ONTOLOGY REPORT - ANNOTATIONS
Term: inner acrosomal membrane
Accession: GO:0002079
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Definition: The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
Comment: Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.
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Cd46
CD46 molecule
located_in
IDA IEA
GO_REF:0000044
UniProt RGD
PMID:15215199
GO_REF:0000044, RGD:2293559
NCBI chr13:109,104,122...109,134,903
Ensembl chr13:106,574,858...106,660,445
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Cd46l1
CD46 molecule like 1
located_in
IEA
GO_REF:0000044
UniProt
GO_REF:0000044
NCBI chr20:34,538,996...34,539,997
Ensembl chr20:33,996,224...33,997,432
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Eqtn
equatorin
located_in is_active_in
ISS ISO IBA
GO_REF:0000024 (PMID:19605790), (PMID:20032212) GO_REF:0000033
UniProt RGD GO_Central
PMID:19605790 PMID:20032212
GO_REF:0000024 GO_REF:0000033
NCBI chr 5:114,851,981...114,880,683
Ensembl chr 5:109,728,999...109,761,840
G
Izumo3
IZUMO family member 3
located_in
ISO IEA
(PMID:34114279) GO_REF:0000107
RGD Ensembl
PMID:34114279
GO_REF:0000107
NCBI chr 5:111,990,148...111,992,826
Ensembl chr 5:106,874,351...106,877,004
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Spaca4
sperm acrosome associated 4
located_in
ISO
(PMID:37377732) (PMID:34556579)
RGD
PMID:34556579 PMID:37377732
NCBI chr 1:96,195,514...96,196,187
Ensembl chr 1:96,195,315...96,196,237
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Tmem190
transmembrane protein 190
is_active_in located_in
IBA ISO
GO_REF:0000033 (PMID:21273369)
GO_Central RGD
PMID:21273369
GO_REF:0000033
NCBI chr 1:78,091,506...78,093,736
Ensembl chr 1:69,062,366...69,065,238
G
Tmem225
transmembrane protein 225
located_in
ISO
(PMID:25605614)
RGD
PMID:25605614
NCBI chr 8:49,394,638...49,397,196
Ensembl chr 8:40,497,483...40,500,041
G
Trip11
thyroid hormone receptor interactor 11
located_in
IDA
PMID:21337470
MGI
PMID:21337470
RGD:8655529
NCBI chr 6:126,760,263...126,832,619
Ensembl chr 6:120,998,733...121,067,781
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