Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:neutrophil homeostasis
go back to main search page
Accession:GO:0001780 term browser browse the term
Definition:The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.



show annotations for term's descendants           Sort by:
neutrophil homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO (PMID:21957127) RGD PMID:21957127 NCBI chr 1:227,287,713...227,306,739 JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:32484067 RGD:151665124 NCBI chr  X:102,016,070...102,055,448 JBrowse link
G C5 complement C5 acts_upstream_of_or_within ISO (PMID:16769899) RGD PMID:16769899 NCBI chr 3:38,668,174...38,759,468 JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:16769899) RGD PMID:16769899 NCBI chr13:51,512,376...51,613,829 JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (PMID:9215625) RGD PMID:9215625 NCBI chr 2:198,065,400...198,084,774 JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:24056626 PMID:18987110 PMID:21519331 PMID:18434589 RGD:151665812, RGD:2314607, RGD:151665824, RGD:151665814 NCBI chr18:56,834,152...56,860,804 JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:29853563)
GO_REF:0000107
RGD
Ensembl
PMID:29853563 GO_REF:0000107 NCBI chr15:16,538,881...16,574,468 JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 acts_upstream_of_or_within ISO MGI:3849682 (PMID:19349303) RGD PMID:19349303 NCBI chr 2:28,253,325...28,283,082 JBrowse link
G Jam3 junctional adhesion molecule 3 acts_upstream_of_or_within ISO MGI:3055281 (PMID:17455169) RGD PMID:17455169 NCBI chr 8:25,508,461...25,569,306 JBrowse link
G Mecom MDS1 and EVI1 complex locus acts_upstream_of_or_within ISO MGI:2158381 (PMID:17029558) RGD PMID:17029558 NCBI chr 2:114,837,815...115,393,052 JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor IMP RGD PMID:10606160 RGD:10449003 NCBI chr 5:131,973,895...131,987,472 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:23704330)
Ensembl
RGD
PMID:23704330 GO_REF:0000107 NCBI chr 6:94,977,862...95,045,375 JBrowse link
G Pde4b phosphodiesterase 4B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181444 (PMID:15585880)
Ensembl
RGD
PMID:15585880 GO_REF:0000107 NCBI chr 5:122,028,956...122,598,267 JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA
UniProtKB:P35951 (PMID:27430239)
GO_REF:0000107
RGD
Ensembl
PMID:27430239 GO_REF:0000107 NCBI chr12:34,731,934...34,753,617 JBrowse link
G Slc37a4 solute carrier family 37 member 4 acts_upstream_of_or_within ISO MGI:3046091 (PMID:16891306) RGD PMID:16891306 NCBI chr 8:53,619,952...53,626,110 JBrowse link
G Tspan9 tetraspanin 9 acts_upstream_of_or_within ISO MGI:6719497 (PMID:34048705) RGD PMID:34048705 NCBI chr 4:160,813,879...160,995,574 JBrowse link
negative regulation of neutrophil apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:22312020 RGD:7257693 NCBI chr 9:75,729,493...75,735,868 JBrowse link
G Fcgr2b Fc gamma receptor 2B IMP RGD PMID:19106808 RGD:5147925 NCBI chr13:85,725,897...85,740,517 JBrowse link
G Il18 interleukin 18 IMP RGD PMID:20844839 RGD:8655995 NCBI chr 8:59,802,072...59,829,275 JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO MGI:2680720 (PMID:18339802) RGD PMID:18339802 NCBI chr13:94,601,072...94,696,180 JBrowse link
neutrophil apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hcar2 hydroxycarboxylic acid receptor 2 involved_in ISO (PMID:17932499) RGD PMID:17932499 NCBI chr12:32,726,252...32,728,238 JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO MGI:1857184 (PMID:12925700) RGD PMID:12925700 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Il6 interleukin 6 involved_in
acts_upstream_of_or_within
ISO (PMID:7595060)
MGI:1857197 (PMID:12925700)
RGD PMID:7595060 PMID:12925700 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:8986723) RGD PMID:8986723 NCBI chr 1:192,089,496...192,139,947 JBrowse link
neutrophil clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO
IEA
(PMID:21957127)
GO_REF:0000107
RGD
Ensembl
PMID:21957127 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739 JBrowse link
G Axl Axl receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:96965 (PMID:23878224) RGD PMID:23878224 NCBI chr 1:90,392,864...90,424,123 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 acts_upstream_of_or_within ISO MGI:2158345 (PMID:9342361) RGD PMID:9342361 NCBI chr 8:132,611,883...132,619,106 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO
ISS
(PMID:18768881)
GO_REF:0000024
RGD
UniProt
PMID:18768881 GO_REF:0000024 NCBI chr12:11,009,236...11,015,941 JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase acts_upstream_of_or_within ISO MGI:1347244 (PMID:23878224) RGD PMID:23878224 NCBI chr 3:136,391,936...136,498,366 JBrowse link
G Xkr8 XK related 8 involved_in ISO (PMID:29440417) RGD PMID:29440417 NCBI chr 5:144,938,061...144,945,195 JBrowse link
positive regulation of neutrophil apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21957127)
Ensembl
RGD
PMID:21957127 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739 JBrowse link
G Cd44 CD44 molecule IMP RGD PMID:11044212 RGD:2289387 NCBI chr 3:109,610,824...109,699,776 JBrowse link
G Fcar Fc alpha receptor involved_in ISO (PMID:25339672) RGD PMID:25339672 NCBI chr 1:69,626,458...69,660,558 JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 involved_in ISO
ISS
(PMID:17932499)
GO_REF:0000024
RGD
UniProt
PMID:17932499 GO_REF:0000024 NCBI chr12:32,726,252...32,728,238 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in ISO (PMID:25339672) RGD PMID:25339672 NCBI chr 8:108,474,017...108,579,140 JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta involved_in ISO (PMID:25339672) RGD PMID:25339672 NCBI chr 5:165,377,994...165,426,620 JBrowse link
regulation of neutrophil apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:3608695 (PMID:17200146) RGD PMID:17200146 NCBI chr 2:136,532,912...136,668,560 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      leukocyte homeostasis 141
        neutrophil homeostasis 34
          neutrophil apoptotic process + 14
          neutrophil clearance 6
Path 2
Term Annotations click to browse term
  biological_process 20534
    homeostatic process 2014
      multicellular organismal-level homeostasis 975
        homeostasis of number of cells 428
          leukocyte homeostasis 141
            neutrophil homeostasis 34
              neutrophil apoptotic process + 14
              neutrophil clearance 6
paths to the root