ONTOLOGY REPORT - ANNOTATIONS
Term: immunological synapse formation
Accession: GO:0001771
browse the term
Definition: The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
Synonyms: exact_synonym: formation of immunological synapse
G
CCL19
C-C motif chemokine ligand 19
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365
G
CCL21
C-C motif chemokine ligand 21
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chr11:51,375,107...51,375,790
G
CD2AP
CD2 associated protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14512504)
Ensembl MGI
PMID:14512504
GO_REF:0000107
NCBI chr12:15,538,215...15,683,619
Ensembl chr12:15,538,356...15,681,011
G
CD6
CD6 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr18:55,296,116...55,336,014
Ensembl chr18:55,296,986...55,335,880
G
CD81
CD81 molecule
involved_in
ISO
(PMID:23858057)
UniProt
PMID:23858057
NCBI chr18:46,466,484...46,474,236
Ensembl chr18:46,466,499...46,473,868
G
CORO1A
coronin 1A
NOT|involved_in
ISO
(PMID:24760828)
UniProt
PMID:24760828
NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818
G
DLG1
discs large MAGUK scaffold protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:15699074)
Ensembl MGI
PMID:15699074
GO_REF:0000107
NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547
G
DOCK2
dedicator of cytokinesis 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12871644)
Ensembl MGI
PMID:12871644
GO_REF:0000107
NCBI chr 4:41,779,950...42,177,957
Ensembl chr 4:41,780,436...42,235,177
G
DOCK8
dedicator of cytokinesis 8
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22006977)
Ensembl MGI
PMID:22006977
GO_REF:0000107
NCBI chr 1:89,152,456...89,379,203
Ensembl chr 1:89,150,856...89,378,013
G
EPHB1
EPH receptor B1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr23:31,485,701...31,918,754
Ensembl chr23:31,485,534...31,917,393
G
GIT1
GIT ArfGAP 1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr 9:43,676,707...43,686,566
Ensembl chr 9:43,677,899...43,693,177
G
MSN
moesin
involved_in
ISO
(PMID:27405666)
UniProt
PMID:27405666
NCBI chr X:50,708,913...50,775,404
Ensembl chr X:50,708,704...50,773,762
G
NCK2
NCK adaptor protein 2
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994
G
PRF1
perforin 1
involved_in
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 4:21,497,865...21,502,429
Ensembl chr 4:21,498,249...21,500,864
G
HAVCR2
hepatitis A virus cellular receptor 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
G
LGALS3
galectin 3
involved_in
ISO
(PMID:19706535)
BHF-UCL
PMID:19706535
NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705
G
CCR7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656
G
CCR7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656
G
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr35:10,852,334...11,033,656
Ensembl chr35:10,854,295...10,964,650
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all