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ONTOLOGY REPORT - ANNOTATIONS

Term:lens development in camera-type eye
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Accession:GO:0002088 term browser browse the term
Definition:The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms:exact_synonym: lens development;   lens development in camera-style eye


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lens development in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 acts_upstream_of_or_within ISO
IEA 		(PMID:27687499)
GO_REF:0000107 		RGD
Ensembl		 PMID:27687499 GO_REF:0000107 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 acts_upstream_of_or_within ISO
IEA 		MGI:3045749|MGI:5796183 (PMID:26218911)
GO_REF:0000107 		RGD
Ensembl		 PMID:26218911 GO_REF:0000107 NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Casp6 caspase 6 IEP RGD PMID:15161922 RGD:2301319 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cdk2 cyclin dependent kinase 2 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 IEP RGD PMID:10620399 RGD:724665 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated acts_upstream_of_or_within ISO
IEA 		MGI:2653120 (PMID:19754878)
GO_REF:0000107 		RGD
Ensembl		 PMID:19754878 GO_REF:0000107 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Cryaa crystallin, alpha A acts_upstream_of_or_within
involved_in 		IEP
ISO
IBA 		MGI:1858025|MGI:2653028|MGI:88516 (PMID:11687536), (PMID:16439475), (PMID:9023351)
GO_REF:0000033 		RGD
GO_Central		 PMID:9023351 PMID:11687536 PMID:16439475 PMID:8187157 GO_REF:0000033, RGD:1600991 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Cryab crystallin, alpha B acts_upstream_of_or_within ISO
IEA 		MGI:88515 (PMID:16439475)
GO_REF:0000107 		RGD
Ensembl		 PMID:16439475 GO_REF:0000107 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cryba1 crystallin, beta A1 involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:2753045 GO_REF:0000033, RGD:1298814 NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726 		JBrowse link
G Cryba2 crystallin, beta A2 involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:4950379 (PMID:21212184) 		GO_Central
Ensembl
RGD		 PMID:21212184 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:76,447,250...76,457,968
Ensembl chr 9:76,447,251...76,450,460 		JBrowse link
G Cryba4 crystallin, beta A4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221 		JBrowse link
G Crybb1 crystallin, beta B1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344 		JBrowse link
G Crybb2 crystallin, beta B2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:43,569,747...43,579,671
Ensembl chr12:43,569,747...43,579,671 		JBrowse link
G Crybb3 crystallin, beta B3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120 		JBrowse link
G Crybg3 crystallin beta-gamma domain containing 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:40,749,198...40,861,753
Ensembl chr11:40,749,214...40,861,752 		JBrowse link
G Cryga crystallin, gamma A acts_upstream_of_or_within
involved_in 		IEP
ISO
IBA 		MGI:1856493|MGI:1857595 (PMID:6510713), (PMID:6877261), (PMID:7088001), (PMID:8034315)
GO_REF:0000033 		RGD
GO_Central		 PMID:6510713 PMID:6877261 PMID:7088001 PMID:8034315 PMID:2338125 GO_REF:0000033, RGD:2303725 NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within
involved_in 		IEP
ISO
IBA 		MGI:1857597|MGI:3777015 (PMID:12426373), (PMID:18172107), (PMID:8626090)
GO_REF:0000033 		RGD
GO_Central		 PMID:8626090 PMID:12426373 PMID:18172107 PMID:2338125 GO_REF:0000033, RGD:2303725 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Crygc crystallin, gamma C involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:2338125 GO_REF:0000033, RGD:2303725 NCBI chr 9:66,451,591...66,453,626
Ensembl chr 9:66,451,593...66,453,626 		JBrowse link
G Crygd crystallin, gamma D acts_upstream_of_or_within
involved_in 		IEP
IEA
ISO
IBA 		GO_REF:0000107
MGI:1858026|MGI:3762620 (PMID:10704279), (PMID:17652744)
GO_REF:0000033 		Ensembl
RGD
GO_Central		 PMID:10704279 PMID:17652744 PMID:2338125 GO_REF:0000033 GO_REF:0000107, RGD:2303725 NCBI chr 9:66,442,057...66,443,668
Ensembl chr 9:66,442,054...66,444,067 		JBrowse link
G Cryge crystallin, gamma E involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:2338125 GO_REF:0000033, RGD:2303725 NCBI chr 9:66,429,924...66,432,521
Ensembl chr 9:66,429,924...66,433,274 		JBrowse link
G Crygf crystallin, gamma F involved_in IEP
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:2338125 GO_REF:0000033, RGD:2303725 NCBI chr 9:67,448,265...67,450,429
