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ONTOLOGY REPORT - ANNOTATIONS

Term:lens development in camera-type eye
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Accession:GO:0002088 term browser browse the term
Definition:The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms:exact_synonym: lens development;   lens development in camera-style eye


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lens development in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:64,415,621...64,590,984
Ensembl chr 3:65,792,223...65,967,631 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:59,618,530...59,623,612
Ensembl chr20:61,157,302...61,161,932 		JBrowse link
G CASP6 caspase 6 ISO RGD PMID:15161922 RGD:2301319 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:10620399 RGD:724665 NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945 		JBrowse link
G CDK4 cyclin dependent kinase 4 ISO RGD PMID:10620399 RGD:724665 NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876 		JBrowse link
G CDON cell adhesion associated, oncogene regulated acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:120,772,160...120,877,529
Ensembl chr11:124,685,084...124,786,091 		JBrowse link
G CRYAA crystallin alpha A acts_upstream_of_or_within
involved_in 		ISO
IEA 		RGD
Ensembl
TreeGrafter		 PMID:8187157 GO_REF:0000107 GO_REF:0000118 RGD:1600991 NCBI chr21:29,414,308...29,480,655
Ensembl chr21:42,782,991...42,786,794 		JBrowse link
G CRYAB crystallin alpha B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272 		JBrowse link
G CRYBA1 crystallin beta A1 involved_in ISO
IEA 		RGD
TreeGrafter		 PMID:2753045 GO_REF:0000118 RGD:1298814 NCBI chr17:27,522,647...27,530,767
Ensembl chr17:28,032,809...28,040,525 		JBrowse link
G CRYBA2 crystallin beta A2 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:106,248,236...106,252,081
Ensembl chr2B:224,841,620...224,844,836 		JBrowse link
G CRYBA4 crystallin beta A4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:7,683,356...7,692,532
Ensembl chr22:25,405,980...25,414,643 		JBrowse link
G CRYBB1 crystallin beta B1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:7,661,085...7,679,640
Ensembl chr22:25,383,681...25,402,158 		JBrowse link
G CRYBG3 crystallin beta-gamma domain containing 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:94,891,281...95,017,694
Ensembl chr 3:101,577,148...101,702,418 		JBrowse link
G CRYGA crystallin gamma A acts_upstream_of_or_within
involved_in 		ISO
IEA 		RGD
Ensembl
TreeGrafter		 PMID:2338125 GO_REF:0000107 GO_REF:0000118 RGD:2303725 NCBI chr2B:95,392,084...95,395,480
Ensembl chr2B:213,515,174...213,518,022 		JBrowse link
G CRYGN crystallin gamma N involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:143,015,345...143,027,237
Ensembl chr 7:155,166,011...155,177,359 		JBrowse link
G CRYGS crystallin gamma S involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:183,569,637...183,576,722
Ensembl chr 3:192,037,607...192,043,486 		JBrowse link
G CTNS cystinosin, lysosomal cystine transporter acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:3,686,903...3,711,857
Ensembl chr17:3,683,575...3,708,253 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987 		JBrowse link
G FAT1 FAT atypical cadherin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,752,261...178,895,038
Ensembl chr 4:190,952,737...191,093,357 		JBrowse link
G FOXE3 forkhead box E3 involved_in ISO (PMID:27218149)
(PMID:17064680) 		UniProt PMID:17064680 PMID:27218149 NCBI chr 1:46,710,791...46,712,771 JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293 		JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:19623612) MGI PMID:19623612 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272 		JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:9620080) MGI PMID:9620080 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJA8 gap junction protein alpha 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:123,352,801...123,355,625
Ensembl chr 1:112,174,365...112,177,893 		JBrowse link
G GJE1 gap junction protein epsilon 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:139,901,021...139,902,784
Ensembl chr 6:143,974,781...143,976,543 		JBrowse link
G LIM2 lens intrinsic membrane protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:48,315,028...48,323,144
Ensembl chr19:57,200,260...57,208,354 		JBrowse link
G LOC100978046 gamma-crystallin D involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:10704279)
