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ONTOLOGY REPORT - ANNOTATIONS

Term:activation of innate immune response
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Accession:GO:0002218 term browser browse the term
Definition:Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
Synonyms:alt_id: GO:0002219


show annotations for term's descendants           Sort by:
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO
IEA
IBA		 (PMID:19158675), (PMID:19158676), (PMID:19158679)
GO_REF:0000107
GO_REF:0000002
(PMID:19158676)
GO_REF:0000033		 RGD
Ensembl
InterPro
GO_Central		 PMID:19158675 PMID:19158676 PMID:19158679 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr13:88,397,516...88,439,325
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS		 (PMID:32298652)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32298652 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA
IBA		 (PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208)
GO_REF:0000107
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:29426904), (PMID:32911480), (PMID:32911481), (PMID:32913000)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G ENSRNOG00000069878 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Ensembl chr13:85,977,035...85,994,718 JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24739961) RGD PMID:24739961 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp2 guanylate binding protein 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:24739961)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24739961 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp4 guanylate binding protein 4 involved_in ISO
IEA		 (PMID:24739961)
GO_REF:0000107		 RGD
Ensembl		 PMID:24739961 GO_REF:0000107 NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:231,305,244...231,318,879 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:24739961)
GO_REF:0000107		 RGD
Ensembl		 PMID:24739961 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gbp7 guanylate binding protein 7 involved_in ISO
IEA		 (PMID:24739961)
GO_REF:0000107		 RGD
Ensembl		 PMID:24739961 GO_REF:0000107 NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:231,275,640...231,297,278 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:24971542) RGD PMID:24971542 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
IEA
ISS		 (PMID:20628368)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ifi214 interferon activated gene 214 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:88,472,400...88,483,335
Ensembl chr13:85,940,078...85,951,004 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:45,264,404...45,290,737
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G LOC102556096 pyrin domain-containing protein 3-like involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:88,444,247...88,461,817
Ensembl chr13:85,912,044...85,929,007 		JBrowse link
G Matr3 matrin 3 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr18:27,428,190...27,474,421
Ensembl chr18:27,163,714...27,193,166 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:20628368)		 UniProt
RGD		 PMID:20628368 GO_REF:0000024 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:88,550,224...88,567,892
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16648852)		 UniProt
Ensembl
RGD		 PMID:16648852 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:26,743,658...26,771,783
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 involved_in ISO (PMID:22672233) RGD PMID:22672233 NCBI chr 1:172,357,648...172,365,205
Ensembl chr 1:162,922,806...162,930,363 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:56,277,134...56,332,229
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:56,336,957...56,412,796
Ensembl chr10:55,843,001...55,912,774 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO
IEA		 (PMID:28712728)
GO_REF:0000107		 RGD
Ensembl		 PMID:28712728 GO_REF:0000107 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISO
IEA
ISS		 (PMID:26046437)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26046437 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:17,275,445...17,280,018
Ensembl chr  X:14,603,539...14,608,087 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Pspc1 paraspeckle component 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr15:34,941,445...35,027,460
Ensembl chr15:30,828,626...30,911,202 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA
IBA		 (PMID:19158675)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19158675 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO
IEA		 (PMID:28712728)
GO_REF:0000107		 RGD
Ensembl		 PMID:28712728 GO_REF:0000107 NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO
IEA		 (PMID:28712728)
GO_REF:0000107		 RGD
Ensembl		 PMID:28712728 GO_REF:0000107 NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO
IEA		 (PMID:22783022)
GO_REF:0000107		 RGD
Ensembl		 PMID:22783022 GO_REF:0000107 NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IBA
ISO
IEA		 GO_REF:0000033
(PMID:23910378)
GO_REF:0000002
GO_REF:0000107
(PMID:21947006), (PMID:23258412), (PMID:23910378)		 GO_Central
RGD
InterPro
Ensembl		 PMID:21947006 PMID:23258412 PMID:23910378 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:25636800)
GO_REF:0000107
GO_REF:0000033
MGI:3046789 (PMID:15661922)		 RGD
Ensembl
GO_Central		 PMID:15661922 PMID:25636800 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 MGI:1860885 (PMID:15661922)
GO_REF:0000107		 RGD
Ensembl		 PMID:15661922 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA		 (PMID:25686612)
GO_REF:0000107		 RGD
Ensembl		 PMID:25686612 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20628368)		 Ensembl
UniProt
RGD		 PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:56,847,837...56,886,302
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Trim5 tripartite motif-containing 5 involved_in ISO (PMID:21512573) RGD PMID:21512573 NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:158,720,410...158,814,012 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO
IEA		 (PMID:28712728)
GO_REF:0000107		 RGD
Ensembl		 PMID:28712728 GO_REF:0000107 NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32200799), (PMID:32296175), (PMID:32350114), (PMID:33109609)		 UniProt
RGD		 PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609 GO_REF:0000024 NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IEA
IBA		 (PMID:30135424), (PMID:30193849)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033		 RGD
Ensembl
InterPro
GO_Central		 PMID:30135424 PMID:30193849 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:161,332,760...161,335,591
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in ISO
IEA		 (PMID:31685995)
GO_REF:0000107		 RGD
Ensembl		 PMID:31685995 GO_REF:0000107 NCBI chr 3:176,183,111...176,210,812
Ensembl chr 3:155,764,980...155,821,242 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) RGD PMID:15294986 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12719478)
GO_REF:0000107
(PMID:19358895)		 RGD
Ensembl		 PMID:12719478 PMID:19358895 GO_REF:0000107 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Fcna ficolin A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:28,844,036...28,847,441
Ensembl chr 3:8,445,907...8,449,105 		JBrowse link
G Fcnb ficolin B involved_in ISO
IEA		 (PMID:21037097)
GO_REF:0000107		 RGD
Ensembl		 PMID:21037097 GO_REF:0000107 NCBI chr 3:31,791,750...31,800,188
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO
IEA
ISS		 (PMID:21037097)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21037097 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,199,277...95,202,599
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (PMID:15294986)
GO_REF:0000107		 RGD
Ensembl		 PMID:15294986 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) RGD PMID:22966085 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19358895)
GO_REF:0000107		 RGD
Ensembl		 PMID:19358895 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (PMID:12719478) RGD PMID:12719478 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA		 (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)
GO_REF:0000107
(PMID:39322678)		 RGD
Ensembl		 PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Ddx41 DEAD-box helicase 41 involved_in ISO (PMID:35613581) RGD PMID:35613581 NCBI chr17:9,108,030...9,113,562
Ensembl chr17:9,103,010...9,108,415 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:37832545)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37832545 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpk1 alpha-kinase 1 involved_in ISO
IBA		 (PMID:28222186), (PMID:28877472), (PMID:30111836)