Ensembl chr 9:67,447,954...67,450,429 		JBrowse link
G Crygn crystallin, gamma N involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:10,394,015...10,401,542
Ensembl chr 4:10,394,020...10,401,543 		JBrowse link
G Crygs crystallin, gamma S involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:1861635 (PMID:6877261), (PMID:8034315) 		GO_Central
Ensembl
RGD		 PMID:6877261 PMID:8034315 GO_REF:0000033 GO_REF:0000107 NCBI chr11:78,207,170...78,212,273
Ensembl chr11:78,207,170...78,212,273 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter acts_upstream_of_or_within ISO MGI:2388945 (PMID:21897743) RGD PMID:21897743 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within ISO
IEA 		MGI:2680670 (PMID:14645510)
GO_REF:0000107 		RGD
Ensembl		 PMID:14645510 GO_REF:0000107 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Fat1 FAT atypical cadherin 1 involved_in ISO
IEA 		MGI:2662293 (PMID:26114487)
GO_REF:0000107 		RGD
Ensembl		 PMID:26114487 GO_REF:0000107 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Foxe3 forkhead box E3 involved_in ISS
IEA
ISO 		PMID:17064680
GO_REF:0000107
(PMID:17064680)
GO_REF:0000024
(PMID:27218149) 		Ensembl
RGD
UniProt		 PMID:17064680 PMID:27218149 PMID:17064680 GO_REF:0000024 GO_REF:0000107, RGD:10047226 NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO
IEA 		MGI:3045749|MGI:3768912 (PMID:23136392)
GO_REF:0000107 		RGD
Ensembl		 PMID:23136392 GO_REF:0000107 NCBI chr 7:54,597,182...54,678,656
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO
IEA 		MGI:2181200 (PMID:19623612)
GO_REF:0000107 		RGD
Ensembl		 PMID:19623612 GO_REF:0000107 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (PMID:9620080) RGD PMID:9620080 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja8 gap junction protein, alpha 8 acts_upstream_of_or_within ISO MGI:1857499 (PMID:6877261) RGD PMID:6877261 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456 		JBrowse link
G Gje1 gap junction protein, epsilon 1 acts_upstream_of_or_within ISO
IEA 		MGI:3529958 (PMID:18385072)
GO_REF:0000107 		RGD
Ensembl		 PMID:18385072 GO_REF:0000107 NCBI chr 1:9,085,789...9,088,204
Ensembl chr 1:9,086,348...9,088,138 		JBrowse link
G Lim2 lens intrinsic membrane protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:1862040 (PMID:6510713), (PMID:6877261), (PMID:7088001), (PMID:8812411)
GO_REF:0000107 		RGD
Ensembl		 PMID:6510713 PMID:6877261 PMID:7088001 PMID:8812411 GO_REF:0000107 NCBI chr 1:93,837,597...93,843,769
Ensembl chr 1:93,837,597...93,843,769 		JBrowse link
G Maf MAF bZIP transcription factor acts_upstream_of_or_within ISO MGI:2148635|MGI:2148636|MGI:2148637 (PMID:10383433), (PMID:10603348), (PMID:12835653) RGD PMID:10383433 PMID:10603348 PMID:12835653 NCBI chr19:60,259,200...60,622,145
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:11724781) 		UniProt
Ensembl
RGD		 PMID:11724781 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mip major intrinsic protein of lens fiber acts_upstream_of_or_within ISO MGI:1857105 (PMID:7333462) RGD PMID:7333462 NCBI chr 7:643,502...653,121
Ensembl chr 7:647,315...654,400 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO
IEA 		MGI:2676199 (PMID:15716406)
GO_REF:0000107 		RGD
Ensembl		 PMID:15716406 GO_REF:0000107 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nhs NHS actin remodeling regulator involved_in
acts_upstream_of_or_within 		IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
MGI:1861111 (PMID:8282045) 		GO_Central
Ensembl
RGD		 PMID:8282045 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:32,553,300...32,892,961
Ensembl chr  X:32,552,026...32,889,992 		JBrowse link
G Pax6 paired box 6 acts_upstream_of_or_within ISO
IEA 		MGI:2156742 (PMID:6877261)
GO_REF:0000107 		RGD
Ensembl		 PMID:6877261 GO_REF:0000107 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pds5a PDS5 cohesin associated factor A acts_upstream_of_or_within ISO MGI:3722688 (PMID:19412548) RGD PMID:19412548 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669 		JBrowse link
G Pds5b PDS5 cohesin associated factor B acts_upstream_of_or_within ISO MGI:3722688 (PMID:19412548) RGD PMID:19412548 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19007884), (PMID:19334279) 		UniProt
Ensembl
RGD		 PMID:19007884 PMID:19334279 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO
IEA 		(PMID:8812486)
GO_REF:0000107 		RGD
Ensembl		 PMID:8812486 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Pygo2 pygopus family PHD finger 2 acts_upstream_of_or_within ISO
