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ONTOLOGY REPORT - ANNOTATIONS

Term:chondrocyte development
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Accession:GO:0002063 term browser browse the term
Definition:The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


show annotations for term's descendants           Sort by:
chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856465 (PMID:9664687) 		Ensembl
RGD		 PMID:9664687 GO_REF:0000107 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO
IEA 		(PMID:9442116)
GO_REF:0000107 		RGD
Ensembl		 PMID:9442116 GO_REF:0000107 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 acts_upstream_of_or_within ISO MGI:3806990 (PMID:18539921) RGD PMID:18539921 NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126 		JBrowse link
G Chst11 carbohydrate sulfotransferase 11 acts_upstream_of_or_within ISO MGI:3768254 (PMID:16079159) RGD PMID:16079159 NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5007063 (PMID:22280990) 		Ensembl
RGD		 PMID:22280990 GO_REF:0000107 NCBI chr 1:129,100,088...129,161,167
Ensembl chr 1:129,100,041...129,161,081 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain acts_upstream_of_or_within ISO MGI:1856399 (PMID:4100752) RGD PMID:4100752 NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264 		JBrowse link
G Comp cartilage oligomeric matrix protein acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3758741|MGI:5550566 (PMID:17588960), (PMID:22006726) 		Ensembl
RGD		 PMID:17588960 PMID:22006726 GO_REF:0000107 NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605 		JBrowse link
G Ecm1 extracellular matrix protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:20138147) 		Ensembl
RGD		 PMID:20138147 GO_REF:0000107 NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2183829 (PMID:12865332) RGD PMID:12865332 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Fgf18 fibroblast growth factor 18 acts_upstream_of_or_within ISO MGI:2178751 (PMID:17014841) RGD PMID:17014841 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:25107907) 		Ensembl
RGD		 PMID:25107907 GO_REF:0000107 NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:82,673,140...82,676,844 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO MGI:5007248 (PMID:21606205) RGD PMID:21606205 NCBI chr13:97,502,040...97,547,155
Ensembl chr13:97,494,275...97,543,587 		JBrowse link
G Msx2 msh homeobox 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1926381 (PMID:10742104) 		Ensembl
RGD		 PMID:10742104 GO_REF:0000107 NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945 		JBrowse link
G Rarg retinoic acid receptor, gamma involved_in IEA
ISO 		GO_REF:0000107
(PMID:19389355) 		Ensembl
RGD		 PMID:19389355 GO_REF:0000107 NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889 		JBrowse link
G Runx2 RUNX family transcription factor 2 acts_upstream_of_or_within ISO MGI:2176466 (PMID:10213384) RGD PMID:10213384 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3810257 (PMID:18729207) 		Ensembl
RGD		 PMID:18729207 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Shox2 SHOX homeobox 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3605739 (PMID:17481601) 		Ensembl
RGD		 PMID:17481601 GO_REF:0000107 NCBI chr 2:153,524,324...153,537,571
Ensembl chr 2:153,527,571...153,537,161 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3575405 (PMID:17591962), (PMID:24505141) 		Ensembl
RGD		 PMID:17591962 PMID:24505141 GO_REF:0000107 NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:18415932) 		Ensembl
RGD		 PMID:18415932 GO_REF:0000107 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
G Sulf1 sulfatase 1 involved_in IEA
ISO
ISS 		GO_REF:0000104
(PMID:20479257)
GO_REF:0000024 		UniProt
RGD		 PMID:20479257 GO_REF:0000024 GO_REF:0000104 NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643 		JBrowse link
G Sulf2 sulfatase 2 involved_in IEA
ISO 		GO_REF:0000104
(PMID:20479257)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:20479257 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651 		JBrowse link
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinh1 serpin family H member 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2176070|MGI:5505265 (PMID:22492985) 		Ensembl
RGD		 PMID:22492985 GO_REF:0000107 NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856877 (PMID:21788370) 		Ensembl
RGD		 PMID:21788370 GO_REF:0000107 NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936 		JBrowse link
chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23958822) 		Ensembl
RGD		 PMID:23958822 GO_REF:0000107 NCBI chr 7:86,265,651...86,544,488
Ensembl chr 7:86,259,900...86,544,567 		JBrowse link