(PMID:30111836)
GO_REF:0000033		 RGD
GO_Central		 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 NCBI chr 2:218,801,425...218,924,013
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Becn1 beclin 1 involved_in ISO
IEA		 (PMID:34796041)
GO_REF:0000107		 RGD
Ensembl		 PMID:34796041 GO_REF:0000107 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA		 (PMID:23258413)
GO_REF:0000107		 RGD
Ensembl		 PMID:23258413 GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:23478265) RGD PMID:23478265 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA
IBA		 (PMID:19211564)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19211564 GO_REF:0000033 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Ipo5 importin 5 involved_in ISO (PMID:31340999) RGD PMID:31340999 NCBI chr15:104,397,626...104,447,985
Ensembl chr15:98,005,299...98,041,126 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO
IEA		 (PMID:8524823)
GO_REF:0000107		 RGD
Ensembl		 PMID:8524823 GO_REF:0000107 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO
IEA		 (PMID:21931555)
GO_REF:0000107		 RGD
Ensembl		 PMID:21931555 GO_REF:0000107 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16125763), (PMID:20451243) RGD PMID:16125763 PMID:20451243 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO
IEA
IBA		 (PMID:19576794)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19576794 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:23910378), (PMID:35388221)
GO_REF:0000107		 RGD
Ensembl		 PMID:23910378 PMID:35388221 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:29441066)
GO_REF:0000107		 RGD
Ensembl		 PMID:29441066 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISO
IBA
ISS		 (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:218,927,724...218,942,111
Ensembl chr 2:216,234,774...216,267,841 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 involved_in ISO
IEA
IBA		 (PMID:31390091)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:31390091 GO_REF:0000033 GO_REF:0000107 NCBI chr13:107,223,499...107,248,358
Ensembl chr13:104,694,805...104,719,673 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:20501938), (PMID:23015697) RGD PMID:20501938 PMID:23015697 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO
IEA		 (PMID:17392790)
GO_REF:0000107		 RGD
Ensembl		 PMID:17392790 GO_REF:0000107 NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:22607805) RGD PMID:22607805 NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Washc4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) RGD PMID:33749590 NCBI chr 7:22,075,546...22,127,847
Ensembl chr 7:20,187,922...20,240,226 		JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elp6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) RGD PMID:30097576 NCBI chr 8:119,158,380...119,173,483
Ensembl chr 8:110,279,979...110,295,067 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 IMP RGD PMID:19226379 RGD:2312509 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO
IEA
IBA		 (PMID:17600090), (PMID:19211564), (PMID:33727702)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:17600090 PMID:19211564 PMID:33727702 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) RGD PMID:19265123 NCBI chr 8:119,969,908...120,071,270
Ensembl chr 8:111,091,503...111,193,255 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000002
GO_REF:0000107
MGI:1346060|MGI:2385681 (PMID:12719478), (PMID:12872135), (PMID:14764662)		 InterPro
Ensembl
RGD		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Reg3g regenerating family member 3 gamma involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17635956)		 UniProt
Ensembl
RGD		 PMID:17635956 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:110,924,168...110,926,723 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:108005 (PMID:12719478) RGD PMID:12719478 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:20037584), (PMID:38670073)
UniProtKB:Q9EPW9 (PMID:20037584)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:20037584 PMID:38670073 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 (PMID:20037584)
GO_REF:0000107
UniProtKB:Q9QUK6 (PMID:20037584)		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA		 UniProtKB:P22366 (PMID:18820679)
GO_REF:0000107		 RGD
Ensembl		 PMID:18820679 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:22011580) RGD PMID:22011580 NCBI chr10:39,537,759...39,585,038
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) RGD PMID:19265123 NCBI chr 8:119,969,908...120,071,270
Ensembl chr 8:111,091,503...111,193,255 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:96,197,019...96,237,357
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim11 tripartite motif-containing 11 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27498865)		 UniProt
Ensembl
RGD		 PMID:27498865 GO_REF:0000024 GO_REF:0000107 NCBI chr10:44,255,019...44,270,711
Ensembl chr10:43,758,354...43,771,138 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO
ISS		 (PMID:39322678)
GO_REF:0000024		 RGD
UniProt		 PMID:39322678 GO_REF:0000024 NCBI chr 9:22,981,880...22,993,536
Ensembl chr 9:15,297,531...15,496,090 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12172553), (PMID:26440888)		 Ensembl
RGD		 PMID:12172553 PMID:26440888 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aurkb aurora kinase B involved_in IEA
ISO		 GO_REF:0000107
(PMID:33542149)		 Ensembl
RGD		 PMID:33542149 GO_REF:0000107 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 involved_in ISO
IEA		 (PMID:32792394)
GO_REF:0000107		 RGD
Ensembl		 PMID:32792394 GO_REF:0000107 NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:202,671,305...202,674,188 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA		 (PMID:32911482), (PMID:32912999)
GO_REF:0000107		 RGD
Ensembl		 PMID:32911482 PMID:32912999 GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:32715615) RGD PMID:32715615 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lyplal1 lysophospholipase-like 1 involved_in ISO (PMID:37802025) RGD PMID:37802025 NCBI chr13:100,158,060...100,189,339
Ensembl chr13:97,626,451...97,657,867 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO
IEA		 (PMID:35460603)
GO_REF:0000107		 RGD
Ensembl		 PMID:35460603 GO_REF:0000107 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) RGD PMID:35322803 NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Ppp6c protein phosphatase 6, catalytic subunit involved_in ISO
IEA		 (PMID:32474700)
GO_REF:0000107		 RGD
Ensembl		 PMID:32474700 GO_REF:0000107 NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:22,931,577...22,962,113 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) RGD PMID:33273464 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:37890481)		 UniProt
Ensembl
RGD		 PMID:37890481 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,679,004...37,701,979
Ensembl chr20:37,132,592...37,155,567 		JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in ISO (PMID:38418882) RGD PMID:38418882 NCBI chr10:14,411,692...14,417,357
Ensembl chr10:13,907,253...13,912,841 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO
IEA		 (PMID:33476576)
GO_REF:0000107		 RGD
Ensembl		 PMID:33476576 GO_REF:0000107 NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:35438208)		 Ensembl
RGD		 PMID:35438208 GO_REF:0000107 NCBI chr 5:151,105,303...151,143,843
Ensembl chr 5:145,831,446...145,859,993 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itch itchy E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:27736772)
GO_REF:0000107		 RGD
Ensembl		 PMID:27736772 GO_REF:0000107 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:31881323)		 Ensembl
RGD		 PMID:31881323 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:33674311) RGD PMID:33674311 NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283 		JBrowse link
G Sec14l1 SEC14-like lipid binding 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23843640)		 Ensembl
RGD		 PMID:23843640 GO_REF:0000107 NCBI chr10:102,818,693...102,865,841
Ensembl chr10:102,319,920...102,367,068 		JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
IEA		 (PMID:30927622)
GO_REF:0000107		 RGD
Ensembl		 PMID:30927622 GO_REF:0000107 NCBI chr 7:135,527,710...135,532,826
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO
IEA		 (PMID:27736772)
GO_REF:0000107		 RGD
Ensembl		 PMID:27736772 GO_REF:0000107 NCBI chr 4:83,152,549...83,208,463
Ensembl chr 4:81,821,989...81,879,100 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO
IEA		 (PMID:22908223)
GO_REF:0000107		 RGD
Ensembl		 PMID:22908223 GO_REF:0000107 NCBI chr  X:101,385,686...101,395,371
