ONTOLOGY REPORT - ANNOTATIONS
Term: regulation of angiotensin levels in blood
Accession: GO:0002002
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Definition: The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.
Synonyms: exact_synonym: regulation of blood angiotensin level
related_synonym: control of angiotensin levels in blood; control of blood angiotensin level
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Cpa3
carboxypeptidase A3
acts_upstream_of_or_within
ISO
MGI:96940 (PMID:15173164)
RGD
PMID:15173164
NCBI chr 2:102,712,483...102,744,219
Ensembl chr 2:102,712,589...102,744,203
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Kcnn4
potassium calcium-activated channel subfamily N member 4
IMP
RGD
PMID:25715999
RGD:401794570
NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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Ndst2
N-deacetylase and N-sulfotransferase 2
acts_upstream_of_or_within
ISO
(PMID:15173164)
RGD
PMID:15173164
NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
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Ace
angiotensin I converting enzyme
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:11432860), (PMID:1320019), (PMID:4322742), (PMID:6270633) (PMID:11303049), (PMID:14757757), (PMID:18158355), (PMID:27649628)
UniProt Ensembl RGD
PMID:1320019 PMID:4322742 PMID:6270633 PMID:11303049 PMID:11432860 PMID:14757757 PMID:18158355 PMID:27649628 More...
GO_REF:0000024 GO_REF:0000107
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ace2
angiotensin converting enzyme 2
involved_in
ISO IEA
UniProtKB:Q9BYF1 (PMID:18263657), (PMID:20357030), (PMID:23462816) GO_REF:0000107
RGD Ensembl
PMID:18263657 PMID:20357030 PMID:23462816
GO_REF:0000107
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Anpep
alanyl aminopeptidase, membrane
involved_in
ISO IEA
(PMID:8876246) GO_REF:0000107
RGD Ensembl
PMID:8876246
GO_REF:0000107
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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Atp6ap2
ATPase H+ transporting accessory protein 2
involved_in
ISO IEA
(PMID:12045255), (PMID:15746149) GO_REF:0000107
RGD Ensembl
PMID:12045255 PMID:15746149
GO_REF:0000107
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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Cpa3
carboxypeptidase A3
involved_in
ISO IEA
(PMID:15173164) GO_REF:0000107
RGD Ensembl
PMID:15173164
GO_REF:0000107
NCBI chr 2:102,712,483...102,744,219
Ensembl chr 2:102,712,589...102,744,203
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Enpep
glutamyl aminopeptidase
involved_in
ISO IEA
MGI:2182774 (PMID:16889841), (PMID:19228697) GO_REF:0000107
RGD Ensembl
PMID:16889841 PMID:19228697
GO_REF:0000107
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
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Mme
membrane metallo-endopeptidase
involved_in
ISO IEA
MGI:1917258|MGI:2137696 (PMID:27649628), (PMID:28559246) GO_REF:0000107
RGD Ensembl
PMID:27649628 PMID:28559246
GO_REF:0000107
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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Prcp
prolylcarboxypeptidase
involved_in
ISO IEA
(PMID:27649628) GO_REF:0000107
RGD Ensembl
PMID:27649628
GO_REF:0000107
NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
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Prep
prolyl endopeptidase
involved_in
ISO IEA
(PMID:27649628) GO_REF:0000107
RGD Ensembl
PMID:27649628
GO_REF:0000107
NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466
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Ren
renin
involved_in acts_upstream_of_or_within
IDA ISO IBA
(PMID:12045255) GO_REF:0000033 MGI:2136642 (PMID:10617578) (PMID:27649628), (PMID:6337154)
RGD GO_Central
PMID:6337154 PMID:10617578 PMID:12045255 PMID:27649628 PMID:21321306
GO_REF:0000033, RGD:5132599
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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