(PMID:17652744) 		RGD
TreeGrafter
MGI		 PMID:2338125 PMID:10704279 PMID:17652744 GO_REF:0000118 RGD:2303725 NCBI chr2B:95,352,149...95,356,237
Ensembl chr2B:213,476,336...213,479,279 		JBrowse link
G LOC100978249 beta-crystallin B2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:6,153,824...6,186,786
Ensembl chr22:23,819,784...23,827,265
Ensembl chr22:23,819,784...23,827,265 		JBrowse link
G LOC100978392 gamma-crystallin C involved_in ISO
IEA 		RGD
TreeGrafter		 PMID:2338125 GO_REF:0000118 RGD:2303725 NCBI chr2B:95,359,514...95,361,201
Ensembl chr2B:213,482,830...213,484,517 		JBrowse link
G LOC100978706 gamma-crystallin B acts_upstream_of_or_within
involved_in 		ISO
IEA 		RGD
Ensembl
TreeGrafter		 PMID:2338125 GO_REF:0000107 GO_REF:0000118 RGD:2303725 NCBI chr2B:95,373,199...95,378,131
Ensembl chr2B:213,497,286...213,500,951 		JBrowse link
G MAF MAF bZIP transcription factor acts_upstream_of_or_within ISO (PMID:12835653)
(PMID:10383433)
(PMID:10603348) 		MGI PMID:10383433 PMID:10603348 PMID:12835653 NCBI chr16:60,188,494...60,194,871 JBrowse link
G MED1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118 		JBrowse link
G MIP major intrinsic protein of lens fiber acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:32,459,965...32,465,465
Ensembl chr12:32,713,470...32,718,026 		JBrowse link
G NDP norrin cystine knot growth factor NDP acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:36,399,868...36,424,953
Ensembl chr  X:44,224,161...44,249,067 		JBrowse link
G NHS NHS actin remodeling regulator involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:9,988,584...10,359,110
Ensembl chr  X:17,358,416...17,728,178 		JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G PDS5A PDS5 cohesin associated factor A acts_upstream_of_or_within ISO (PMID:19412548) MGI PMID:19412548 NCBI chr 4:34,149,622...34,303,065
Ensembl chr 4:40,002,869...40,156,698 		JBrowse link
G PDS5B PDS5 cohesin associated factor B acts_upstream_of_or_within ISO (PMID:19412548) MGI PMID:19412548 NCBI chr13:13,843,910...14,033,043
Ensembl chr13:32,337,765...32,462,333 		JBrowse link
G PITX3 paired like homeodomain 3 involved_in ISO (PMID:19007884), (PMID:19334279) UniProt PMID:19007884 PMID:19334279 NCBI chr10:98,833,330...98,846,292 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
G PYGO2 pygopus family PHD finger 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:130,305,547...130,310,270
Ensembl chr 1:133,912,411...133,920,308 		JBrowse link
G SIX3 SIX homeobox 3 involved_in ISO (PMID:11139622) UniProt PMID:11139622 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G SIX5 SIX homeobox 5 acts_upstream_of_or_within ISO (PMID:10802668)
(PMID:10802667) 		MGI PMID:10802667 PMID:10802668 NCBI chr19:42,774,240...42,779,026 JBrowse link
G SLITRK6 SLIT and NTRK like family member 6 acts_upstream_of_or_within ISO (PMID:23543054) MGI PMID:23543054 NCBI chr13:66,990,025...67,003,900
Ensembl chr13:86,161,905...86,164,430 		JBrowse link
G TBC1D20 TBC1 domain family member 20 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:644,646...670,860
Ensembl chr20:414,066...431,032 		JBrowse link
G TBC1D32 TBC1 domain family member 32 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:118,884,928...119,139,138
Ensembl chr 6:123,022,008...123,273,810 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856 		JBrowse link
lens fiber cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFSP1 beaded filament structural protein 1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:17,452,664...17,527,917
Ensembl chr20:17,430,635...17,467,819 		JBrowse link
G BFSP2 beaded filament structural protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:130,470,362...130,543,610
Ensembl chr 3:137,946,969...138,016,584 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:18455718)
(PMID:23136392) 		MGI PMID:18455718 PMID:23136392 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:18455718) MGI PMID:18455718 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:66,992,207...67,107,313
Ensembl chr12:69,829,435...69,878,293 		JBrowse link
G LOC100978706 gamma-crystallin B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2B:95,373,199...95,378,131
Ensembl chr2B:213,497,286...213,500,951 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 acts_upstream_of_or_within ISO (PMID:21118511) MGI PMID:21118511 NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952 		JBrowse link
G TMOD1 tropomodulin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:68,592,195...68,692,001