Ensembl chr  X:97,092,388...97,099,309 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS		 (PMID:19164550)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA		 (PMID:21187438)
GO_REF:0000107		 RGD
Ensembl		 PMID:21187438 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO
IEA		 (PMID:25865883)
GO_REF:0000107		 RGD
Ensembl		 PMID:25865883 GO_REF:0000107 NCBI chr18:3,602,535...3,628,108
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISS
ISO		 GO_REF:0000024
(PMID:17600090)		 UniProt
RGD		 PMID:17600090 GO_REF:0000024 NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:22043923) RGD PMID:22043923 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(PMID:22043923)		 UniProt
RGD		 PMID:22043923 GO_REF:0000024 NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,867,503...63,890,872
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO
IEA		 (PMID:38092000)
GO_REF:0000107		 RGD
Ensembl		 PMID:38092000 GO_REF:0000107 NCBI chr 7:9,775,016...9,781,447
Ensembl chr 7:9,124,332...9,130,762 		JBrowse link
G Abhd8 abhydrolase domain containing 8 involved_in IEA
ISO		 GO_REF:0000107
(PMID:39225180)		 Ensembl
RGD		 PMID:39225180 GO_REF:0000107 NCBI chr16:18,178,441...18,185,178
Ensembl chr16:18,144,464...18,157,667 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS		 (PMID:29164996)
GO_REF:0000024		 RGD
UniProt		 PMID:29164996 GO_REF:0000024 NCBI chr 5:171,757,181...171,761,271
Ensembl chr 5:166,474,966...166,479,017 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:34615873)		 UniProt
RGD		 PMID:34615873 GO_REF:0000024 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO
IEA		 (PMID:26037928)
GO_REF:0000107		 RGD
Ensembl		 PMID:26037928 GO_REF:0000107 NCBI chr 8:122,794,870...122,843,265
Ensembl chr 8:113,913,373...113,965,066 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:30612879)		 UniProt
Ensembl
RGD		 PMID:30612879 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO		 GO_REF:0000024
(PMID:26347139)		 UniProt
RGD		 PMID:26347139 GO_REF:0000024 NCBI chr10:12,288,514...12,303,337
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO
IEA		 (PMID:25277106)
GO_REF:0000107		 RGD
Ensembl		 PMID:25277106 GO_REF:0000107 NCBI chr10:12,055,809...12,093,449
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO
IEA		 (PMID:32514138)
GO_REF:0000107
(PMID:29887864)		 RGD
Ensembl		 PMID:29887864 PMID:32514138 GO_REF:0000107 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO
IEA		 (PMID:27929086)
GO_REF:0000107		 RGD
Ensembl		 PMID:27929086 GO_REF:0000107 NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim65 tripartite motif-containing 65 involved_in IEA
ISO		 GO_REF:0000107
(PMID:34512673)		 Ensembl
RGD		 PMID:34512673 GO_REF:0000107 NCBI chr10:101,847,822...101,863,052
Ensembl chr10:101,357,937...101,364,971 		JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISS
ISO		 GO_REF:0000024
(PMID:36586411)		 UniProt
RGD		 PMID:36586411 GO_REF:0000024 NCBI chr 3:33,761,338...33,764,207
Ensembl chr 3:13,363,504...13,366,474 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:37962578)		 UniProt
Ensembl
RGD		 PMID:37962578 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:18342009)
GO_REF:0000107		 RGD
Ensembl		 PMID:18342009 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO
IEA		 (PMID:16203728)
GO_REF:0000107		 RGD
Ensembl		 PMID:16203728 GO_REF:0000107 NCBI chr 2:36,660,399...36,762,584
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:18342009)
GO_REF:0000107		 RGD
Ensembl		 PMID:18342009 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) RGD PMID:28656966 NCBI chr 9:1,440,444...1,441,632
Ensembl chr 9:1,353,306...1,354,584 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS		 (PMID:19164550)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA
IBA		 (PMID:18411269), (PMID:21187438)
GO_REF:0000107
(PMID:17475874)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:17475874 PMID:18411269 PMID:21187438 GO_REF:0000033 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Gpatch3 G patch domain containing 3 involved_in ISO
IEA
IBA		 (PMID:28414768)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
InterPro
Ensembl
GO_Central		 PMID:28414768 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:151,083,970...151,093,382
Ensembl chr 5:145,800,111...145,809,250 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO
IEA		 MGI:5141085 (PMID:21703540)
GO_REF:0000107		 RGD
Ensembl		 PMID:21703540 GO_REF:0000107 NCBI chr 8:53,486,866...53,503,498
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO
IEA
ISS		 (PMID:26471729)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr10:106,152,756...106,208,306
Ensembl chr10:105,654,812...105,709,913 		JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO
IEA		 (PMID:17460044), (PMID:26471729)
GO_REF:0000107		 RGD
Ensembl		 PMID:17460044 PMID:26471729 GO_REF:0000107 NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,253,852...12,275,983 		JBrowse link
G Sec14l1 SEC14-like lipid binding 1 involved_in ISO
IEA
IBA		 (PMID:23843640)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23843640 GO_REF:0000033 GO_REF:0000107 NCBI chr10:102,818,693...102,865,841
Ensembl chr10:102,319,920...102,367,068 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO
IEA
ISS		 (PMID:26471729)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr11:95,665,971...95,689,423
Ensembl chr11:82,161,619...82,185,087 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:86,286,531...86,295,803
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20385881)		 UniProt
Ensembl
RGD		 PMID:20385881 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA		 (PMID:26599367)
GO_REF:0000107		 RGD
Ensembl		 PMID:26599367 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107		 RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) RGD PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:19865078)
GO_REF:0000107		 RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:15474016)
GO_REF:0000107		 RGD
Ensembl		 PMID:15474016 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21695056)		 Ensembl
RGD		 PMID:21695056 GO_REF:0000107 NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:86,286,531...86,295,803
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IBA
IEA		 (PMID:21900486)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:21900486 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:163,133,151...163,166,420
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19948740)		 UniProt
Ensembl
RGD		 PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20385881)		 UniProt
Ensembl
RGD		 PMID:20385881 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA		 (PMID:28609714)
GO_REF:0000107		 RGD
Ensembl		 PMID:28609714 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:171,931,495...171,931,589
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:159,209,965...159,210,033 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:160,011,158...160,011,245
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA		 (PMID:18511497)
GO_REF:0000107		 RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO
IEA		 (PMID:17395780)
GO_REF:0000107		 RGD
Ensembl		 PMID:17395780 GO_REF:0000107 NCBI chr13:45,673,396...45,699,798
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
IEA		 (PMID:31281713)
GO_REF:0000107		 RGD
Ensembl		 PMID:31281713 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO
IEA		 (PMID:28898289)
GO_REF:0000107		 RGD
Ensembl		 PMID:28898289 GO_REF:0000107 NCBI chr 4:83,152,549...83,208,463
Ensembl chr 4:81,821,989...81,879,100 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460), (PMID:31134514) RGD PMID:29407460 PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:19912257)
GO_REF:0000107		 RGD
Ensembl		 PMID:19912257 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir210 microRNA 210 involved_in ISO (PMID:38742642) RGD PMID:38742642 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IBA
ISO		 GO_REF:0000033
(PMID:25917084)		 GO_Central
RGD		 PMID:25917084 GO_REF:0000033 NCBI chr 7:119,030,225...119,103,875
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
IEA		 (PMID:14716310)
GO_REF:0000107		 RGD
Ensembl		 PMID:14716310 GO_REF:0000107 NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO (PMID:26231120) RGD PMID:26231120 NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,245,410...1,306,947 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO
IEA		 (PMID:19587007)
GO_REF:0000107		 RGD
Ensembl		 PMID:19587007 GO_REF:0000107 NCBI chr13:45,673,396...45,699,798
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:16378096) RGD PMID:16378096 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO
IEA		 (PMID:20829348)
GO_REF:0000107		 RGD