G Gusb glucuronidase, beta acts_upstream_of_or_within ISO (PMID:29747998), (PMID:31974587) RGD PMID:29747998 PMID:31974587 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Mex3c mex-3 RNA binding family member C acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3764947 (PMID:22357625) 		Ensembl
RGD		 PMID:22357625 GO_REF:0000107 NCBI chr18:69,442,850...69,463,843
Ensembl chr18:69,442,152...69,463,846 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21367821)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21367821 GO_REF:0000024 GO_REF:0000107 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
growth plate cartilage chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col27a1 collagen type XXVII alpha 1 chain acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5315593 (PMID:22206015) 		Ensembl
RGD		 PMID:22206015 GO_REF:0000107 NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:81,661,685...81,781,502 		JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2135614 (PMID:26496357) 		Ensembl
RGD		 PMID:26496357 GO_REF:0000107 NCBI chr 8:115,801,335...115,869,812
Ensembl chr 8:115,801,396...115,870,392 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272 		JBrowse link
growth plate cartilage chondrocyte growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst5 cystatin D involved_in ISO MGI:3629665 (PMID:16680148) RGD PMID:16680148 NCBI chr 3:158,033,791...158,038,345
Ensembl chr 3:158,033,791...158,038,345 		JBrowse link
G Ctdspl2 CTD small phosphatase like 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:38886174) 		UniProt
RGD		 PMID:38886174 GO_REF:0000024 NCBI chr 3:129,365,709...129,424,232
Ensembl chr 3:129,368,938...129,424,232 		JBrowse link
G Rarg retinoic acid receptor, gamma involved_in IEA
ISO 		GO_REF:0000107
(PMID:19389355) 		Ensembl
RGD		 PMID:19389355 GO_REF:0000107 NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:22421045)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:22421045 GO_REF:0000024 GO_REF:0000107 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2384513 (PMID:21420963) 		Ensembl
RGD		 PMID:21420963 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matn1 matrilin 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2153042|MGI:3663272 (PMID:16877353) 		Ensembl
RGD		 PMID:16877353 GO_REF:0000107 NCBI chr 5:148,401,364...148,411,256
Ensembl chr 5:148,401,620...148,411,256 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:90087) RGD PMID:90087 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Rflna refilin A acts_upstream_of_or_within ISO MGI:1923816 (PMID:24436304) RGD PMID:24436304 NCBI chr12:37,294,643...37,323,373
Ensembl chr12:37,294,643...37,303,535 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:1920371 (PMID:24436304)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:24436304 GO_REF:0000033 GO_REF:0000107 NCBI chr10:61,391,947...61,398,224
Ensembl chr10:61,390,659...61,398,224 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa11 homeobox A11 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:82,673,140...82,676,844 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO 		GO_REF:0000107
(PMID:29503843) 		Ensembl
RGD		 PMID:29503843 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3579503 (PMID:19623616) 		Ensembl
RGD		 PMID:19623616 GO_REF:0000107 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575 		JBrowse link
G Rflnb refilin B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:61,391,947...61,398,224
Ensembl chr10:61,390,659...61,398,224 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular developmental process 4933
        cell development 3418
          chondrocyte development 38
            chondrocyte development involved in endochondral bone morphogenesis + 11
            chondrocyte hypertrophy + 9
            chondrocyte morphogenesis + 1
            negative regulation of chondrocyte development + 3
            positive regulation of chondrocyte development + 2
            regulation of chondrocyte development + 6
Path 2
Term Annotations click to browse term
  biological_process 19315
    developmental process 7255
      anatomical structure development 6748
        multicellular organism development 5415
          system development 4702
            skeletal system development 599
              cartilage development 247
                chondrocyte differentiation 133
                  chondrocyte development 38
                    chondrocyte development involved in endochondral bone morphogenesis + 11
                    chondrocyte hypertrophy + 9
                    chondrocyte morphogenesis + 1
                    negative regulation of chondrocyte development + 3
                    positive regulation of chondrocyte development + 2
                    regulation of chondrocyte development + 6
paths to the root