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ONTOLOGY REPORT - ANNOTATIONS

Term:G-quadruplex RNA binding
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Accession:GO:0002151 term browser browse the term
Definition:Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
Comment:The structures of RNA and DNA G quartets differ regarding sugar conformation so that a protein binding to the RNA structure might not bind to the DNA structure.
Synonyms:exact_synonym: G quadruplex binding;   G quartet RNA binding
 broad_synonym: G quartet binding
 xref: Reactome:R-HSA-9836998 "GRSF1 unwinds quadruplex G regions in RNA"


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G-quadruplex RNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff2 ALF transcription elongation factor 2 enables IBA
ISO
IEA 		GO_REF:0000033
(PMID:19136466)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:19136466 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:147,928,130...148,432,484
Ensembl chr  X:147,928,407...148,429,995 		JBrowse link
G Dhx30 DExH-box helicase 30 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381 		JBrowse link
G Dhx36 DEAH-box helicase 36 enables ISO
ISS
IBA
IEA 		(PMID:18842585), (PMID:20472641), (PMID:21149580), (PMID:21846770), (PMID:22238380), (PMID:24151078), (PMID:24369427), (PMID:25579584), (PMID:26489465), (PMID:27940037)
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:18842585 PMID:20472641 PMID:21149580 PMID:21846770 PMID:22238380 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 enables ISS
ISO
IEA 		GO_REF:0000024
(PMID:18653529), (PMID:21642970), (PMID:25464849), (PMID:26374839)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18653529 PMID:21642970 PMID:25464849 PMID:26374839 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Lin28a lin-28 homolog A enables ISO
IEA 		(PMID:26045559)
GO_REF:0000107 		RGD
Ensembl		 PMID:26045559 GO_REF:0000107 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122 		JBrowse link
G Mcrs1 microspherule protein 1 enables ISO
ISS
IEA 		(PMID:16571602)
GO_REF:0000024
GO_REF:0000002
GO_REF:0000107 		RGD
UniProt
InterPro
Ensembl		 PMID:16571602 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Xrn1 5'-3' exoribonuclease 1 enables ISO (PMID:9049243) RGD PMID:9049243 NCBI chr 8:96,527,871...96,637,385
Ensembl chr 8:96,528,195...96,632,739 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    binding 18100
      nucleic acid binding 3928
        RNA binding 1645
          G-quadruplex RNA binding 7
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