ONTOLOGY REPORT - ANNOTATIONS
Term: immunological synapse formation
Accession: GO:0001771
browse the term
Definition: The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
Synonyms: exact_synonym: formation of immunological synapse
G
CCL19
C-C motif chemokine ligand 19
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108
G
CCL21
C-C motif chemokine ligand 21
involved_in
ISO
(PMID:15845453)
BHF-UCL
PMID:15845453
NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924
G
CD2AP
CD2 associated protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14512504)
Ensembl MGI
PMID:14512504
GO_REF:0000107
NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163
G
CD6
CD6 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr11:56,269,585...56,283,516
Ensembl chr11:59,675,221...59,722,916
G
CD81
CD81 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr11:2,400,503...2,421,132
Ensembl chr11:2,437,991...2,449,308
G
CORO1A
coronin 1A
NOT|involved_in
ISO
(PMID:24760828)
UniProt
PMID:24760828
Ensembl chr16:30,550,383...30,556,196
G
DLG1
discs large MAGUK scaffold protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:15699074)
Ensembl MGI
PMID:15699074
GO_REF:0000107
NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987
G
DOCK2
dedicator of cytokinesis 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12871644)
Ensembl MGI
PMID:12871644
GO_REF:0000107
NCBI chr 5:165,000,368...165,447,148
Ensembl chr 5:171,778,952...172,206,238
G
DOCK8
dedicator of cytokinesis 8
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22006977)
Ensembl MGI
PMID:22006977
GO_REF:0000107
NCBI chr 9:6,791...256,837
Ensembl chr 9:201,156...446,910
G
EPHB1
EPH receptor B1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802
G
GIT1
GIT ArfGAP 1
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr17:27,185,025...27,201,146
Ensembl chr17:27,706,776...27,717,857
G
MSN
moesin
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr X:54,785,309...54,859,364
Ensembl chr X:64,781,550...64,933,292
G
NCK2
NCK adaptor protein 2
acts_upstream_of_or_within
ISO
PMID:17310244
MGI
PMID:17310244
RGD:10047256
NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
G
PRF1
perforin 1
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr10:67,071,141...67,078,057
Ensembl chr10:69,597,574...69,603,070
G
HAVCR2
hepatitis A virus cellular receptor 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:152,486,125...152,514,004
Ensembl chr 5:159,108,915...159,131,007
G
LGALS3
galectin 3
involved_in
ISO
(PMID:19706535)
BHF-UCL
PMID:19706535
NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412
G
CCR7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:16,720,236...16,731,955
Ensembl chr17:16,949,119...16,956,370
G
CCR7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:16,720,236...16,731,955
Ensembl chr17:16,949,119...16,956,370
G
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:11,022,321...11,071,747
Ensembl chr 6:11,297,701...11,420,186
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all