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ONTOLOGY REPORT - ANNOTATIONS


Term:inner acrosomal membrane
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Accession:GO:0002079 term browser browse the term
Definition:The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
Comment:Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.



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inner acrosomal membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule located_in IDA
IEA
GO_REF:0000044 UniProt
RGD
PMID:15215199 GO_REF:0000044, RGD:2293559 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd46l1 CD46 molecule like 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr20:33,996,404...33,997,405 JBrowse link
G Eqtn equatorin located_in
is_active_in
ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:19605790), (PMID:20032212)
UniProt
GO_Central
RGD
PMID:19605790 PMID:20032212 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:109,734,495...109,762,048 JBrowse link
G Izumo3 IZUMO family member 3 located_in ISO
IEA
(PMID:34114279)
GO_REF:0000107
RGD
Ensembl
PMID:34114279 GO_REF:0000107 NCBI chr 5:106,874,321...106,876,978 JBrowse link
G Spaca4 sperm acrosome associated 4 located_in ISO (PMID:37377732)
(PMID:34556579)
RGD PMID:34556579 PMID:37377732 NCBI chr 1:96,195,514...96,196,187 JBrowse link
G Tmem190 transmembrane protein 190 is_active_in
located_in
IBA
ISO
GO_REF:0000033
(PMID:21273369)
GO_Central
RGD
PMID:21273369 GO_REF:0000033 NCBI chr 1:69,062,709...69,064,938 JBrowse link
G Tmem225 transmembrane protein 225 located_in ISO (PMID:25605614) RGD PMID:25605614 NCBI chr 8:40,497,483...40,500,041 JBrowse link
G Trip11 thyroid hormone receptor interactor 11 located_in IDA PMID:21337470 MGI PMID:21337470 RGD:8655529 NCBI chr 6:120,995,242...121,067,693 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      cytoplasm 12254
        cytoplasmic vesicle 2065
          cytoplasmic vesicle membrane 896
            inner acrosomal membrane 8
Path 2
Term Annotations click to browse term
  cellular_component 21321
    cellular anatomical structure 21026
      intracellular anatomical structure 15547
        intracellular organelle 13828
          intracellular membrane-bounded organelle 12253
            intracellular vesicle 2074
              cytoplasmic vesicle 2065
                secretory vesicle 746
                  secretory granule 479
                    secretory granule membrane 103
                      acrosomal membrane 35
                        inner acrosomal membrane 8
paths to the root