Ensembl		 PMID:20829348 GO_REF:0000107 NCBI chr 7:9,042,125...9,047,807
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:30332431)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:30332431 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:2,207,716...2,218,738
Ensembl chr 9:2,120,744...2,132,572 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:55,136,043...55,139,106
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO
IEA		 (PMID:12150927)
GO_REF:0000107		 RGD
Ensembl		 PMID:12150927 GO_REF:0000107 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO
IEA		 MGI:2387941 (PMID:16236719)
GO_REF:0000107		 RGD
Ensembl		 PMID:16236719 GO_REF:0000107 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23589304)		 UniProt
Ensembl
RGD		 PMID:23589304 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO
IBA
IEA
ISS		 (PMID:27426725)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:27426725 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:110,311,384...110,317,757
Ensembl chr 7:108,430,792...108,437,111 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:31376096 RGD:329337378 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO
IEA
IBA
ISS		 (PMID:20829348)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:20829348 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within ISO
IEA		 MGI:5085850 (PMID:22763455)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763455 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA		 (PMID:29395066)
GO_REF:0000033		 RGD
GO_Central		 PMID:29395066 GO_REF:0000033 NCBI chr19:45,141,043...45,184,136
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20584979)		 Ensembl
RGD		 PMID:20584979 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) RGD PMID:20728433 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand acts_upstream_of_or_within ISO (PMID:23907535) RGD PMID:23907535 NCBI chr13:64,710,129...64,713,837 JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO
IEA		 (PMID:35343654)
GO_REF:0000107		 RGD
Ensembl		 PMID:35343654 GO_REF:0000107 NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:184,262,371...184,329,823 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in ISO
IEA		 (PMID:26095358)
GO_REF:0000107		 RGD
Ensembl		 PMID:26095358 GO_REF:0000107 NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:Q00993|UniProtKB:Q60805 (PMID:18083102)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18083102 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:35343654) RGD PMID:35343654 NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:22665479), (PMID:27662089), (PMID:31484767), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856) RGD PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr10:56,277,134...56,332,229
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Gkn2 gastrokine 2 acts_upstream_of_or_within ISO
IEA		 (PMID:32226647)
GO_REF:0000107		 RGD
Ensembl		 PMID:32226647 GO_REF:0000107 NCBI chr 4:121,335,642...121,381,680
Ensembl chr 4:119,818,280...119,824,363 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO
IEA		 MGI:2180015 (PMID:28928055)
GO_REF:0000107		 RGD
Ensembl		 PMID:28928055 GO_REF:0000107 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190)
MGI:5465108 (PMID:22753929)		 UniProt
Ensembl
RGD		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... GO_REF:0000024 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:27432880)
GO_REF:0000107		 RGD
Ensembl		 PMID:27432880 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:32424362), (PMID:34678144)
GO_REF:0000107
(PMID:30674671), (PMID:31932628), (PMID:34678144)		 UniProt
RGD
Ensembl		 PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf34 ring finger protein 34 involved_in ISO
IEA
ISS		 (PMID:25012219)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:25012219 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,364,461...39,385,391
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO
IEA		 (PMID:11058605), (PMID:12791997), (PMID:12796777)
GO_REF:0000107
(PMID:27007849)		 RGD
Ensembl		 PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 GO_REF:0000107 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:29452636), (PMID:30279485)
GO_REF:0000107
MGI:2660793 (PMID:11894098)		 RGD
Ensembl		 PMID:11894098 PMID:29452636 PMID:30279485 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO
IEA		 (PMID:29452636)
GO_REF:0000107		 RGD
Ensembl		 PMID:29452636 GO_REF:0000107 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator involved_in ISO
IEA		 (PMID:28436939)
GO_REF:0000107		 RGD
Ensembl		 PMID:28436939 GO_REF:0000107 NCBI chr13:50,218,149...50,238,430
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO
IEA		 (PMID:22412986)
GO_REF:0000107		 RGD
Ensembl		 PMID:22412986 GO_REF:0000107 NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:25891078) RGD PMID:25891078 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:31875558) RGD PMID:31875558 NCBI chr15:58,799,477...58,816,840
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755)
GO_REF:0000107
(PMID:15692052), (PMID:27007849)
(PMID:23892723)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)		 RGD
Ensembl		 PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More... GO_REF:0000107 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO
IEA		 (PMID:23806334)
GO_REF:0000107		 RGD
Ensembl		 PMID:23806334 GO_REF:0000107 NCBI chr 2:80,021,381...80,046,898
Ensembl chr 2:78,290,959...78,316,422 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO
IEA		 (PMID:12527755)
GO_REF:0000107		 RGD
Ensembl		 PMID:12527755 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)
GO_REF:0000107
(PMID:17947236)
MGI:2660793 (PMID:11894098)		 RGD
Ensembl		 PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More... GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19667203), (PMID:22607974), (PMID:29452636)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19667203 PMID:22607974 PMID:29452636 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO
IEA		 (PMID:23258413)
GO_REF:0000107		 RGD
Ensembl		 PMID:23258413 GO_REF:0000107 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Clec4e C-type lectin domain family 4, member E involved_in ISO
ISS		 (PMID:24101491)
GO_REF:0000024		 RGD
UniProt		 PMID:24101491 GO_REF:0000024 NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Inava innate immunity activator involved_in ISO
IEA		 (PMID:28436939)
GO_REF:0000107		 RGD
Ensembl		 PMID:28436939 GO_REF:0000107 NCBI chr13:50,218,149...50,238,430
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945), (PMID:31875558) RGD PMID:28593945 PMID:31875558 NCBI chr15:58,799,477...58,816,840
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO
IEA		 (PMID:31649195)
GO_REF:0000107		 RGD
Ensembl		 PMID:31649195 GO_REF:0000107 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO
IEA		 (PMID:31649195)
GO_REF:0000107		 RGD
Ensembl		 PMID:31649195 GO_REF:0000107 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Rnf144a ring finger protein 144A involved_in ISO
IEA		 (PMID:37955227)
GO_REF:0000107		 RGD
Ensembl		 PMID:37955227 GO_REF:0000107 NCBI chr 6:48,628,241...48,748,241
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:23910378)
GO_REF:0000107		 RGD
Ensembl		 PMID:23910378 GO_REF:0000107 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:30,708,714...30,733,104
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp2 guanylate binding protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25774715), (PMID:25774716)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:25774715), (PMID:25774716)
GO_REF:0000107		 RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in ISO
IEA		 (PMID:25704810)
GO_REF:0000107		 RGD
Ensembl		 PMID:25704810 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) RGD PMID:37832545 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37916870)		 Ensembl
RGD		 PMID:37916870 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:39255680) RGD PMID:39255680 NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO
IEA		 (PMID:36745868)
GO_REF:0000107		 RGD
Ensembl		 PMID:36745868 GO_REF:0000107 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 involved_in ISO
IEA		 (PMID:37832545)
GO_REF:0000107		 RGD
Ensembl		 PMID:37832545 GO_REF:0000107 NCBI chr 7:113,556,157...113,587,351
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 involved_in ISO
IEA		 (PMID:37802025)
GO_REF:0000107		 RGD
Ensembl		 PMID:37802025 GO_REF:0000107 NCBI chr  X:132,230,243...132,266,139
Ensembl chr  X:127,352,345...127,388,245 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO
IEA		 (PMID:22328336)
GO_REF:0000107		 RGD