Ensembl chr 9:96,714,237...96,813,936 		JBrowse link
G VIM vimentin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:17,546,389...17,554,702
Ensembl chr10:17,818,285...17,826,642 		JBrowse link
lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZR1 fizzy and cell division cycle 20 related 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:2,533,172...2,564,301
Ensembl chr19:3,500,117...3,510,867 		JBrowse link
G KDM5B lysine demethylase 5B ISO RGD PMID:24142921 RGD:9587771 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994 		JBrowse link
G LOC100978046 gamma-crystallin D acts_upstream_of_or_within ISO (PMID:17652744) RGD
MGI		 PMID:8575616 PMID:17652744 RGD:1601018 NCBI chr2B:95,352,149...95,356,237
Ensembl chr2B:213,476,336...213,479,279 		JBrowse link
G MAF MAF bZIP transcription factor acts_upstream_of_or_within ISO (PMID:12835653)
(PMID:10383433) 		MGI PMID:10383433 PMID:12835653 NCBI chr16:60,188,494...60,194,871 JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204 		JBrowse link
G PITX3 paired like homeodomain 3 involved_in ISO (PMID:19007884) UniProt PMID:19007884 NCBI chr10:98,833,330...98,846,292 JBrowse link
G PLAAT3 phospholipase A and acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,931,593...58,971,269
Ensembl chr11:62,282,487...62,322,736 		JBrowse link
G SIX3 SIX homeobox 3 involved_in ISO (PMID:12072567) UniProt PMID:12072567 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G SKIL SKI like proto-oncogene acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 ISO RGD PMID:16043861 RGD:2315033 NCBI chr 4:130,529,677...130,601,396
Ensembl chr 4:141,849,343...141,959,849 		JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
G TDRD7 tudor domain containing 7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:68,502,761...68,586,633
Ensembl chr 9:96,640,789...96,708,145 		JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
lens fiber cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:15572692) UniProt PMID:15572692 NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499 		JBrowse link
G ATF4 activating transcription factor 4 involved_in ISO (PMID:10096021), (PMID:10885750), (PMID:11806972) UniProt PMID:10096021 PMID:10885750 PMID:11806972 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249 		JBrowse link
G CRYAA crystallin alpha A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:29,414,308...29,480,655
Ensembl chr21:42,782,991...42,786,794 		JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,259,915...15,292,983
Ensembl chr 1:16,253,513...16,284,787 		JBrowse link
G LOC100978706 gamma-crystallin B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2B:95,373,199...95,378,131
Ensembl chr2B:213,497,286...213,500,951 		JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
G TBC1D20 TBC1 domain family member 20 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:644,646...670,860
Ensembl chr20:414,066...431,032 		JBrowse link
lens induction in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,579,603...88,627,988
Ensembl chr 1:123,633,134...123,677,714 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G POU2F1 POU class 2 homeobox 1 acts_upstream_of_or_within ISO (PMID:17140559) MGI PMID:17140559 NCBI chr 1:142,653,296...142,860,572
Ensembl chr 1:146,439,581...146,633,921 		JBrowse link
G SIX3 SIX homeobox 3 acts_upstream_of_or_within ISO (PMID:17066077) MGI PMID:17066077 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:17140559) MGI PMID:17140559 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
G TFAP2A transcription factor AP-2 alpha acts_upstream_of_or_within ISO (PMID:10571739) MGI PMID:10571739 NCBI chr 6:10,237,834...10,260,843 JBrowse link
lens morphogenesis in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAR3 BCAR3 adaptor protein, NSP family member acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:96,230,498...96,508,028
Ensembl chr 1:94,960,966...95,080,565 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within ISO (PMID:18653562) MGI PMID:18653562 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G CRYAA crystallin alpha A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:29,414,308...29,480,655
Ensembl chr21:42,782,991...42,786,794 		JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:11290300) MGI PMID:11290300 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692 		JBrowse link
G LCTL lactase like involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,495,650...45,514,096
