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ONTOLOGY REPORT - ANNOTATIONS


Term:endochondral ossification
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Accession:GO:0001958 term browser browse the term
Definition:Replacement ossification wherein bone tissue replaces cartilage.
Synonyms:xref: Wikipedia:Endochondral_ossification



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endochondral ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated acts_upstream_of_or_within ISO (PMID:20684022) MGI PMID:20684022 NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9664685) Ensembl
MGI
PMID:9664685 GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270
JBrowse link
G BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18539921) Ensembl
MGI
PMID:18539921 GO_REF:0000107 NCBI chr 4:75,191,256...75,210,988
Ensembl chr 4:75,191,257...75,215,906
JBrowse link
G CBS cystathionine beta-synthase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15622513) Ensembl
MGI
PMID:15622513 GO_REF:0000107 NCBI chr13:206,205,942...206,231,363
Ensembl chr13:206,205,946...206,230,248
JBrowse link
G COL10A1 collagen type X alpha 1 chain ISO RGD PMID:10853827 RGD:704421 NCBI chr 1:81,766,829...81,773,818
Ensembl chr 1:81,765,859...81,773,818
JBrowse link
G COL13A1 collagen type XIII alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:72,786,780...72,953,093
Ensembl chr14:72,787,303...72,953,095
JBrowse link
G COL1A1 collagen type I alpha 1 chain acts_upstream_of_or_within ISO (PMID:8130375) MGI PMID:8130375 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004
JBrowse link
G COL2A1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10100048) Ensembl
MGI
PMID:10100048 GO_REF:0000107 NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718
JBrowse link
G CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21148564) MGI
Ensembl
PMID:21148564 GO_REF:0000107 NCBI chr17:12,145,141...12,498,777
Ensembl chr17:12,428,893...12,498,585
JBrowse link
G DLX5 distal-less homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:76,639,915...76,643,689
Ensembl chr 9:76,639,561...76,643,884
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:24770645) MGI PMID:24770645 NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21185280), (PMID:23958822) Ensembl
MGI
PMID:21185280 PMID:23958822 GO_REF:0000107 NCBI chr 4:20,645,002...20,935,769
Ensembl chr 4:20,645,610...20,935,540
JBrowse link
G FGF18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17014841) Ensembl
MGI
PMID:17014841 GO_REF:0000107 NCBI chr16:52,724,867...52,760,246
Ensembl chr16:52,725,356...52,759,791
JBrowse link
G FOXC1 forkhead box C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:837,088...840,593
Ensembl chr 7:837,171...838,805
JBrowse link
G GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25107907) MGI
Ensembl
PMID:25107907 GO_REF:0000107 NCBI chr15:72,276,502...72,343,524
Ensembl chr15:72,293,614...72,342,435
JBrowse link
G GNAS GNAS complex locus involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15797856) Ensembl
MGI
PMID:15797856 GO_REF:0000107 NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021
JBrowse link
G HSPG2 heparan sulfate proteoglycan 2 acts_upstream_of_or_within ISO (PMID:10579729) MGI PMID:10579729 NCBI chr 6:79,849,691...79,958,283
Ensembl chr 6:79,849,698...79,958,334
JBrowse link
G IFT80 intraflagellar transport 80 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:26098911) Ensembl
MGI
PMID:26098911 GO_REF:0000107 NCBI chr13:99,943,203...100,078,148
Ensembl chr13:99,943,208...100,078,148
JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in
acts_upstream_of_or_within
ISS
ISO
(PMID:17336904) UniProt
MGI
PMID:17336904 GO_REF:0000024 NCBI chr 2:96,122,407...96,296,927
Ensembl chr 2:96,124,168...96,296,810
JBrowse link
G MEF2D myocyte enhancer factor 2D involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17336904) Ensembl
MGI
PMID:17336904 GO_REF:0000107 NCBI chr 4:93,581,563...93,616,980
Ensembl chr 4:93,581,598...93,616,983
JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in ISO
IEA
RGD
Ensembl
PMID:10646117 GO_REF:0000107 RGD:10043159 NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162
JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18022611) Ensembl
MGI
PMID:18022611 GO_REF:0000107 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928
JBrowse link
G MMP16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18022611) Ensembl
MGI
PMID:18022611 GO_REF:0000107 NCBI chr 4:48,556,826...48,867,959
Ensembl chr 4:48,556,967...48,862,985
JBrowse link
G NAB1 NGFI-A binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16136673) Ensembl
MGI
PMID:16136673 GO_REF:0000107 NCBI chr15:95,248,703...95,295,078
Ensembl chr15:95,248,814...95,295,081
JBrowse link
G NAB2 NGFI-A binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16136673) Ensembl
MGI
PMID:16136673 GO_REF:0000107 NCBI chr 5:22,400,275...22,406,424
Ensembl chr 5:22,400,277...22,406,419
JBrowse link
G NFIX nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chr 2:65,954,808...66,056,591
Ensembl chr 2:65,954,811...66,056,567
JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:236,508,994...236,529,172
Ensembl chr 1:236,508,998...236,529,128
JBrowse link
G PEX7 peroxisomal biogenesis factor 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12915479) Ensembl
MGI
PMID:12915479 GO_REF:0000107 NCBI chr 1:27,257,872...27,346,529
Ensembl chr 1:27,257,011...27,346,515
JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO (PMID:20684022) MGI PMID:20684022 NCBI chr12:25,441,564...25,449,267 JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:8895385) MGI PMID:8895385 NCBI chr 5:45,750,968...45,763,421
Ensembl chr 5:45,751,292...45,763,415
JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10072783) Ensembl
MGI
PMID:10072783 GO_REF:0000107 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISO (PMID:20059955) UniProt PMID:20059955 NCBI chr 4:500,884...503,276
Ensembl chr 4:500,526...503,193
JBrowse link
G SIK3 SIK family kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22318228) Ensembl
MGI
PMID:22318228 GO_REF:0000107 NCBI chr 9:44,223,227...44,471,689
Ensembl chr 9:44,223,232...44,513,831
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21788370)
(PMID:17591962)
(PMID:24505141)
Ensembl
MGI
PMID:17591962 PMID:21788370 PMID:24505141 GO_REF:0000107 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357
JBrowse link
G TEK TEK receptor tyrosine kinase ISO RGD PMID:11735002 RGD:1601509 NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,432...196,051,980
JBrowse link
G TMEM119 transmembrane protein 119 involved_in ISO (PMID:22416756) ARUK-UCL PMID:22416756 NCBI chr14:42,190,958...42,197,384 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18932
    multicellular organismal process 8745
      ossification 492
        replacement ossification 38
          endochondral ossification 38
Path 2
Term Annotations click to browse term
  biological_process 18932
    developmental process 6758
      anatomical structure development 6342
        multicellular organism development 5123
          system development 4469
            skeletal system development 576
              bone development 254
                bone morphogenesis 118
                  endochondral bone morphogenesis 73
                    endochondral ossification 38
paths to the root