Ensembl		 PMID:22328336 GO_REF:0000107 NCBI chr14:18,007,342...18,145,980
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:33,087,940...33,208,843
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA		 (PMID:20080593)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080593 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc134 coiled-coil domain containing 134 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:38670073)		 UniProt
Ensembl
RGD		 PMID:38670073 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:115,526,537...115,539,155
Ensembl chr 7:113,644,639...113,659,050 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23246432)
(PMID:28943315)		 UniProt
RGD		 PMID:23246432 PMID:28943315 GO_REF:0000024 NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO
IEA		 (PMID:34554188)
GO_REF:0000107		 RGD
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:26173909) RGD PMID:26173909 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO		 GO_REF:0000024
(PMID:23812099)		 UniProt
RGD		 PMID:23812099 GO_REF:0000024 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,316,806...18,357,863
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO
IEA		 (PMID:31511697)
GO_REF:0000107		 RGD
Ensembl		 PMID:31511697 GO_REF:0000107 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO
IEA		 (PMID:23871209)
GO_REF:0000107		 RGD
Ensembl		 PMID:23871209 GO_REF:0000107 NCBI chr10:56,206,680...56,223,189
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:22461501)
GO_REF:0000107		 RGD
Ensembl		 PMID:22461501 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:93,652,888...93,661,419
Ensembl chr 1:84,525,590...84,534,677 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G LOC134486712 platelet glycoprotein 4-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,372,301...18,408,431 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28943315)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28943315 GO_REF:0000024 GO_REF:0000107 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37575012)		 Ensembl
RGD		 PMID:37575012 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO
IEA		 (PMID:28656979)
GO_REF:0000107		 RGD
Ensembl		 PMID:28656979 GO_REF:0000107 NCBI chr 1:88,203,352...88,239,858
Ensembl chr 1:79,068,904...79,108,556 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325) RGD PMID:23582325 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:33718825)		 UniProt
Ensembl
RGD		 PMID:33718825 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:31189953), (PMID:36442502), (PMID:39173637)
(PMID:26642356), (PMID:26814970)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:52,573,730...52,700,869
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29958799)		 UniProt
RGD		 PMID:29958799 GO_REF:0000024 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) RGD PMID:32514138 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:28465465)		 UniProt
RGD		 PMID:28465465 GO_REF:0000024 NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28716882)		 UniProt
Ensembl
RGD		 PMID:28716882 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:27043286) RGD PMID:27043286 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) RGD PMID:31836654 NCBI chr 4:64,894,663...64,904,495 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23812099)		 UniProt
Ensembl
RGD		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 (PMID:23812099)
GO_REF:0000107		 RGD
Ensembl		 PMID:23812099 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO
IEA		 (PMID:28094437)
GO_REF:0000107		 RGD
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr 3:134,465,469...134,488,859
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO (PMID:39173637) RGD PMID:39173637 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616 		JBrowse link
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO
IEA		 (PMID:38092000)
GO_REF:0000107		 RGD
Ensembl		 PMID:38092000 GO_REF:0000107 NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19570976), (PMID:21277849)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19570976 PMID:21277849 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Slc46a2 solute carrier family 46, member 2 involved_in ISO
IEA		 (PMID:28539433)
GO_REF:0000107		 RGD
Ensembl		 PMID:28539433 GO_REF:0000107 NCBI chr 5:79,594,003...79,603,074
Ensembl chr 5:74,800,226...74,808,128 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:36002575)		 UniProt
Ensembl
RGD		 PMID:36002575 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) RGD PMID:23892723 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24695226)		 UniProt
Ensembl
RGD		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:216,906,836...216,932,046
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:24695226)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO
IEA
IBA		 (PMID:31649195)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:31649195 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO
IEA		 (PMID:22328336)
GO_REF:0000107		 RGD
Ensembl		 PMID:22328336 GO_REF:0000107 NCBI chr14:18,007,342...18,145,980
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:33,087,940...33,208,843
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA		 (PMID:20080593)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080593 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in ISO (PMID:25925578) RGD PMID:25925578 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Pum1 pumilio RNA-binding family member 1 involved_in ISO
IEA		 (PMID:25340845)
GO_REF:0000107		 RGD
Ensembl		 PMID:25340845 GO_REF:0000107 NCBI chr 5:148,120,712...148,238,468
Ensembl chr 5:142,837,127...142,954,039 		JBrowse link
G Pum2 pumilio RNA-binding family member 2 involved_in ISO
IEA		 (PMID:25340845)
GO_REF:0000107		 RGD
Ensembl		 PMID:25340845 GO_REF:0000107 NCBI chr 6:37,182,130...37,262,223
Ensembl chr 6:31,462,872...31,542,976 		JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr20:1,703,723...1,715,465
Ensembl chr20:1,700,905...1,710,249 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO
IEA		 (PMID:24399297)
GO_REF:0000107		 RGD
Ensembl		 PMID:24399297 GO_REF:0000107 NCBI chr 7:60,643,611...60,805,137
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,979,055...68,029,353
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IEA
IBA		 (PMID:30193849)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:30193849 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:161,332,760...161,335,591
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA		 (PMID:22423966)
GO_REF:0000107		 RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:19865078)
GO_REF:0000107		 RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA		 (PMID:26599367), (PMID:28471450)
GO_REF:0000107		 RGD
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
IEA
ISS		 (PMID:28471450)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28471450 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:111,403,624...111,453,703
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr1 toll-like receptor 1 involved_in ISO
IEA		 ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107		 RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:25204797)
GO_REF:0000107		 RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:19865078)
GO_REF:0000107		 RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Flot1 flotillin 1 involved_in ISO
IEA		 (PMID:25204797)
GO_REF:0000107		 RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:19734906)
GO_REF:0000107		 RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:17322885) RGD PMID:17322885 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Trim3 tripartite motif-containing 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:32878999)		 Ensembl
RGD		 PMID:32878999 GO_REF:0000107 NCBI chr 1:169,362,751...169,385,430
Ensembl chr 1:159,944,908...159,973,600 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA		 (PMID:25736436)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,459,613...88,541,215
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24380872)		 UniProt
Ensembl
RGD		 PMID:24380872 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:18622013)
GO_REF:0000107		 RGD
Ensembl		 PMID:18622013 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO
IEA		 (PMID:29038465)
GO_REF:0000107		 RGD
Ensembl		 PMID:29038465 GO_REF:0000107 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (PMID:11528597)
GO_REF:0000107		 RGD
Ensembl		 PMID:11528597 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25860173)		 UniProt
RGD		 PMID:25860173 GO_REF:0000024 NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA		 (PMID:18511497)