IEA 		MGI:3712856 (PMID:17425782)
GO_REF:0000107 		RGD
Ensembl		 PMID:17425782 GO_REF:0000107 NCBI chr 2:174,849,670...174,854,758
Ensembl chr 2:174,849,936...174,854,758 		JBrowse link
G Six3 SIX homeobox 3 involved_in ISO (PMID:11139622) RGD PMID:11139622 NCBI chr 6:9,039,017...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Six5 SIX homeobox 5 acts_upstream_of_or_within ISO
IEA 		MGI:2148689|MGI:2148692 (PMID:10802667), (PMID:10802668)
GO_REF:0000107 		RGD
Ensembl		 PMID:10802667 PMID:10802668 GO_REF:0000107 NCBI chr 1:78,740,812...78,745,890
Ensembl chr 1:78,741,367...78,745,890 		JBrowse link
G Slitrk6 SLIT and NTRK-like family, member 6 acts_upstream_of_or_within ISO
IEA 		MGI:4417931 (PMID:23543054)
GO_REF:0000107 		RGD
Ensembl		 PMID:23543054 GO_REF:0000107 NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 acts_upstream_of_or_within ISO
IEA 		MGI:1856684 (PMID:24239381)
GO_REF:0000107 		RGD
Ensembl		 PMID:24239381 GO_REF:0000107 NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO
IEA 		MGI:4440463 (PMID:20159594)
GO_REF:0000107 		RGD
Ensembl		 PMID:20159594 GO_REF:0000107 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 acts_upstream_of_or_within ISO
IEA 		(PMID:11641223)
GO_REF:0000107 		RGD
Ensembl		 PMID:11641223 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO
IEA 		(PMID:11641223)
GO_REF:0000107 		RGD
Ensembl		 PMID:11641223 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
lens fiber cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bfsp1 beaded filament structural protein 1 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
(PMID:15037121)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:15037121 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337 		JBrowse link
G Bfsp2 beaded filament structural protein 2 acts_upstream_of_or_within ISO MGI:2671074 (PMID:15037121), (PMID:17065509) RGD PMID:15037121 PMID:17065509 NCBI chr 8:104,006,226...104,063,399
Ensembl chr 8:104,006,226...104,063,399 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within ISO MGI:3777015 (PMID:18172107) RGD PMID:18172107 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:3044679|MGI:3045749|MGI:95524 (PMID:18455718), (PMID:23136392) RGD PMID:18455718 PMID:23136392 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:95523 (PMID:18455718) RGD PMID:18455718 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 acts_upstream_of_or_within ISO
IEA 		MGI:3045749|MGI:3768912|MGI:97385 (PMID:23136392)
GO_REF:0000107 		RGD
Ensembl		 PMID:23136392 GO_REF:0000107 NCBI chr 7:54,597,182...54,678,656
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 acts_upstream_of_or_within ISO MGI:2386105 (PMID:21118511) RGD PMID:21118511 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q6NVD9 (PMID:23144950) 		Ensembl
RGD		 PMID:23144950 GO_REF:0000107 NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956 		JBrowse link
G Vim vimentin acts_upstream_of_or_within ISO (PMID:15037121) RGD PMID:15037121 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crygd crystallin, gamma D acts_upstream_of_or_within IDA
IEA
ISO 		GO_REF:0000107
MGI:3762620 (PMID:17652744) 		Ensembl
RGD		 PMID:17652744 PMID:8575616 GO_REF:0000107, RGD:1601018 NCBI chr 9:66,442,057...66,443,668
Ensembl chr 9:66,442,054...66,444,067 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 acts_upstream_of_or_within ISO
IEA 		(PMID:17215516)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215516 GO_REF:0000107 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
G Kdm5b lysine demethylase 5B IEP RGD PMID:24142921 RGD:9587771 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Maf MAF bZIP transcription factor involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:2148636|MGI:2148637 (PMID:10383433), (PMID:12835653) 		GO_Central
RGD		 PMID:10383433 PMID:12835653 GO_REF:0000033 NCBI chr19:60,259,200...60,622,145
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in IEA
ISO 		GO_REF:0000107
(PMID:20181838) 		Ensembl
RGD		 PMID:20181838 GO_REF:0000107 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of_or_within ISO
IEA 		MGI:1100860 (PMID:23136392)
GO_REF:0000107 		RGD
Ensembl		 PMID:23136392 GO_REF:0000107 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISO
IEA 		(PMID:19007884)
GO_REF:0000107 		RGD
Ensembl		 PMID:19007884 GO_REF:0000107 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:85,022,297...85,041,999
Ensembl chr11:71,517,493...71,527,020 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 involved_in ISS
ISO 		GO_REF:0000024
(PMID:33854238) 		UniProt
