ONTOLOGY REPORT - ANNOTATIONS
Term: immunological synapse formation
Accession: GO:0001771
browse the term
Definition: The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
Synonyms: exact_synonym: formation of immunological synapse
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Ccl19
C-C motif chemokine ligand 19
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chrNW_004936524:2,765,271...2,767,259
Ensembl chrNW_004936524:2,765,267...2,767,385
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Ccl21
C-C motif chemokine ligand 21
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chrNW_004936524:2,787,963...2,789,116
Ensembl chrNW_004936524:2,788,341...2,789,016
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Cd2ap
CD2 associated protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14512504)
Ensembl MGI
PMID:14512504
GO_REF:0000107
NCBI chrNW_004936476:12,890,595...12,989,046
Ensembl chrNW_004936476:12,890,468...12,987,843
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Cd6
CD6 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936581:1,932,596...1,943,671
Ensembl chrNW_004936581:1,932,668...1,969,126
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Cd81
CD81 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936794:664,089...670,294
Ensembl chrNW_004936794:664,115...669,800
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Coro1a
coronin 1A
NOT|involved_in
ISO
(PMID:24760828)
UniProt
PMID:24760828
NCBI chrNW_004936501:12,338,542...12,344,236
Ensembl chrNW_004936501:12,338,542...12,344,265
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Dlg1
discs large MAGUK scaffold protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:15699074)
Ensembl MGI
PMID:15699074
GO_REF:0000107
NCBI chrNW_004936833:551,989...843,064
Ensembl chrNW_004936833:551,799...844,121
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Dock2
dedicator of cytokinesis 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12871644)
Ensembl MGI
PMID:12871644
GO_REF:0000107
NCBI chrNW_004936609:4,695,202...5,099,038
Ensembl chrNW_004936609:4,695,628...5,099,038
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Dock8
dedicator of cytokinesis 8
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:22006977)
MGI Ensembl
PMID:22006977
GO_REF:0000107
NCBI chrNW_004936503:4,362,573...4,575,307
Ensembl chrNW_004936503:4,363,926...4,574,932
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Ephb1
EPH receptor B1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chrNW_004936529:8,006,780...8,261,923
Ensembl chrNW_004936529:7,839,768...8,261,942
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Git1
GIT ArfGAP 1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chrNW_004936538:5,684,660...5,694,779
Ensembl chrNW_004936538:5,684,644...5,695,043
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Msn
moesin
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936635:2,390,390...2,461,870
Ensembl chrNW_004936635:2,389,823...2,461,930
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Nck2
NCK adaptor protein 2
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chrNW_004936764:141,159...185,482
Ensembl chrNW_004936764:140,946...185,529
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Prf1
perforin 1
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936521:8,057,874...8,060,695
Ensembl chrNW_004936521:8,057,874...8,060,695
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Havcr2
hepatitis A virus cellular receptor 2
involved_in
ISO
(PMID:24337741)
UniProt
PMID:24337741
NCBI chrNW_004936515:6,001,324...6,015,407
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Lgals3
galectin 3
involved_in
ISO
(PMID:19706535)
BHF-UCL
PMID:19706535
NCBI chrNW_004936697:20,861...38,568
Ensembl chrNW_004936697:27,145...38,586
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Ccr7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
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Ccr7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
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Nedd9
neural precursor cell expressed, developmentally down-regulated 9
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936534:1,816,755...1,863,200
Ensembl chrNW_004936534:1,760,142...1,863,565
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