GO_REF:0000107		 RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:19734906)
GO_REF:0000107		 RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 RGD PMID:19412184 PMID:22685567 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA		 (PMID:25736436)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,459,613...88,541,215
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO
IEA		 (PMID:28593998)
GO_REF:0000107		 RGD
Ensembl		 PMID:28593998 GO_REF:0000107 NCBI chr19:56,403,816...56,490,901
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21435586)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21045126), (PMID:25238095)
GO_REF:0000024
(PMID:25238095), (PMID:32433612)		 Ensembl
RGD
UniProt		 PMID:21045126 PMID:25238095 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA		 (PMID:32433612)
GO_REF:0000107		 RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:54,354,755...54,373,930
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO
IBA		 (PMID:25848864)
GO_REF:0000033		 RGD
GO_Central		 PMID:25848864 GO_REF:0000033 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:32433612)		 Ensembl
UniProt
RGD		 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA		 (PMID:32433612)
GO_REF:0000107		 RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:54,354,755...54,373,930
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21435586)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25917084)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25917084 GO_REF:0000024 GO_REF:0000107 NCBI chr14:107,651,001...107,698,610
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO
ISS
IEA		 (PMID:25238095)
(PMID:21045126), (PMID:21277849), (PMID:25238095)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:21045126 PMID:21277849 PMID:25238095 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA		 (PMID:18931679)
GO_REF:0000107		 RGD
Ensembl		 PMID:18931679 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO
IEA		 (PMID:38169466)
GO_REF:0000107		 RGD
Ensembl		 PMID:38169466 GO_REF:0000107 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in ISO
IEA		 (PMID:35343654)
GO_REF:0000107		 RGD
Ensembl		 PMID:35343654 GO_REF:0000107 NCBI chr  X:157,238,900...157,245,562
Ensembl chr  X:152,087,444...152,094,272 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 involved_in ISO
IEA		 (PMID:11584270)
GO_REF:0000107		 RGD
Ensembl		 PMID:11584270 GO_REF:0000107 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (PMID:16449650) RGD PMID:16449650 NCBI chr12:24,694,364...24,709,354
Ensembl chr12:19,057,587...19,068,577 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) RGD PMID:20728433 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:160,011,158...160,011,245
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17018642)		 UniProt
RGD		 PMID:17018642 GO_REF:0000024 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO
IEA		 (PMID:15800576)
GO_REF:0000107		 RGD
Ensembl		 PMID:15800576 GO_REF:0000107 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO
IEA		 (PMID:15800576)
GO_REF:0000107		 RGD
Ensembl		 PMID:15800576 GO_REF:0000107 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22801494)		 UniProt
RGD		 PMID:22801494 GO_REF:0000024 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:35353387)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:35353387 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:124,970,363...125,074,919
Ensembl chr 6:119,242,188...119,345,240 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29784761)		 UniProt
RGD		 PMID:29784761 GO_REF:0000024 NCBI chr11:77,519,565...77,548,609
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:29784761)		 UniProt
Ensembl
RGD		 PMID:29784761 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) RGD PMID:23892723 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO
IEA		 (PMID:27824081)
GO_REF:0000107		 RGD
Ensembl		 PMID:27824081 GO_REF:0000107 NCBI chr 1:85,757,271...85,765,089
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr10:63,424,084...63,445,811
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO MGI:5445585 (PMID:28970238) RGD PMID:28970238 NCBI chr 7:22,875,440...22,907,391
Ensembl chr 7:20,991,017...21,019,801 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) RGD PMID:37158982 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:27219021) RGD PMID:27219021 NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO
IEA		 (PMID:27219021)
GO_REF:0000107		 RGD
Ensembl		 PMID:27219021 GO_REF:0000107 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:19289601) RGD PMID:19289601 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) RGD PMID:31134514 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO UniProtKB:P16671 (PMID:20037584) RGD PMID:20037584 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cd36 CD36 molecule involved_in ISO UniProtKB:P05067-PRO_0000000092 (PMID:20037584) RGD PMID:20037584 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO
IEA		 MGI:2150897 (PMID:22659029)
GO_REF:0000107		 RGD
Ensembl		 PMID:22659029 GO_REF:0000107 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO
IEA		 (PMID:20547752)
GO_REF:0000107		 RGD
Ensembl		 PMID:20547752 GO_REF:0000107 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G LOC681325 hypothetical protein LOC681325 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:78,392,551...78,396,164
Ensembl chr  X:74,312,661...74,316,635 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA		 (PMID:20616063)
GO_REF:0000107		 RGD
Ensembl		 PMID:20616063 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mir146a microRNA 146a involved_in ISO (PMID:16885212) RGD PMID:16885212 NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:54,354,755...54,373,930
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clpb ClpB family mitochondrial disaggregase involved_in ISO (PMID:31522117) RGD PMID:31522117 NCBI chr 1:165,440,705...165,563,514
Ensembl chr 1:156,028,930...156,168,788 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO
IEA		 MGI:2442858|MGI:2444773 (PMID:22745163)
GO_REF:0000107		 RGD
Ensembl		 PMID:22745163 GO_REF:0000107 NCBI chr 1:96,101,990...96,146,578
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Mavs mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO MGI:1914320 (PMID:22745163) RGD PMID:22745163 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:31522117) RGD PMID:31522117 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA		 (PMID:31522117)
GO_REF:0000107		 RGD
Ensembl		 PMID:31522117 GO_REF:0000107 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO
IEA		 (PMID:19211564), (PMID:28469175)
GO_REF:0000107		 RGD
Ensembl		 PMID:19211564 PMID:28469175 GO_REF:0000107 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Rnf135 ring finger protein 135 involved_in ISO
ISS		 (PMID:23950712), (PMID:28469175), (PMID:31006531)
UniProtKB:Q8IUD6 (PMID:21147464), (PMID:28469175)
GO_REF:0000024		 RGD
UniProt		 PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531 GO_REF:0000024 NCBI chr10:65,668,441...65,687,671
Ensembl chr10:65,170,560...65,262,804 		JBrowse link
G Trim25 tripartite motif-containing 25 NOT|involved_in ISO (PMID:31006531) RGD PMID:31006531 NCBI chr10:74,310,024...74,328,473
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4a C-type lectin domain family 4, member A involved_in ISO (PMID:22041900) RGD PMID:22041900 NCBI chr 4:158,026,138...158,119,904
Ensembl chr 4:156,414,688...156,432,402 		JBrowse link
G Clec6a-ps1 C-type lectin domain family 6, member A, pseudogene 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:158,225,100...158,244,722
Ensembl chr 4:156,539,408...156,558,605
Ensembl chr 4:156,539,408...156,558,605 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19136564) RGD PMID:19136564 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,828,163...164,838,446
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9655483) RGD PMID:9655483 NCBI chr 4:164,808,722...164,819,865
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
IEA
ISS		 (PMID:9655483)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:9655483 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Klre1 killer cell lectin like receptor E1 involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_REF:0000033
GO_REF:0000107		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:164,719,307...164,727,664
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Klrh1 killer cell lectin-like receptor subfamily H, member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,974,238...164,987,987
Ensembl chr 4:163,288,229...163,300,535 		JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,869,695...164,904,924