RGD		 PMID:33854238 GO_REF:0000024 NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:204,782,729...204,817,667 		JBrowse link
G Six3 SIX homeobox 3 involved_in ISO (PMID:12072567) RGD PMID:12072567 NCBI chr 6:9,039,017...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO
IEA 		(PMID:17215516)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215516 GO_REF:0000107 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 IEP RGD PMID:16043861 RGD:2315033 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO
IEA 		(PMID:17215516)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215516 GO_REF:0000107 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISO
IBA
IEA
ISS 		(PMID:21436445)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
GO_Central
Ensembl
UniProt		 PMID:21436445 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:65,034,317...65,108,165
Ensembl chr 5:60,238,678...60,312,544 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO
IEA 		(PMID:17215516)
GO_REF:0000107 		RGD
Ensembl		 PMID:17215516 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
lens fiber cell morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 involved_in ISO (PMID:15572692) RGD PMID:15572692 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:10096021), (PMID:10885750), (PMID:11806972) 		UniProt
Ensembl
RGD		 PMID:10096021 PMID:10885750 PMID:11806972 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cryaa crystallin, alpha A acts_upstream_of_or_within ISO MGI:3665275|MGI:3777403 (PMID:16799046), (PMID:18056999) RGD PMID:16799046 PMID:18056999 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Crygb crystallin, gamma B acts_upstream_of_or_within ISO MGI:1857597 (PMID:12426373), (PMID:8626090) RGD PMID:8626090 PMID:12426373 NCBI chr 9:66,461,460...66,463,520
Ensembl chr 9:66,461,460...66,463,520 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO
IEA 		(PMID:18948590)
GO_REF:0000107 		RGD
Ensembl		 PMID:18948590 GO_REF:0000107 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO
IEA 		(PMID:11850194)
GO_REF:0000107
(PMID:10080188) 		RGD
Ensembl		 PMID:10080188 PMID:11850194 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 acts_upstream_of_or_within ISO
IEA 		MGI:1856684 (PMID:24239381)
GO_REF:0000107 		RGD
Ensembl		 PMID:24239381 GO_REF:0000107 NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121 		JBrowse link
lens induction in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA 		MGI:1857137 (PMID:9851982)
GO_REF:0000107 		RGD
Ensembl		 PMID:9851982 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20579985) 		Ensembl
RGD		 PMID:20579985 GO_REF:0000107 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:20579985) RGD PMID:20579985 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 acts_upstream_of_or_within ISO MGI:98364 (PMID:17140559) RGD PMID:17140559 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within ISO MGI:3693322 (PMID:17066077) RGD PMID:17066077 NCBI chr 6:9,039,017...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO MGI:101898 (PMID:17140559) RGD PMID:17140559 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:1888387 (PMID:10571739) RGD PMID:10571739 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
lens morphogenesis in camera-type eye term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar3 BCAR3 adaptor protein, NSP family member acts_upstream_of_or_within ISO
IEA 		MGI:4359826 (PMID:19365570)
GO_REF:0000107 		RGD
Ensembl		 PMID:19365570 GO_REF:0000107 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:3045749|MGI:3696062 (PMID:18653562) RGD PMID:18653562 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cryaa crystallin, alpha A acts_upstream_of_or_within ISO MGI:1858023|MGI:3665274|MGI:3665275 (PMID:16799046), (PMID:8812430) RGD PMID:8812430 PMID:16799046 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO
IEA 		MGI:2148567|MGI:3045749 (PMID:16102745)
GO_REF:0000107 		RGD
Ensembl		 PMID:16102745 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:11290300) RGD PMID:11290300 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Lctl lactase-like involved_in ISO
IEA 		(PMID:29425878)
GO_REF:0000107 		RGD
Ensembl		 PMID:29425878 GO_REF:0000107 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357 		JBrowse link
G Meis1 Meis homeobox 1 acts_upstream_of_or_within ISO
IEA 		MGI:3029063 (PMID:14713950)
GO_REF:0000107 		RGD
Ensembl		 PMID:14713950 GO_REF:0000107 NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within ISO
IEA 		MGI:3605480 (PMID:15728677)
