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ONTOLOGY REPORT - ANNOTATIONS


Term:establishment of T cell polarity
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Accession:GO:0001768 term browser browse the term
Definition:The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
Synonyms:exact_synonym: T cell polarization;   T lymphocyte polarization;   establishment of T lymphocyte polarity



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establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:12729902) RGD PMID:12729902 NCBI chr 5:56,963,364...56,965,308 JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:12729902) RGD PMID:12729902 NCBI chr 5:56,980,557...56,981,661 JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:18329370) RGD PMID:18329370 NCBI chr 8:41,340,117...41,377,381 JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 acts_upstream_of_or_within ISO MGI:3764691 (PMID:23991089) RGD PMID:23991089 NCBI chr 4:117,041,808...117,058,628 JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO MGI:2152031 (PMID:12871644) RGD PMID:12871644 NCBI chr10:19,331,412...19,748,987 JBrowse link
G Myh9 myosin, heavy chain 9 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15064761)
Ensembl
RGD
PMID:15064761 GO_REF:0000107 NCBI chr 7:111,224,291...111,304,963 JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:18329370) RGD PMID:18329370 NCBI chr 7:107,759,343...107,782,364 JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:3510784 (PMID:21856933) RGD PMID:21856933 NCBI chr20:43,011,405...43,054,654 JBrowse link
negative regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO
ISS
(PMID:23241886)
GO_REF:0000024
RGD
UniProt
PMID:23241886 GO_REF:0000024 NCBI chr17:40,323,748...40,547,482 JBrowse link
positive regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:22810897) RGD PMID:22810897 NCBI chr 3:35,377,587...35,480,843 JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase involved_in ISO (PMID:22810897) RGD PMID:22810897 NCBI chr13:71,223,902...71,319,770 JBrowse link
G Dock8 dedicator of cytokinesis 8 involved_in ISO
IBA
(PMID:28028151)
GO_REF:0000033
RGD
GO_Central
PMID:28028151 GO_REF:0000033 NCBI chr 1:232,075,468...232,268,830 JBrowse link
G Flot2 flotillin 2 involved_in ISO
IEA
(PMID:21696602)
GO_REF:0000107
RGD
Ensembl
PMID:21696602 GO_REF:0000107 NCBI chr10:63,424,084...63,445,811 JBrowse link
regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO
IEA
(PMID:23575248)
GO_REF:0000107
RGD
Ensembl
PMID:23575248 GO_REF:0000107 NCBI chr 3:38,982,605...39,035,849 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      establishment or maintenance of cell polarity 235
        establishment of cell polarity 168
          establishment of lymphocyte polarity 14
            establishment of T cell polarity 14
              negative regulation of establishment of T cell polarity 1
              positive regulation of establishment of T cell polarity 4
              regulation of establishment of T cell polarity + 6
Path 2
Term Annotations click to browse term
  biological_process 20534
    multicellular organismal process 8969
      cell activation 1226
        leukocyte activation 1070
          lymphocyte activation 867
            T cell activation 616
              establishment of T cell polarity 14
                negative regulation of establishment of T cell polarity 1
                positive regulation of establishment of T cell polarity 4
                regulation of establishment of T cell polarity + 6
paths to the root