204 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Rps6 ribosomal protein S6 acts_upstream_of_or_within ISO MGI:2387471|MGI:98834 (PMID:16357222) RGD PMID:16357222 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857755 (PMID:9176118) 		Ensembl
RGD		 PMID:9176118 GO_REF:0000107 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:83,406,427...83,417,238 		JBrowse link
G Slfn2 schlafen family member 2 involved_in ISO (PMID:20190759) RGD PMID:20190759 NCBI chr10:68,450,861...68,457,198
Ensembl chr10:68,455,363...68,457,329 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in IBA
ISO
IEA 		GO_REF:0000033
(PMID:14608036)
GO_REF:0000002 		GO_Central
RGD
InterPro		 PMID:14608036 GO_REF:0000002 GO_REF:0000033 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:76,366,771...76,376,608 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24463518) 		Ensembl
RGD		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:24859450) RGD PMID:24859450 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO 		GO_REF:0000024
(PMID:27147029) 		UniProt
RGD		 PMID:27147029 GO_REF:0000024 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977 		JBrowse link
G Icos inducible T-cell co-stimulator involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:27135603)
GO_REF:0000107 		RGD
Ensembl		 PMID:27135603 GO_REF:0000107 NCBI chr 9:69,862,042...69,900,864
Ensembl chr 9:69,877,785...69,900,960 		JBrowse link
G Icoslg inducible T-cell co-stimulator ligand involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:24411167)
GO_REF:0000107 		RGD
Ensembl		 PMID:24411167 GO_REF:0000107 NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,078...10,610,365 		JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23045607) 		UniProt
RGD		 PMID:23045607 GO_REF:0000024 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23045607) 		UniProt
RGD		 PMID:23045607 GO_REF:0000024 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:30523347) RGD PMID:30523347 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in 		IEA
ISO 		GO_REF:0000107
MGI:2442789 (PMID:23583643)
GO_REF:0000117 		Ensembl
RGD
UniProt		 PMID:23583643 GO_REF:0000107 GO_REF:0000117 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
MGI:2685397 (PMID:23583643) 		UniProt
RGD		 PMID:23583643 GO_REF:0000117 NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:41,531,617...41,589,715 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA 		(PMID:27135603)
GO_REF:0000107 		RGD
Ensembl		 PMID:27135603 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357 		JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cracr2a calcium release activated channel regulator 2A involved_in ISO (PMID:29987160) RGD PMID:29987160 NCBI chr 4:162,094,247...162,207,926
Ensembl chr 4:162,110,929...162,221,529 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15944249) RGD PMID:15944249 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Il12a interleukin 12A acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G Il18r1 interleukin 18 receptor 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2136765 (PMID:10227969) 		Ensembl
RGD		 PMID:10227969 GO_REF:0000107 NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18579517) 		Ensembl
RGD		 PMID:18579517 GO_REF:0000107 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930 (PMID:31182790) RGD PMID:31182790 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2179545 (PMID:16081776) 		Ensembl
RGD		 PMID:16081776 GO_REF:0000107 NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420 		JBrowse link
G Sema4a semaphorin 4A involved_in IEA
ISO 		GO_REF:0000107
(PMID:15780988) 		Ensembl
RGD		 PMID:15780988 GO_REF:0000107 NCBI chr 2:176,194,248...176,215,752
Ensembl chr 2:176,194,255...176,212,258 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 involved_in ISO (PMID:14688310) RGD PMID:14688310 NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Tmem98 transmembrane protein 98 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:25946230)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:25946230 GO_REF:0000024 GO_REF:0000107 NCBI chr10:66,293,895...66,304,806
Ensembl chr10:66,293,867...66,304,803 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 acts_upstream_of_or_within ISO MGI:103034 (PMID:20706986) RGD PMID:20706986 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:26410627) 		Ensembl
RGD		 PMID:26410627 GO_REF:0000107 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Spn sialophorin involved_in ISO
ISS 		(PMID:18036228)
GO_REF:0000024 		RGD
UniProt		 PMID:18036228 GO_REF:0000024 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:191,178,096...191,187,852 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:96556 (PMID:20706986) RGD PMID:20706986 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10761931) 		Ensembl
RGD		 PMID:10761931 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:20421391), (PMID:21572431)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20421391 PMID:21572431 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052 		JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23241884) 		Ensembl