Ensembl chr15:63,769,946...63,787,409 		JBrowse link
G MEIS1 Meis homeobox 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2A:66,494,934...66,633,295
Ensembl chr2A:67,615,941...67,752,958 		JBrowse link
G NECTIN1 nectin cell adhesion molecule 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:114,497,177...114,565,338
Ensembl chr11:118,401,321...118,493,090 		JBrowse link
G NECTIN3 nectin cell adhesion molecule 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:108,223,380...108,354,079
Ensembl chr 3:115,148,481...115,270,507 		JBrowse link
G PITX3 paired like homeodomain 3 involved_in ISO (PMID:19334279) UniProt PMID:19334279 NCBI chr10:98,833,330...98,846,292 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
G SKI SKI proto-oncogene acts_upstream_of_or_within ISO (PMID:17003410) MGI PMID:17003410 NCBI chr 1:944,428...1,029,695
Ensembl chr 1:2,091,620...2,174,080 		JBrowse link
G SOX1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:9512512) MGI PMID:9512512 NCBI chr13:93,023,958...93,269,467 JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in ISO (PMID:18423449) UniProt PMID:18423449 NCBI chr2A:5,699,738...5,711,210 JBrowse link
G TDRD7 tudor domain containing 7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:68,502,761...68,586,633
Ensembl chr 9:96,640,789...96,708,145 		JBrowse link
G TFAP2A transcription factor AP-2 alpha acts_upstream_of_or_within ISO (PMID:18224708), (PMID:9918694) MGI PMID:9918694 PMID:18224708 NCBI chr 6:10,237,834...10,260,843 JBrowse link
negative regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXE3 forkhead box E3 involved_in ISO (PMID:10652278), (PMID:10890982), (PMID:16199865) UniProt PMID:10652278 PMID:10890982 PMID:16199865 NCBI chr 1:46,710,791...46,712,771 JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,182,976...17,286,566
Ensembl chr15:35,439,762...35,536,565 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISO (PMID:29501879) UniProt PMID:29501879 NCBI chr2A:65,380,608...65,503,139
Ensembl chr2A:66,503,260...66,624,840 		JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 involved_in ISO (PMID:29501879) UniProt PMID:29501879 NCBI chr19:35,482,436...35,490,745
Ensembl chr19:44,054,053...44,061,962 		JBrowse link
G SPRY1 sprouty RTK signaling antagonist 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:115,570,788...115,578,824
Ensembl chr 4:126,718,811...126,719,770 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,569,658...61,574,817
Ensembl chr13:80,596,346...80,597,408 		JBrowse link
positive regulation of lens epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXE3 forkhead box E3 involved_in ISO (PMID:22527307)
(PMID:10652278), (PMID:16199865) 		UniProt PMID:10652278 PMID:16199865 PMID:22527307 NCBI chr 1:46,710,791...46,712,771 JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in ISO (PMID:18423449) UniProt PMID:18423449 NCBI chr2A:5,699,738...5,711,210 JBrowse link
positive regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 involved_in ISO (PMID:29501879) UniProt PMID:29501879 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in ISO (PMID:16162653) UniProt PMID:16162653 NCBI chr2B:15,325,094...15,460,908
Ensembl chr2B:148,460,904...148,596,500 		JBrowse link
regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1B cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C acts_upstream_of_or_within ISO (PMID:9784491) MGI PMID:9784491 NCBI chr11:2,908,537...2,911,134 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    developmental process 6695
      anatomical structure development 6275
        lens development in camera-type eye 93
          lens epithelial cell proliferation + 2
          lens fiber cell differentiation + 39
          lens morphogenesis in camera-type eye + 27
Path 2
Term Annotations click to browse term
  biological_process 19315
    developmental process 6695
      anatomical structure development 6275
        multicellular organism development 5035
          system development 4378
            sensory system development 477
              visual system development 471
                eye development 469
                  camera-type eye development 423
                    lens development in camera-type eye 93
                      lens epithelial cell proliferation + 2
                      lens fiber cell differentiation + 39
                      lens morphogenesis in camera-type eye + 27
paths to the root