Ensembl chr 4:163,183,669...163,218,870 		JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,938,862...164,947,504
Ensembl chr 4:163,252,844...163,261,484 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 4:164,767,377...164,778,453
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO (PMID:19136564), (PMID:22041900) RGD PMID:19136564 PMID:22041900 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:19136564)		 Ensembl
RGD		 PMID:19136564 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IEA
ISS		 (PMID:9655483)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9655483 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9655483)		 UniProt
Ensembl
RGD		 PMID:9655483 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:10383454)
GO_REF:0000107
GO_REF:0000033
(PMID:10549626)		 RGD
Ensembl
GO_Central		 PMID:10383454 PMID:10549626 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA		 (PMID:22187460)
GO_REF:0000107		 RGD
Ensembl		 PMID:22187460 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11894098)
GO_REF:0000107		 RGD
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:17128265) RGD PMID:17128265 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16633345)		 GO_Central
Ensembl
RGD		 PMID:16633345 GO_REF:0000033 GO_REF:0000107 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule involved_in ISO (PMID:25158758) RGD PMID:25158758 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Colec12 collectin sub-family member 12 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:732,950...920,618 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Lgals9 galectin 9 involved_in IMP PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) RGD PMID:21266579 NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rnf170 ring finger protein 170 acts_upstream_of_or_within ISO
IEA		 (PMID:31076723)
GO_REF:0000107		 RGD
Ensembl		 PMID:31076723 GO_REF:0000107 NCBI chr16:72,631,638...72,656,893
Ensembl chr16:65,928,895...65,954,083 		JBrowse link
G Scara3 scavenger receptor class A, member 3 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr15:44,315,422...44,348,416
Ensembl chr15:40,140,161...40,172,894 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) RGD PMID:12471095 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO
IEA		 (PMID:17128265), (PMID:18172197)
GO_REF:0000107		 RGD
Ensembl		 PMID:17128265 PMID:18172197 GO_REF:0000107 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tnf tumor necrosis factor involved_in IMP PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:16633345)		 GO_Central
Ensembl
RGD		 PMID:16633345 GO_REF:0000033 GO_REF:0000107 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA		 (PMID:18082565)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16415873 PMID:18082565 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:210,596,639...210,607,579
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO
IBA		 (PMID:27986454)
GO_REF:0000033		 RGD
GO_Central		 PMID:27986454 GO_REF:0000033 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO
IEA		 (PMID:26189595)
GO_REF:0000107		 RGD
Ensembl		 PMID:26189595 GO_REF:0000107 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ecsit ECSIT signaling integrator involved_in ISO
IEA		 (PMID:25371197)
GO_REF:0000107		 RGD
Ensembl		 PMID:25371197 GO_REF:0000107 NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:20,605,583...20,618,390 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:10549626)
GO_REF:0000033		 RGD
GO_Central		 PMID:10549626 GO_REF:0000033 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in ISO
IEA		 (PMID:17878161)
GO_REF:0000107		 RGD
Ensembl		 PMID:17878161 GO_REF:0000107 NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO
IEA		 (PMID:25636800)
GO_REF:0000107		 RGD
Ensembl		 PMID:25636800 GO_REF:0000107 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Letmd1 LETM1 domain containing 1 acts_upstream_of_or_within ISO
IEA		 (PMID:31980577)
GO_REF:0000107		 RGD
Ensembl		 PMID:31980577 GO_REF:0000107 NCBI chr 7:133,461,920...133,476,592
Ensembl chr 7:131,584,259...131,597,796 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO
IBA		 (PMID:24380872)
GO_REF:0000033		 RGD
GO_Central		 PMID:24380872 GO_REF:0000033 NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO
IEA		 (PMID:28098138)
GO_REF:0000107		 RGD
Ensembl		 PMID:28098138 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO
IEA		 (PMID:25371197)
GO_REF:0000107		 RGD
Ensembl		 PMID:25371197 GO_REF:0000107 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA
IBA		 (PMID:16751103)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16751103 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO
IEA		 MGI:1934018 (PMID:29624734)
GO_REF:0000107		 RGD
Ensembl		 PMID:29624734 GO_REF:0000107 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:7479976)
(PMID:18261938)		 RGD PMID:7479976 PMID:18261938 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA		 (PMID:22187458), (PMID:22187460)
GO_REF:0000107		 RGD
Ensembl		 PMID:22187458 PMID:22187460 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA		 (PMID:25355951)
GO_REF:0000107		 RGD
Ensembl		 PMID:25355951 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:2660793 (PMID:11894098)
GO_REF:0000107		 RGD
Ensembl		 PMID:11894098 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G S100a14 S100 calcium binding protein A14 involved_in ISO
IEA		 (PMID:17625598)
GO_REF:0000107		 RGD
Ensembl		 PMID:17625598 GO_REF:0000107 NCBI chr 2:178,305,976...178,308,004
Ensembl chr 2:176,008,395...176,010,423 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO
IEA		 (PMID:28747347)
GO_REF:0000107		 RGD
Ensembl		 PMID:28747347 GO_REF:0000107 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) RGD PMID:12471095 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:28630139) RGD PMID:28630139 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO
IBA		 (PMID:16751103)
(PMID:11526399)
GO_REF:0000033		 RGD
GO_Central		 PMID:11526399 PMID:16751103 GO_REF:0000033 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:28098138)
(PMID:25549946)
GO_REF:0000033
(PMID:10196138), (PMID:15618008), (PMID:18222170)		 Ensembl
RGD
GO_Central		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 PMID:28098138 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmem126a transmembrane protein 126A acts_upstream_of_or_within ISO
IEA		 (PMID:25549946)
GO_REF:0000107		 RGD
Ensembl		 PMID:25549946 GO_REF:0000107 NCBI chr 1:153,837,015...153,843,192
Ensembl chr 1:144,422,703...144,430,628 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:96,197,019...96,237,357
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO
IEA		 (PMID:18222170)
GO_REF:0000107		 RGD
Ensembl		 PMID:18222170 GO_REF:0000107 NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:25371197) RGD PMID:25371197 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Tril TLR4 interactor with leucine-rich repeats involved_in ISO
IEA
IBA		 (PMID:19710467)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19710467 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:84,252,781...84,257,626
Ensembl chr 4:82,922,328...82,927,172 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA		 (PMID:16751103)
GO_REF:0000107		 RGD
Ensembl		 PMID:16751103 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) RGD PMID:12447442 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in ISO (PMID:14625549), (PMID:17128265) RGD PMID:14625549 PMID:17128265 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA		 (PMID:22187458)
GO_REF:0000107		 RGD
Ensembl		 PMID:22187458 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO
IEA
IBA		 (PMID:12032557)
GO_REF:0000107
GO_REF:0000033
(PMID:14976261)		 RGD
Ensembl
GO_Central		 PMID:12032557 PMID:14976261 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA		 (PMID:19006693)
GO_REF:0000107
(PMID:16415873)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16415873 PMID:19006693 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:210,596,639...210,607,579
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:33718825)		 UniProt
Ensembl
RGD		 PMID:33718825 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in ISO
IEA		 (PMID:12032557)
GO_REF:0000107		 RGD
Ensembl		 PMID:12032557 GO_REF:0000107 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:12032557), (PMID:24942581), (PMID:33718825) RGD PMID:12032557 PMID:24942581 PMID:33718825 NCBI chr  X:30,708,714...30,733,104
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect ISO
IEA		 (PMID:29130391)
GO_REF:0000107		 RGD
Ensembl		 PMID:29130391 GO_REF:0000107 NCBI chr18:73,679,106...73,776,694