RGD		 PMID:23241884 GO_REF:0000107 NCBI chr 1:252,508,594...252,550,269
Ensembl chr 1:252,508,594...252,550,269 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930 (PMID:20383124) RGD PMID:20383124 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:18164222) RGD PMID:18164222 NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730 		JBrowse link
G Rorc RAR-related orphan receptor C involved_in
acts_upstream_of_or_within 		ISO (PMID:31776512)
(PMID:16990136), (PMID:18164222)
(PMID:18792410)
MGI:2386114 (PMID:20383124) 		RGD PMID:16990136 PMID:18164222 PMID:18792410 PMID:20383124 PMID:31776512 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19578362), (PMID:22983707)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19578362 PMID:22983707 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16990136), (PMID:27893700)
(PMID:27893700) 		UniProt
RGD		 PMID:16990136 PMID:27893700 GO_REF:0000024 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISS
ISO 		GO_REF:0000024
(PMID:27893700) 		UniProt
RGD		 PMID:27893700 GO_REF:0000024 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Irf4 interferon regulatory factor 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22983707) 		Ensembl
RGD		 PMID:22983707 GO_REF:0000107 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730 		JBrowse link
G Ly9 lymphocyte antigen 9 involved_in ISO
IEA 		(PMID:22184727)
GO_REF:0000107 		RGD
Ensembl		 PMID:22184727 GO_REF:0000107 NCBI chr13:86,610,762...86,633,314
Ensembl chr13:86,611,784...86,657,293 		JBrowse link
G Otud5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO MGI:2386448|MGI:5752247 (PMID:25470037) RGD PMID:25470037 NCBI chr  X:17,296,750...17,331,257
Ensembl chr  X:17,298,029...17,331,054 		JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:22184727) RGD PMID:22184727 NCBI chr13:86,916,956...86,937,697
Ensembl chr13:86,916,122...86,938,354 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28065600)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28065600 GO_REF:0000024 GO_REF:0000107 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:20421391), (PMID:21572431)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20421391 PMID:21572431 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:111,084,717...111,107,052
Ensembl chr 6:111,084,717...111,107,052 		JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:2158443 (PMID:16081776) RGD PMID:16081776 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:20484083)
(PMID:20706986)
GO_REF:0000107 		RGD
Ensembl		 PMID:20484083 PMID:20706986 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) RGD PMID:20706986 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO
IEA 		(PMID:20484083)
GO_REF:0000107 		RGD
Ensembl		 PMID:20484083 GO_REF:0000107 NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317 		JBrowse link
G Men1 menin 1 involved_in ISO
IEA 		(PMID:20484083)
GO_REF:0000107 		RGD
Ensembl		 PMID:20484083 GO_REF:0000107 NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:213,068,166...213,074,120 		JBrowse link
G Myb MYB proto-oncogene, transcription factor involved_in ISO
IEA 		(PMID:20484083)
GO_REF:0000107 		RGD
Ensembl		 PMID:20484083 GO_REF:0000107 NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:17,759,309...17,792,547 		JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (PMID:8434133) RGD PMID:8434133 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:1673147)
GO_REF:0000107 		RGD
Ensembl		 PMID:1673147 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:30150402) 		UniProt
RGD		 PMID:30150402 GO_REF:0000024 NCBI chr19:392,858...400,529
Ensembl chr19:392,183...400,902 		JBrowse link
G Ptger4 prostaglandin E receptor 4 involved_in ISS
ISO 		GO_REF:0000024
(PMID:19465928) 		UniProt
RGD		 PMID:19465928 GO_REF:0000024 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Rorc RAR-related orphan receptor C involved_in ISO (PMID:14691482) RGD PMID:14691482 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      leukocyte activation 1068
        leukocyte activation involved in immune response 336
          lymphocyte activation involved in immune response 238
            B cell activation involved in immune response + 107
            T cell activation involved in immune response + 137
            natural killer cell activation involved in immune response + 27
            natural killer cell differentiation involved in immune response + 5
            natural killer cell proliferation involved in immune response + 0
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cell activation 1226
        cell activation involved in immune response 340
          leukocyte activation involved in immune response 336
            lymphocyte activation involved in immune response 238
              B cell activation involved in immune response + 107
              T cell activation involved in immune response + 137
              natural killer cell activation involved in immune response + 27
              natural killer cell differentiation involved in immune response + 5
              natural killer cell proliferation involved in immune response + 0
paths to the root