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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA regulatory element binding translation repressor activity
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Accession:GO:0000900 term browser browse the term
Definition:Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
Synonyms:broad_synonym: translation repressor activity, nucleic acid binding
 xref: Reactome:R-HSA-5690886 "ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs"

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mRNA regulatory element binding translation repressor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chrNW_004936524:1,081,672...1,134,971
Ensembl chrNW_004936524:1,081,696...1,134,971 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936483:17,216,288...17,296,430
Ensembl chrNW_004936483:17,216,213...17,294,534 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936477:12,727,325...12,798,733 JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936601:2,470,021...2,616,451
Ensembl chrNW_004936601:2,470,036...2,610,942 		JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936609:1,793,027...1,858,586
Ensembl chrNW_004936609:1,793,027...1,858,597 		JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:8490020) CAFA PMID:8490020 NCBI chrNW_004936469:67,962...83,116 JBrowse link
G Ireb2 iron responsive element binding protein 2 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636 		JBrowse link
G Paip2 poly(A) binding protein interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936531:8,431,950...8,453,980
Ensembl chrNW_004936531:8,431,798...8,456,498 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936491:15,197,028...15,233,652
Ensembl chrNW_004936491:15,202,794...15,233,652 		JBrowse link
G Pura purine rich element binding protein A enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936531:9,129,024...9,134,916
Ensembl chrNW_004936531:9,129,715...9,130,515 		JBrowse link
G Purb purine rich element binding protein B enables ISO PMID:12933792 HGNC-UCL PMID:12933792 RGD:1581942 NCBI chrNW_004936478:19,738,252...19,747,345 JBrowse link
G Rara retinoic acid receptor alpha ISO RGD PMID:19073915 RGD:2314253 NCBI chrNW_004936490:15,376,217...15,420,638
Ensembl chrNW_004936490:15,376,205...15,421,611 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936741:1,849,239...1,877,724
Ensembl chrNW_004936741:1,849,609...1,877,727 		JBrowse link
G Tyms thymidylate synthetase enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840 		JBrowse link
G Znf540 zinc finger protein 540 enables ISO (PMID:16815308) UniProt PMID:16815308 NCBI chrNW_004936801:481,223...528,848 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18185
    translation regulator activity 116
      translation repressor activity 25
        mRNA regulatory element binding translation repressor activity 15
Path 2
Term Annotations click to browse term
  molecular_function 18185
    binding 16304
      nucleic acid binding 4039
        translation regulator activity, nucleic acid binding 94
          mRNA regulatory element binding translation repressor activity 15
paths to the root