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23372731)		 Ensembl
RGD		 PMID:23372731 GO_REF:0000107 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO
IEA		 (PMID:22187458), (PMID:22187460)
GO_REF:0000107		 RGD
Ensembl		 PMID:22187458 PMID:22187460 GO_REF:0000107 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA		 (PMID:23857366)
GO_REF:0000107		 RGD
Ensembl		 PMID:23857366 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO
IEA		 (PMID:16633345)
GO_REF:0000107		 RGD
Ensembl		 PMID:16633345 GO_REF:0000107 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in ISO
IEA
IBA		 (PMID:19006693)
GO_REF:0000107
(PMID:16415873), (PMID:38169466)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16415873 PMID:19006693 PMID:38169466 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:210,596,639...210,607,579
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:20847273) RGD PMID:20847273 NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISO
IEA		 (PMID:16831874)
GO_REF:0000107		 RGD
Ensembl		 PMID:16831874 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Cd86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) RGD PMID:19734906 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:3055991 (PMID:30990796) RGD PMID:30990796 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G LOC100360522 ribosomal protein P1-like acts_upstream_of_negative_effect IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:8,436,843...8,437,954
Ensembl chr17:8,431,465...8,435,348
Ensembl chr 8:8,431,465...8,435,348 		JBrowse link
G Lrrc19 leucine rich repeat containing 19 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:19679103)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19679103 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:114,610,625...114,623,682
Ensembl chr 5:109,497,121...109,507,938 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in ISO
IEA		 (PMID:14607928)
GO_REF:0000107		 RGD
Ensembl		 PMID:14607928 GO_REF:0000107 NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:17906627)		 GO_Central
Ensembl
RGD		 PMID:17906627 GO_REF:0000033 GO_REF:0000107 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:17906627)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:17906627 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:107,929,762...107,963,568 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:3046930|MGI:5501251 (PMID:23728777), (PMID:25124037) RGD PMID:23728777 PMID:25124037 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO (PMID:19136564) RGD PMID:19136564 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand acts_upstream_of ISO (PMID:23907535) RGD PMID:23907535 NCBI chr13:64,710,129...64,713,837 JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 acts_upstream_of_negative_effect IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:62,393,177...62,395,339 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 involved_in ISO
IEA		 (PMID:17906627)
GO_REF:0000107		 RGD
Ensembl		 PMID:17906627 GO_REF:0000107 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:35,517,306...35,623,207 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO (PMID:12471095) RGD PMID:12471095 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tifab TIFA inhibitor acts_upstream_of_negative_effect ISO MGI:5911664 (PMID:26458771) RGD PMID:26458771 NCBI chr17:8,438,622...8,441,750
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
G Tlr1 toll-like receptor 1 involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000002
GO_REF:0000033
(PMID:16893894)		 Ensembl
InterPro
GO_Central
RGD		 PMID:16893894 PMID:16973131 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:1643119 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tlr10 toll-like receptor 10 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:43,758,940...43,768,352
Ensembl chr14:43,406,217...43,413,917 		JBrowse link
G Tlr11 toll-like receptor 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:26,018,987...26,023,426
Ensembl chr15:23,545,408...23,549,849 		JBrowse link
G Tlr12 toll-like receptor 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:146,245,559...146,248,564
Ensembl chr 5:140,959,996...140,964,816 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in IDA
IEA
IBA
ISO
IMP		 GO_REF:0000104
GO_REF:0000002
GO_REF:0000033
(PMID:16893894)		 UniProt
InterPro
GO_Central
RGD		 PMID:16893894 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104, RGD:1643119, RGD:5684896 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:18172197)		 Ensembl
GO_Central
RGD		 PMID:18172197 PMID:16973131 GO_REF:0000033 GO_REF:0000107, RGD:1643119 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IDA
IEA
ISO		 GO_REF:0000107
GO_REF:0000002
(PMID:14607928)		 Ensembl
InterPro
RGD		 PMID:14607928 PMID:16973131 GO_REF:0000002 GO_REF:0000107, RGD:1643119 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in IDA
IEA
IBA
IMP		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033, RGD:1643119, RGD:5684896 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr7 toll-like receptor 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,708,714...30,733,104
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:17128265)		 Ensembl
GO_Central
RGD		 PMID:17128265 PMID:16973131 GO_REF:0000033 GO_REF:0000107, RGD:1643119 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 involved_in ISO
IEA		 (PMID:16306937)
GO_REF:0000107
(PMID:18222170)		 RGD
Ensembl		 PMID:16306937 PMID:18222170 GO_REF:0000107 NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3619211 (PMID:16415873)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:16415873 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:210,596,639...210,607,579
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:28098138) RGD PMID:28098138 NCBI chr10:56,006,243...56,026,357
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISO
IEA		 (PMID:36964784)
GO_REF:0000107		 RGD
Ensembl		 PMID:36964784 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in ISO
IEA		 (PMID:27708357)
GO_REF:0000107		 RGD
Ensembl		 PMID:27708357 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO (PMID:23626692) RGD PMID:23626692 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 (PMID:23626692)
GO_REF:0000107		 RGD
Ensembl		 PMID:23626692 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkce protein kinase C, epsilon involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16757566)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16757566 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO
IEA		 (PMID:30883606)
GO_REF:0000107		 RGD
Ensembl		 PMID:30883606 GO_REF:0000107 NCBI chr 1:268,908,825...269,080,691
Ensembl chr 1:258,923,873...259,093,752 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 RGD PMID:19412184 PMID:22685567 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:36232715) RGD PMID:36232715 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in ISO
ISS		 (PMID:22043923)
GO_REF:0000024		 RGD
UniProt		 PMID:22043923 GO_REF:0000024 NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO
IEA		 (PMID:25636800)
GO_REF:0000107		 RGD
Ensembl		 PMID:25636800 GO_REF:0000107 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 involved_in ISO
IEA
IBA		 (PMID:25636800)
GO_REF:0000002
GO_REF:0000033
(PMID:17658277)		 RGD
InterPro
GO_Central		 PMID:17658277 PMID:25636800 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q9EPW9 (PMID:20037584)		 Ensembl
RGD		 PMID:20037584 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 UniProtKB:Q9QUK6 (PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    immune system process 3132
      activation of immune response 599
        activation of innate immune response 329
          induced systemic resistance, ethylene mediated signaling pathway 0
          induced systemic resistance, jasmonic acid mediated signaling pathway 0
          innate immune response-activating signaling pathway + 301
Path 2
Term Annotations click to browse term
  biological_process 20567
    response to stimulus 11081
      response to external stimulus 2809
        response to external biotic stimulus 1897
          response to other organism 1893
            defense response to other organism 1337
              defense response to symbiont 1111
                innate immune response 1024
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        induced systemic resistance, ethylene mediated signaling pathway 0
                        induced systemic resistance, jasmonic acid mediated signaling pathway 0
                        innate immune response-activating signaling pathway + 301
paths to the root