GO_REF:0000107 		RGD
Ensembl		 PMID:15728677 GO_REF:0000107 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 acts_upstream_of_or_within ISO
IEA 		MGI:3605481 (PMID:15728677)
GO_REF:0000107 		RGD
Ensembl		 PMID:15728677 GO_REF:0000107 NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519 		JBrowse link
G Pitx3 paired-like homeodomain 3 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19334279) 		UniProt
Ensembl
RGD		 PMID:19334279 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO
IEA 		(PMID:10080188)
GO_REF:0000107 		RGD
Ensembl		 PMID:10080188 GO_REF:0000107 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Ski Ski proto-oncogene acts_upstream_of_or_within ISO MGI:2177555 (PMID:17003410) RGD PMID:17003410 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:2137412 (PMID:9512512) RGD PMID:9512512 NCBI chr16:77,135,577...77,139,592
Ensembl chr16:77,137,584...77,138,762 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18423449) 		UniProt
Ensembl
RGD		 PMID:18423449 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Tdrd7 tudor domain containing 7 involved_in ISS
ISO
IBA
IEA 		GO_REF:0000024
(PMID:21436445)
GO_REF:0000033
GO_REF:0000107 		UniProt
RGD
GO_Central
Ensembl		 PMID:21436445 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:65,034,317...65,108,165
Ensembl chr 5:60,238,678...60,312,544 		JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:2176682 (PMID:18224708), (PMID:9918694) RGD PMID:9918694 PMID:18224708 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
negative regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISS
IEA
ISO 		PMID:16199865
GO_REF:0000107
(PMID:10652278), (PMID:10890982), (PMID:16199865) 		Ensembl
RGD		 PMID:10652278 PMID:10890982 PMID:16199865 PMID:16199865 GO_REF:0000107, RGD:10047273 NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO
IEA 		(PMID:29501879)
GO_REF:0000107 		RGD
Ensembl		 PMID:29501879 GO_REF:0000107 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:29501879) 		UniProt
RGD		 PMID:29501879 GO_REF:0000024 NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 involved_in ISO (PMID:29501879) RGD PMID:29501879 NCBI chr 1:84,458,779...84,470,425
Ensembl chr 1:84,459,314...84,470,249 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 involved_in ISO
IEA 		(PMID:29501879)
GO_REF:0000107 		RGD
Ensembl		 PMID:29501879 GO_REF:0000107 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO
IEA 		(PMID:29501879)
GO_REF:0000107 		RGD
Ensembl		 PMID:29501879 GO_REF:0000107 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
positive regulation of lens epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxe3 forkhead box E3 involved_in ISS
ISO
IEA 		PMID:16199865
(PMID:22527307)
(PMID:10652278), (PMID:16199865)
GO_REF:0000107 		RGD
Ensembl		 PMID:10652278 PMID:16199865 PMID:22527307 PMID:16199865 PMID:22527307 GO_REF:0000107, RGD:10047273, RGD:10047255 NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454 		JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:18423449)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18423449 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
positive regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:29501879)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:29501879 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 involved_in ISO
IEA 		(PMID:16162653)
GO_REF:0000107 		RGD
Ensembl		 PMID:16162653 GO_REF:0000107 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
regulation of lens fiber cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B acts_upstream_of_or_within ISO MGI:104564 (PMID:9784491) RGD PMID:9784491 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C acts_upstream_of_or_within ISO
IEA 		MGI:104565 (PMID:9784491)
GO_REF:0000107 		RGD
Ensembl		 PMID:9784491 GO_REF:0000107 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        lens development in camera-type eye 97
          lens epithelial cell proliferation + 2
          lens fiber cell differentiation + 40
          lens morphogenesis in camera-type eye + 27
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            sensory system development 508
              visual system development 501
                eye development 498
                  camera-type eye development 447
                    lens development in camera-type eye 97
                      lens epithelial cell proliferation + 2
                      lens fiber cell differentiation + 40
                      lens morphogenesis in camera-type eye + 27
paths to the root